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Stent and medical device comprising same

A technology of medical equipment and elastic yarn, which is applied in the field of biodegradable stents, can solve the problems of large resistance and difficulty in expanding the end of the stent, and achieve the effect of expansion, high recovery from deformation, and reliable expansion

Pending Publication Date: 2020-06-02
EA PHARMA CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, even with the end treatment, there are problems such as high resistance when released from the delivery system, and difficulty in expanding the end of the released stent.

Method used

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  • Stent and medical device comprising same
  • Stent and medical device comprising same
  • Stent and medical device comprising same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0088] As a biodegradable polymer, polyglycolic acid with an intrinsic viscosity of 1.51dL / g (0.1g / dL HFIP, 25°C) is used, melt-spun at a temperature of 190-245°C, and stretched to a draw ratio 4 to 5 times, heat setting was carried out at a temperature of 100 to 120°C. The obtained monofilament had a diameter of 0.265 mm. Using this monofilament, use Figure 6~7 The braiding manufacturing device shown (it is 32 strands of braiding manufacturing device), made Figure 4 bracket shown. The yarns at both ends of the stent were welded by ultrasonic welding, solidified, and bonded so that the bonding points were arranged in two rows in the longitudinal direction.

[0089] The stent has an outer diameter of 20 mm in an expanded state, and three bundles of elastic polyurethane yarns: "Pellethane" (diameter: 70 μm) manufactured by Lubrizol in the United States (diameter: 70 μm) are inserted at equal intervals on the circumference. 4 places. In addition, the braiding angle θ of ea...

Embodiment 2

[0094] Using 32 monofilaments (0.23 mm in diameter) made of polyglycolic acid, a braided stent (22 mm in diameter and 80 mm in length) was produced with a braiding manufacturing device. On the braided bracket, polyurethane elastic yarn (USA Lubrizol company, trade name "Pellethane" (200 μm in diameter)) such as Figure 9As shown, it is arranged on the outside of the bracket and fixed at both ends of the bracket. Wherein, the two ends of the bracket are arranged in two rows in the length direction. Four polyurethane elastic yarns were arranged at equal intervals on the circumference of the holder. When the braided yarn holder is mounted on Figure 8 After the delivery system with an inner diameter of 3mm as shown, the stent self-expands when pushed out of the delivery system, the central part of the stent expands to the original diameter of 22mm, and the two ends expand to 22-27mm larger than the original diameter. exist Figure 13 In A, a side photo of the stent before the...

Embodiment 3

[0096] In addition to making polyurethane elastic yarns such as Figure 10 A braid holder was fabricated in the same manner as in Example 2, except that the monofilament constituting the braid was intersected at the center of the holder as shown. After the braided yarn stent is mounted on a delivery system with an inner diameter of 3 mm, when pushed out from the delivery system, the stent self-expands, the central part of the stent expands to the original diameter of 22 mm, and the two ends expand to 22 mm larger than the original diameter. -27mm. exist Figure 14 In A, a side photo of the stent before the delivery system is shown is shown, in Figure 14 In B, a profile photo just after release from the delivery system is shown, at Figure 14 In C, a profile photograph 3 minutes after release from the delivery system is shown. It was confirmed that the stent of this example can self-expand uniformly in a short time.

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Abstract

Provided is a stent 51C made of a cylindrical braid formed from a plurality of filament yarns containing a biodegradable polymer, wherein connecting points 53a-53d are formed at the ends of the filament yarns constituting the braid so as to be aligned in two or more rows in the longitudinal direction of the braid. Elastic yarns 54a-54d are disposed outside at least a part of the stent 51C and at least a longitudinal part, of the elastic yarns, that includes the vicinity of the ends thereof. One end of each of the elastic yarns is fixed in the vicinity of a stent end, while the other end is fixed at any position in the stent. When the diameter of the stent is contracted, tension may be applied to the elastic yarns. Accordingly, provided are: a stent that is easy to mount to a delivery system and enables an easy expansion operation; and a medical device including this stent.

Description

technical field [0001] The present invention relates to a biodegradable stent for inserting into the ducts of organisms such as digestive tract, bile duct, pancreatic duct, blood vessel, urinary duct, trachea, and medical equipment including the stent. Background technique [0002] The lumen in the body is narrowed due to various reasons, and a stent is often placed as a treatment for the narrowing of the lumen in the body. Usually, the stent is mounted on a delivery system in a tightened state, is delivered to a stenotic site, and is expanded and left there. When expanding the stent, if the stent itself has no self-expanding force or insufficient self-expanding force, it is necessary to insert a balloon inside the stent to expand it. Expansion by the balloon requires skill of the operator so as not to damage the lumen, and it is difficult to apply to a long stenosis or a stenosis of a curved part. On the other hand, a self-expandable stent can be expanded only by releasin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/90
CPCA61F2/90A61F2210/0004A61F2240/001A61F2002/825D10B2401/12D04C1/02D10B2509/06D04C3/48D10B2401/061D04C3/34A61F2/844A61L31/148A61L31/04A61F2/95A61F2002/9511A61F2002/045B29C53/562B29K2995/006B29L2031/7534D10B2331/04D10B2331/10
Inventor 上杉昭二早乙女俊树衣笠纯澄川通人饭岛典子
Owner EA PHARMA CO LTD
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