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High performance liquid chromatography column

A high-performance liquid chromatography and column tube technology, applied in the field of high-performance liquid chromatography columns, can solve the problems of decreased resolution, easy collapse of packing ends, deviation of detection data, etc., to prevent the decrease of resolution, fill dead volume, Guaranteed effect of accuracy

Pending Publication Date: 2020-06-05
ANHUI PIOM PHARMA
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the above-mentioned shortcomings existing in the prior art, the present invention provides a high-performance liquid chromatography column, which can effectively overcome the problems existing in the prior art that it is easy to roll on the desktop, resulting in deviation of the detection data, and the end of the high-efficiency adsorption packing is easy to collapse. Defects that lead to reduced resolution

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Embodiment Construction

[0027] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Apparently, the described embodiments are some, but not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

[0028] A high performance liquid chromatography column, such as figure 1 and figure 2 As shown, the first column tube 1 and the second column tube 2 are included, the ends of the first column tube 1 and the second column tube 2 are threadedly connected with the connecting ring 3, and the third filter piece 5 is fixed inside the connecting ring 3. The end of ...

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Abstract

The invention relates to a liquid chromatographic column, in particular to a high-performance liquid chromatographic column. The column comprises a first column pipe and a second column pipe, the endparts of the first column pipe and the second column pipe are in threaded connection with a connecting ring; a third filter disc is fixed in the connecting ring; the end part of the second column pipeis in threaded connection with a second column head; a liquid outlet is formed in the second column head; a second filter disc is fixed in the second column pipe; an anti-collapse mechanism is arranged at the end part of the first column pipe; the anti-collapse mechanism comprises a first column head in threaded connection with the end of the first column pipe, a containing cavity is formed in the first column head, the inner top of the containing cavity is connected with a baffle ring through a spring, a liquid inlet is formed in the first column head, a connecting pipe communicated with theliquid inlet and penetrating through the baffle ring is fixed to the inner top of the containing cavity, and a first filter disc is fixed to the end of the connecting pipe; according to the technicalscheme, the defects that in the prior art, detection data deviates due to the fact that rolling is prone to occurring when the the column is placed on a table top, and the separation degree is reduced due to the fact that the end of efficient adsorption packing collapses easily can be effectively overcome.

Description

technical field [0001] The invention relates to a liquid chromatography column, in particular to a high-performance liquid chromatography column. Background technique [0002] Liquid chromatography separation technology is mainly used for the separation of various components. To achieve high-efficiency separation, high-efficiency adsorption packing must be used, and high-pressure methods must be used to maximize the separation efficiency of high-efficiency adsorption packing. [0003] The liquid chromatograph is mainly composed of a high-pressure liquid pump, a detector and a liquid chromatographic column. Among them, the liquid chromatographic column is the core component of the liquid chromatograph. The liquid is used as the mobile phase, and a high-pressure infusion system is used to pump a single solvent with different polarities or a mixed solvent of different proportions, buffer and other mobile phases into the device. Columns with stationary phases. After the compon...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/60
CPCG01N30/6047G01N30/6052G01N30/60
Inventor 陈正晧苏金月江娟石海贞
Owner ANHUI PIOM PHARMA
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