Design method for improving detection performance of wearable and stretchable electrochemical sensor

Abstract

The invention discloses a design method for improving the detection performance of a wearable and stretchable electrochemical sensor. The method comprises: obtaining a design parameter matrix interpolation combination through orthogonal test design, and obtaining performance indexes of WSES under different tensile strengths through electrochemical experiments; establishing a nonlinear regression model corresponding to each performance index; simultaneously searching for a Pareto non-dominated optimal solution of the performance indexes by using a multi-objective optimization method to obtain aWSES design result; and carrying out optimization design on the wearable and stretchable electrochemical sensor according to the WSES design result. According to the design method, the relationship between other design parameters and the tensile strength can be considered, so that the optimal individuals in a non-dominated state can fully reflect the influence of different tensile strengths on the WSES performance, and the optimal performance under different tensile strengths is ensured. The problem that an existing WSES design method is insufficient in robustness to tensile strength is solved.

Description

technical field [0001] The invention relates to the field of electrochemical sensors, in particular to a design method for improving the detection performance of wearable and stretchable electrochemical sensors. Background technique [0002] In recent years, wearable electrochemical sensors (Wearable Electrochemical Sensor, WES) have attracted much attention and made great progress. Sweat, which contains abundant clinically relevant biomarkers, is one of the most suitable biological fluids for continuous monitoring. Traditional screen-printed electrode (Screen-Printed Electrode, SPE) sweat sensors are based on textile substrates, which limit the amount of skin detectable. There are also strict requirements on the selection of textile materials, these two factors will greatly affect the performance of sweat detection and limit the flexibility of the sensor. Durability and stability are two other challenges, so based on polymer (Polymeric) substrates become a new research of ...

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Problems solved by technology

[0005] In view of the above deficiencies in the prior art, the purpose of the present invention is to provide a design method for improving the detection performance of wearable and stretchable electrochemical sensors, aiming at solving the problem of insufficient robustness of the existing WSES design method for tensile strength

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