Anti-aging nano composition as well as preparation method and application thereof

A nano-composition and composition technology, applied in the direction of pharmaceutical formulations, cosmetic preparations, dressing preparations, etc., can solve problems such as limited anti-aging effects, achieve effective anti-aging products, reduce costs, and save usage.

Active Publication Date: 2020-07-31
泉后(广州)生物科技研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the many causes of skin aging, the anti-aging effect of single-ingredient / mechanism products is limited, and often cannot meet the needs of all consumers

Method used

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  • Anti-aging nano composition as well as preparation method and application thereof
  • Anti-aging nano composition as well as preparation method and application thereof
  • Anti-aging nano composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] An embodiment of the anti-aging nano composition of the present invention includes the following components in mass percentage: 10% fat-soluble anti-aging active ingredient, 15% water-soluble anti-aging active ingredient, 4% emulsifier, 18% emulsifying aid The balance of solvent and deionized water;

[0031] The fat-soluble anti-aging active ingredients include the following components in parts by mass: 30 parts of antioxidants, 35 parts of moisturizing and repairing barrier components and 35 parts of metalloproteinase activity inhibitors; the antioxidants are ergothioneine and resveratrol Alcohol, the mass ratio of which is 1:2; the moisturizing and repairing barrier component is a mixture whose mass ratio is cholesterol: ceramide: fatty acid=3:1:1; the metalloproteinase activity inhibitor is retinol;

[0032] The water-soluble anti-aging active ingredients include the following components in parts by mass: 15 parts of cuticle exfoliating agent, 20 parts of anti-inflam...

Embodiment 2

[0042] An embodiment of the anti-aging nano composition of the present invention is the same as Example 1 except that the following components, contents and ratios are different; it includes the following components in mass percentage: 15% fat-soluble anti-aging active ingredients, 15% water-soluble anti-aging active ingredients, 8% emulsifier, 30% co-emulsifier and the balance of deionized water;

[0043] The fat-soluble anti-aging active ingredients include the following components in parts by mass: 40 parts of antioxidants, 20 parts of moisturizing and repairing barrier components and 40 parts of metalloproteinase activity inhibitors; the antioxidants include coenzyme Q10 and hydroxydecyl ubiquinol Quinone, the mass ratio of which is 1:3; the moisturizing and repairing barrier component is a mass ratio of cholesterol:ceramide:fatty acid=3:1:1 mixture; the metalloproteinase activity inhibitor is hydroxy pinacolone retinoid acid ester;

[0044] The water-soluble anti-aging a...

Embodiment 3

[0048] An embodiment of the anti-aging nano composition of the present invention is the same as Example 1 except for the following components, contents and ratios; it includes the following components in mass percentage: 0.1% fat-soluble anti-aging active ingredients, 12% water-soluble anti-aging active ingredients, 1% emulsifier, 5% co-emulsifier and the balance of deionized water;

[0049] The fat-soluble anti-aging active ingredients include the following components in parts by mass: 35 parts of antioxidants, 35 parts of moisturizing and repairing barrier components and 35 parts of metalloproteinase activity inhibitors; the antioxidants include astaxanthin; the moisturizing The repair barrier component is a mixture of cholesterol: ceramide: fatty acid=3:1:1 in mass ratio; the metalloproteinase activity inhibitor includes retinyl acetate and retinyl palmitate, and its mass ratio is 1 :2;

[0050] The water-soluble anti-aging active ingredients include the following componen...

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Abstract

The invention discloses an anti-aging nano composition as well as a preparation method and application thereof. The nano composition comprises the following components in percentage by mass: 0.1 to 15percent of a fat-soluble anti-aging active ingredient, 0.1 to 20 percent of a water-soluble anti-aging active ingredient, 1 to 15 percent of an emulsifier, 3 to 30 percent of a co-emulsifier and thebalance of deionized water. According to the anti-aging nano composition, in combination with the skin aging physiological structure phenotype and the skin physiological structure change caused by external environment factors, aging resistance is carried out from multiple paths, and the anti-aging nano composition has more comprehensive and effective internal and external effects and adapts to aging caused by different mechanisms; through the use of a nanostructure and the reasonable proportion of the components of the nano composition, while the nano composition has good targeting and transdermal absorption effects, the solubility and stability of the components are improved, the usage amount of the functional components is reduced, the cost is reduced, and a more comprehensive and effective anti-aging product is provided for consumers.

Description

technical field [0001] The invention belongs to the field of cosmetics, and relates to an anti-aging composition, in particular to an anti-aging nano composition and its preparation method and application. Background technique [0002] Skin aging refers to an irreversible process in which specific morphological, biochemical, and biophysical changes in the skin parallel the aging of the entire organism. Skin aging has obvious individual differences. In the physiological structure of skin aging, 1) the DEJ (epidermal-dermal junction) tends to be flat, 2) the thickness of the epidermis and dermis gradually becomes thinner, 3) the superficial dermis, free water, fibrin and The proportion of proteoglycans is unbalanced, the growth factors secreted by cells are reduced, the fibroblasts are reduced, the protein synthesis and secretion function of aging cells is reduced, the extracellular matrix component fibronectin is reduced, and the skin elasticity is changed; 4) The subcutaneou...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/9771A61K8/92A61K8/73A61K8/68A61K8/67A61K8/64A61K8/34A61K8/49A61K8/63A61Q19/00A61Q19/08
CPCA61K8/345A61K8/347A61K8/4946A61K8/4953A61K8/63A61K8/64A61K8/671A61K8/68A61K8/73A61K8/922A61K2800/782A61Q19/00A61Q19/08A61K8/9771A61K8/9794
Inventor 刘露张娇韩志东
Owner 泉后(广州)生物科技研究院有限公司
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