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Toothpaste for diminishing inflammation and alleviating pain

An anti-inflammatory, analgesic and toothpaste technology, applied in the field of daily necessities, can solve problems such as poor experience and affect users' use, and achieve the effects of shortening the healing time, high safety, and reducing pain.

Inactive Publication Date: 2020-01-31
汉源县昊业花椒产业研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

CN107334708A discloses a natural anti-inflammatory and analgesic toothpaste, which consists of 6-12 parts of comfrey, 6-12 parts of arctium, 6-12 parts of catechu, 2-4 parts of mint, 30-40 parts of baking soda, 4 parts of pearl powder -8 parts, 3-5 parts of vitamin D, 3-5 parts of vitamin C, 8-16 parts of sea salt, 10-20 parts of vegetable glycerin, 0.05-0.1 parts of organic essential oil, although the toothpaste does not add chemical preservatives, it can also remove Oral bacteria, more anti-inflammatory, hemostatic, analgesic effects, but still have the same problem as CN108635310A
However, if the Zanthoxylum bungeanum extract is directly used in the production of toothpaste, the numbing substance in the Zanthoxylum bungeanum will definitely bring a bad experience during use, and the toothpaste added with Zanthoxylum bungeanum extract will lose its Precipitation occurs. Although we have repeatedly performed homogenization during the experiment, after 6 months of observation, we found that there are still precipitates in the toothpaste, which affects the use of users.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] An anti-inflammatory and analgesic toothpaste

[0040] (1) Preparation of Zanthoxylum bungeanum extract:

[0041] ① Grind fresh Zanthoxylum bungeanum with liquid nitrogen, and freeze it for later use to obtain Zanthoxylum bungeanum sample tissue powder;

[0042] ② Add analytical pure methanol to the Zanthoxylum bungeanum sample tissue powder, 240V 40kHz ultrasonic leaching for 20min, centrifuge at low temperature at 7°C, collect the supernatant, continue to extract the residue 3 times under the same conditions, combine the three extracts, and dry them by rotary evaporation Reconstitute with methanol-water solution with a volume concentration of 15% (v / v);

[0043] ③ Gradually extract the reconstituted extract: first extract with analytical pure petroleum ether and reconstituted extract at a volume ratio of 1:1, keep the methanol water phase, and then use analytical pure dichloromethane and methanol water The phase is extracted at a volume ratio of 1:1, and the dichlor...

Embodiment 2

[0052] An anti-inflammatory and analgesic toothpaste

[0053] (1) Preparation of Zanthoxylum bungeanum extract:

[0054] ① Grind fresh Zanthoxylum bungeanum with liquid nitrogen, and freeze it for later use to obtain Zanthoxylum bungeanum sample tissue powder;

[0055] ②Add analytical pure methanol to the Zanthoxylum bungeanum sample tissue powder, 240V 40kHz ultrasonic leaching for 20min, centrifuge at 4°C, collect the supernatant, continue to extract the residue three times under the same conditions, combine the three extracts, and dry them by rotary evaporation Reconstitute with methanol-water solution with a volume concentration of 15% (v / v);

[0056] ③ Gradually extract the reconstituted extract: first extract with analytical pure petroleum ether and reconstituted extract at a volume ratio of 1:1, keep the methanol water phase, and then use analytical pure dichloromethane and methanol water The phase is extracted at a volume ratio of 1:1, and the dichloromethane phase i...

Embodiment 3

[0065] An anti-inflammatory and analgesic toothpaste

[0066] (1) Preparation of Zanthoxylum bungeanum extract:

[0067] ① Grind fresh Zanthoxylum bungeanum with liquid nitrogen, and freeze it for later use to obtain Zanthoxylum bungeanum sample tissue powder;

[0068] ② Add analytical pure methanol to the Zanthoxylum bungeanum sample tissue powder, 240V 40kHz ultrasonic leaching for 20min, centrifuge at 10°C to collect the supernatant, continue to extract the residue 3 times under the same conditions, combine the three extracts, and dry them by rotary evaporation Reconstitute with methanol-water solution with a volume concentration of 15% (v / v);

[0069] ③ Gradually extract the reconstituted extract: first extract with analytical pure petroleum ether and reconstituted extract at a volume ratio of 1:1, keep the methanol water phase, and then use analytical pure dichloromethane and methanol water The phase is extracted at a volume ratio of 1:1, and the dichloromethane phase i...

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PUM

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Abstract

The invention discloses toothpaste for diminishing inflammation and alleviating pain and a preparation method of the toothpaste. The toothpaste comprises raw materials of 3-9 parts of active components for diminishing inflammation and alleviating pain, 17-55 parts of an abrasive, 3-9 parts of a foaming agent, 12-36 parts of a wetting agent and an appropriate amount of water, wherein the raw materials of substances for diminishing inflammation and calming mainly comprise a Chinese prickly ash extract and a bunge pricklyash leaf extract. The substances for diminishing inflammation and calming prepared from the Chinese prickly ash and bunge pricklyash leaves are added to a toothpaste substrate, and when the substances for diminishing inflammation and calming are in contact with auxiliary materials, sufficient complexing can be performed, and adhesiveness and filming properties can be provided for the toothpaste. In the using process, the toothpaste can be adhered to the mucous membrane ofa mouth, a film can be formed, the durable effect of resisting bacteria can be achieved, and the gum is protected. The toothpaste can improve the oral environment, besides, can prevent gum bleeding and can refresh tone. Secondly, the prepared toothpaste for diminishing inflammation and alleviating pain can effectively reduce the pain feeling of patients suffering from dental ulcer, can shorten the healing time of the dental ulcer, and has notable protection effects on the mouth. The toothpaste is high in stability of effective components, and is relatively ideal healthy toothpaste.

Description

technical field [0001] The invention relates to the field of daily necessities, in particular to a preparation method of an anti-inflammatory and analgesic toothpaste and the anti-inflammatory and analgesic toothpaste prepared by the method. Background technique [0002] Medically, the soft tissue that surrounds and covers the teeth is called gingiva, and the acute and chronic inflammation that occurs in gingival tissue is called gingivitis. The clinical manifestations of gingivitis are bleeding, redness, and pain in the gums, and continue to develop and invade hard tissues, resulting in periodontitis, including inflammation of the gum tissue and manifestations of systemic diseases in the gums. Gingivitis is one of the most common human diseases. According to incomplete survey statistics, people suffering from gingivitis account for more than 80% of the total population in my country. Mild gingivitis is more common among adolescents and adults. If it is not detected early, t...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61Q11/00A61Q17/00A61K36/758A61P29/00A61P1/02
CPCA61K8/9789A61Q11/00A61Q17/005A61P29/00A61P1/02A61K36/758A61K2800/28A61K2800/82A61K2800/805A61K2300/00
Inventor 赵志峰何强何宗昊邬昊曦靳岳
Owner 汉源县昊业花椒产业研究院
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