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Traditional Chinese medicine composition for treating cancer pain caused by bone metastasis and preparation method and application thereof

A composition and bone transfer technology, applied in drug combinations, antineoplastic drugs, pharmaceutical formulations, etc., can solve problems affecting the quality of life of advanced cancer patients, affecting treatment compliance, and patient addiction

Inactive Publication Date: 2020-08-28
CHONGQING TRADITIONAL CHINESE MEDICINE HOSPITAL
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, as the condition of advanced cancer patients progresses, the therapeutic dose of opioids gradually increases. Long-term use will cause adverse reactions such as drowsiness, constipation, drug tolerance and addiction, which greatly affects the life expectancy of advanced cancer patients. quality of life, and even affect their compliance with treatment, thereby affecting their survival time

Method used

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  • Traditional Chinese medicine composition for treating cancer pain caused by bone metastasis and preparation method and application thereof
  • Traditional Chinese medicine composition for treating cancer pain caused by bone metastasis and preparation method and application thereof
  • Traditional Chinese medicine composition for treating cancer pain caused by bone metastasis and preparation method and application thereof

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preparation example Construction

[0043] The invention provides a preparation method of the above-mentioned Chinese medicine composition, comprising:

[0044] mixing the raw materials with water, decocting and filtering for the first time to obtain the first liquid medicine and the first medicine dregs; mixing the first medicine dregs and water for the second decoction and filtering to obtain the second medicine liquid and the second medicinal residue, after mixing the first medicinal liquid and the second medicinal liquid, the Chinese medicine composition is obtained; during the first decoction, the mass ratio of the required water to the total raw material is (10~12): 1; During the second decoction, the mass ratio of water to total raw materials is (7-9):1.

[0045] In the present invention, the time for the first decoction and the second decoction is preferably 45-60 minutes respectively.

[0046] In the present invention, the first medicinal liquid and the second medicinal liquid are preferably mixed to o...

Embodiment 1

[0054] According to the following mass parts: 30 parts of Astragalus, 30 parts of Ligustrum lucidum, 15 parts of Sangji, 15 parts of Muxiang, 15 parts of Shandougen, 15 parts of saponins, 15 parts of Shanzi mushroom, 10 parts of trigonum, 10 parts of curcuma 10 parts of Prunella vulgaris, 15 parts of Moutan Cortex, 15 parts of Mildew Spatholobus and 10 parts of Zhi Licorice.

[0055] Specifically: Take 30g of Astragalus, 30g of Ligustrum lucidum, 15g of mulberry, 15g of woody fragrance, 15g of mountain bean root, 15g of saponin thorn, 15g of Shanzi mushroom, 10g of trigonum, 10g of curcuma, 10g of Prunella vulgaris, 15g of Moutan bark, Mildew Spatholobus 15g and Radix Glycyrrhizae 10g. After soaking the above medicines in clear water for half an hour, decoct them twice. Add 2050g of water for the first time, decoct for 45min, add 1640g of water for the second time, decoct for 45min. The two decoctions were mixed and concentrated under reduced pressure, and the mixture was co...

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Abstract

The invention provides a traditional Chinese medicine composition for treating cancer pain caused by bone metastasis and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine compositions. The traditional Chinese medicine composition is prepared from, by mass, 10-50 parts of milkvetch roots, 10-50 parts of glossy privet fruits, 5-35 partsof herba taxilli, 5-35 parts of radix aucklandiae, 5-35 parts of radix sophorae subprostratae, 5-35 parts of spina gleditsiae, 5-35 parts of pseudobulbus cremastrae seu pleiones, 5-30 parts of rhizomasparganii, 5-30 parts of rhizoma curcumae, 5-30 parts of spica prunellae, 5-35 parts of cortex moutan, 5-35 parts of caulis spatholobi and 5-30 parts of radix glycyrrhizae preparata. The traditionalChinese medicine composition can achieve the analgesic effect and is free of side effects on the human body.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for treating cancer pain caused by bone metastases, a preparation method and application thereof. Background technique [0002] In recent years, the incidence of cancer has been increasing, and one of the main symptoms of cancer is cancer pain, and the incidence of cancer pain in patients with malignant tumors can reach 31% to 90%. Cancer pain is also an important issue affecting the quality of life of patients with advanced cancer. Bone tissue is the site where most malignant tumors metastasize except the lung and liver, and nearly 80% of malignant tumors can metastasize to bone. Pain is the most prominent symptom of bone metastases, which will bring great suffering to patients. [0003] For the pain caused by bone metastases, there are analgesics, radiation therapy, bisphosphonates, surgery and other treatment...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P29/00A61P35/04
CPCA61K36/185A61K36/285A61K36/481A61K36/483A61K36/484A61K36/486A61K36/489A61K36/536A61K36/638A61K36/65A61K36/71A61K36/898A61K36/902A61K36/9066A61K2236/331A61K2236/39A61K2236/51A61P29/00A61P35/04A61K2300/00
Inventor 宋娜黎颖冉强王静郑丹丹赖宗浪郭小红
Owner CHONGQING TRADITIONAL CHINESE MEDICINE HOSPITAL
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