Method for extracting chemical components of betel nut seeds

Abstract

The invention discloses a method for extracting chemical components of betel nut seeds. According to the invention, ten compounds are separated from the ethyl acetate part of a betel nut seed methanolextract by re-crystallization, silica gel column chromatography, Sephadex LH-20 gel column chromatography and other modern separation methods, and the chemical structures of the compounds are identified by utilizing a modern spectrum technology, wherein the compounds are Helicia cerebroside A (1), (R)-N-((2S,3S,4R,z)-3,4-dihydroxy-1-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)octadec-8-en-2-yl)-2-hydroxydocosanamide (2), (2S,3R)-catechin (3), isorhamnetin (4), beta-sitosterol (5), beta-daucosterol (6), stigmast-4-ene-3-one (7), vanillic acid (8), cyclic-(leucine-tyrosine) (9) and p-hydroxybenzoic acid (10). The structural types of the separated compounds comprise phenols, flavones, steroids, cerebroside esters and cyclic dipeptides, wherein the cerebroside ester compounds are reported in the plant for the first time.

Description

technical field [0001] The invention belongs to the technical field of extracting chemical components of betel nut seeds, in particular to a method for extracting chemical components of betel nut seeds. Background technique [0002] As a traditional Chinese medicine, betel nut is widely distributed in tropical and subtropical regions in southern my country and other countries in South Asia and Southeast Asia. Betel nut is not only a good fruit that is widely eaten at present, but also its peel and seeds can be used as medicine. It is one of the famous and precious "four southern medicines" in my country. Modern studies have shown that betel nut contains a variety of chemical components such as alkaloids, tannins, flavonoids, and terpenoids, which have activities such as promoting digestion, lowering blood pressure, antidepressant, anti-oxidation, anti-inflammatory, anti-parasitic and antibacterial. The chemical composition of seeds has not been fully developed. Therefore, ...

AI Technical Summary

Problems solved by technology

Modern studies have shown that betel nut contains a variety of chemical components such as alkaloids, tannins, flavonoids, and terpenoids, which have activities such as promoting digestion, lowering blood pressure, antidepressant, anti-oxidation, anti-inflammatory, anti-parasitic and antibacterial. Seed chemistry is not fully developed

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