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Pharmaceutical composition for preventing and treating arthritis, and preparation method thereof

A composition and technology for arthritis, applied in the field of pharmaceutical compositions for preventing and treating arthritis and its preparation, can solve the problems of gastrointestinal mucosa irritation, limited use, and large side effects, achieve analgesic effect, and reduce synovial inflammation , Promote softening and absorption effect

Inactive Publication Date: 2020-02-21
SHAANXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the chemical drugs commonly used in the treatment of arthritis are mainly non-steroidal anti-inflammatory drugs, including ibuprofen, aspirin, diclofenac, etc. limited its use in clinical

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A pharmaceutical composition for preventing and treating arthritis, prepared through the following steps:

[0021] S1. Weigh by weight: 20 parts of Tieniuqi, 20 parts of Sangjisheng, 15 parts of Dangguiwei, 20 parts of Kuanjin Teng, 20 parts of Myrrh, 20 parts of Dangguiwei, 15 parts of Notopterygium, 5 parts of Turmeric, Zhifu 5 parts of slices, 5 parts of gardenia, 10 parts of cinnamon, 15 parts of lovage, 10 parts of castor bean, 10 parts of asarum, 5 parts of raw nux, 20 parts of thistle, 20 parts of pine knot;

[0022] S2. Tie Niu Qi, Sang Ji Sheng, Dang Gui Wei, Kuan Jin Teng, Myrrh, Dang Gui Wei, Notopterygium, Turmeric, Zhi Fu Pian, Gardenia, Cinnamon, Du Huo, Castor Bean, Asarum, Raw Horse Money The seeds, thistles, and pine knots are crushed to the nanometer level, dried, and sterilized to obtain traditional Chinese medicine powder;

[0023] S3. Mix the obtained Chinese medicine powder with honey, spread it on a cotton pad, wrap it with a bandage, and change ...

Embodiment 2

[0025] A pharmaceutical composition for preventing and treating arthritis, prepared through the following steps:

[0026] S1. Weigh by weight: 10 parts of Tieniuqi, 10 parts of Sangjisheng, 5 parts of Dangguiwei, 10 parts of Kuanjin Teng, 10 parts of Myrrh, 10 parts of Dangguiwei, 5 parts of Notopterygium, 3 parts of Turmeric, Zhifu 3 parts of slices, 3 parts of gardenia, 5 parts of cinnamon, 5 parts of lovage, 5 parts of castor bean, 5 parts of asarum, 3 parts of raw nux, 10 parts of thistle, 10 parts of pine knot;

[0027] S2. Tie Niu Qi, Sang Ji Sheng, Dang Gui Wei, Kuan Jin Teng, Myrrh, Dang Gui Wei, Notopterygium, Turmeric, Zhi Fu Pian, Gardenia, Cinnamon, Du Huo, Castor Bean, Asarum, Raw Horse Money Seedlings, thistles, and pine knots are crushed to the nanometer level to obtain traditional Chinese medicine powder;

[0028] S3, soak the obtained traditional Chinese medicine powder with 6 times the amount of 80% ethanol solution for 40min, 400w microwave extraction twice...

Embodiment 3

[0030] A pharmaceutical composition for preventing and treating arthritis, prepared through the following steps:

[0031] S1. Weigh by weight: 15 parts of Tieniuqi, 15 parts of Sangjisheng, 10 parts of Dangguiwei, 15 parts of Kuanjin Teng, 15 parts of Myrrh, 15 parts of Dangguiwei, 10 parts of Notopterygium, 4 parts of Turmeric, Zhifu 4 parts of slices, 4 parts of gardenia, 7.5 parts of cinnamon, 10 parts of lovage, 7.5 parts of castor bean, 7.5 parts of asarum, 4 parts of raw nux, 15 parts of thistle, 15 parts of pine knot;

[0032] S2. Tie Niu Qi, Sang Ji Sheng, Dang Gui Wei, Kuan Jin Teng, Myrrh, Dang Gui Wei, Notopterygium, Turmeric, Zhi Fu Pian, Gardenia, Cinnamon, Du Huo, Castor Bean, Asarum, Raw Horse Money Seedlings, thistles, and pine knots are crushed to the nanometer level to obtain traditional Chinese medicine powder;

[0033] S3, soak the obtained traditional Chinese medicine powder with 6 times the amount of 80% ethanol solution for 40min, 400w microwave extract...

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Abstract

The invention discloses a pharmaceutical composition for preventing and treating arthritis. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 10-20 partsof aconitum racemulosum, 10-20 parts of Chinese taxillus herb, 5-15 parts of Chinese angelica tail, 10-20 parts of tinospora sinensis, 10-20 parts of myrrh, 10-20 parts of Chinese angelica tail, 5-15parts of incised notopterygium rhizome and root, 3-5 parts of turmeric, 3-5 parts of aconitum carmichaeli, 3-5 parts of cape jasmine fruit, 5-10 parts of cassia bark, 5-15 parts of doubleteeth pubescent angelica root, 5-10 parts of castor seed, 5-10 parts of manchurian wildginger, 3-5 parts of raw nux vomica, 10-20 parts of field thistle herb, and 10-20 parts of pine nodule. The prescription has the effects of warming channel for dispelling cold, dissipating masses and detumescence, and dispelling stasis and relieving pain, and is beneficial to repair and regeneration of articular chondrocytes. The medicinal effect experiment shows that the pharmaceutical composition of the invention can obviously reduce the content of IL-1 and TNF-alpha in the synovial fluid, reduces synovial inflammation, and also has significant analgesic effects, and indicates that the pharmaceutical composition has relatively good therapeutic effects on arthritis.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a pharmaceutical composition for preventing and treating arthritis and a preparation method thereof. Background technique [0002] The etiology of arthritis is not yet fully clear, and the clinical manifestations are redness, swelling, heat, pain, dysfunction and joint deformity of the joints as the main symptoms. At present, the chemical drugs commonly used in the treatment of arthritis are mainly non-steroidal anti-inflammatory drugs, including ibuprofen, aspirin, diclofenac, etc. limit its clinical use. Contents of the invention [0003] In order to solve the above problems, the present invention provides a pharmaceutical composition for preventing and treating arthritis and a preparation method thereof. The obtained pharmaceutical composition has good curative effect and has no obvious side effects and adverse reactions. [0004] In order to achiev...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P19/02A61P19/08A61P29/00
CPCA61K36/15A61K36/185A61K36/232A61K36/237A61K36/268A61K36/28A61K36/328A61K36/47A61K36/54A61K36/56A61K36/59A61K36/714A61K36/744A61K36/9066A61K2236/15A61P19/02A61P19/08A61P29/00A61K2300/00
Inventor 杨锋
Owner SHAANXI UNIV OF CHINESE MEDICINE
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