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Medicinal composition for treating sjogren syndrome and preparation method thereof and application

A technology of Sjögren's syndrome and composition, which is applied in the field of preparation containing it, can solve problems such as insufficient effects, and achieve the effects of not being easy to repeat, having obvious effects, and relieving symptoms

Active Publication Date: 2020-10-13
BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, these prescriptions have their own emphasis on the mechanism of treating Sjögren's syndrome, and the effect is not comprehensive enough. More effective Chinese medicine compositions for treating Sjögren's syndrome are still needed.

Method used

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preparation example Construction

[0050] The traditional Chinese medicine composition of the present invention can be prepared by various preparation methods. Preferably, the preparation method is a water extraction method, for example, comprising using water as a solvent to extract the raw material drug. The extraction method is selected from decoction, heating reflux extraction or ultrasonic extraction. According to one embodiment of the present invention, the preparation method of the pharmaceutical composition comprises the following steps: adding water to decoct the raw material drug, the amount of water added each time is 2 to 6 times the total weight of each raw material drug, and the number of decoctions is 1 to 6 times. 3 times, each decocting time is 10 to 30 minutes, remove the dregs of the medicine, and obtain the extract. The extract can also be further concentrated and dried.

[0051]

[0052] The present invention also provides a pharmaceutical preparation for treating Sjögren's syndrome, wh...

Embodiment 1

[0055]20 parts by weight of raw land, 24 parts by weight of Scrophulariaceae, 20 parts by weight of Ophiopogon japonicus, 30 parts by weight of white peony, 10 parts by weight of licorice, 20 parts by weight of mulberry leaves, 15 parts by weight of chrysanthemum, 15 parts by weight of Citrus aurantii, 20 parts by weight of Ligustrum lucidum 30 parts by weight of kudzu root and 20 parts by weight of Qingfengteng add water and decoct, the amount of water added each time is 3 times of the total dose, the number of times of decoction is 2 times, the first decoction time is 20 minutes, the second decoction The cooking time is 10 minutes, and the dregs of the medicine are removed to obtain the extract. The extract is concentrated and dried to obtain the traditional Chinese medicine composition.

Embodiment 2

[0057] 20 parts by weight of raw land, 24 parts by weight of Scrophulariaceae, 20 parts by weight of Ophiopogon japonicus, 30 parts by weight of white peony, 10 parts by weight of licorice, 20 parts by weight of mulberry leaves, 15 parts by weight of chrysanthemum, 15 parts by weight of Citrus aurantii, 20 parts by weight of Ligustrum lucidum 30 parts by weight of kudzu root, 20 parts by weight of Radix Sinensis, 15 parts by weight of Radix Astragali and 15 parts by weight of Angelica sinensis, add water and decoct, the amount of water added each time is 3 times of the total amount of medicine, the number of times of decoction is 2 times, the first decoction The cooking time is 20 minutes, and the decocting time for the second time is 10 minutes, and the medicinal residues are removed to obtain the extract. The extract is concentrated and dried to obtain the traditional Chinese medicine composition.

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Abstract

The invention discloses a medicinal composition for treating sjogren syndrome and a preparation method thereof and an application. The medicinal composition is prepared from components including the following raw materials; 15-25 parts by weight of radix rehmanniae, 20-30 parts by weight of radix scrophulariae, 15-25 parts by weight of radix ophiopogonis, 25-35 parts by weight of radix paeoniae alba, 5-15 parts by weight of radix glycyrrhizae, 15-25 parts by weight of mulberry leaves, 10-20 parts by weight of flos chrysanthemi, 10-20 parts by weight of fructus aurantii, 15-25 parts by weight of fructus ligustri lucidi, 25-35 parts by weight of radix puerariae, and 15-25 parts by weight of caulis sinomenii. The medicinal composition of the present invention has significant effect on treating sjogren syndrome.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating Sjögren's syndrome, and also relates to a preparation method and application thereof. Background technique [0002] Sjögren's syndrome, also known as autoimmune exocrine adenopathy, Sjögren's syndrome, scleroarthritis syndrome, etc., is a chronic autoimmune disease that invades exocrine glands, mainly salivary glands and lacrimal glands. immune disease. The main clinical symptoms of Sjögren's syndrome include dry cornea, conjunctivitis, dry mouth, enlarged parotid gland, dry skin, joint pain, swelling, and dry changes in other parts such as ears, nose, respiratory system, digestive tract, and urinary system. . Sjögren's syndrome is often accompanied by other rheumatic diseases or autoimmune diseases, and the incidence of women is more than that of men, with a male to female ratio of about 1:9. [0003] At present, there are many traditional Chinese medicine prescriptions for the clin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P37/02A61P1/02A61P27/02A61P29/00A61P19/02
CPCA61K36/00A61K36/232A61K36/28A61K36/287A61K36/481A61K36/484A61K36/488A61K36/537A61K36/538A61K36/59A61K36/605A61K36/638A61K36/65A61K36/71A61K36/716A61K36/75A61K36/752A61K36/804A61K36/808A61K36/8968A61P1/02A61P19/02A61P27/02A61P29/00A61P37/02A61K2300/00
Inventor 吴晓丹杨勇张加余张林王坦
Owner BEIJING UNIV OF CHINESE MEDICINE
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