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Calcium and vitamin-D chewable tablet and preparation method

A technology for vitamins and chewable tablets, which is applied in pharmaceutical formulations, active ingredients of aluminum/calcium/magnesium, and medical preparations with non-active ingredients, etc. The effect of large particle size, high quality and uniform particle size distribution

Inactive Publication Date: 2020-01-17
上海儿童营养中心(海南)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Calcium carbonate is the most widely used calcium supplement on the market. On the one hand, because calcium carbonate is weakly alkaline, it dissolves and releases calcium ions in the gastric juice in the body. Long-term use can cause indigestion and abdominal distension due to the consumption of gastric acid.
On the other hand, it is an inorganic compound, white solid, tasteless, odorless, neutral, essentially insoluble in water, and less absorbent than L-calcium lactate
[0005] Although L-calcium lactate has the above-mentioned advantages, L-calcium lactate itself has a bitter taste, and its taste is not easy to be accepted when it is made into calcium supplements

Method used

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  • Calcium and vitamin-D chewable tablet and preparation method
  • Calcium and vitamin-D chewable tablet and preparation method
  • Calcium and vitamin-D chewable tablet and preparation method

Examples

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no. 1 example

[0040] The calcium-vitamin D chewable tablet of this embodiment is proportioned according to the following weight ratio components.

[0041]

[0042]

[0043] of which vitamin D per gram 3 Combination powder contains 175mg of sucrose, 40mg of sodium ascorbate, vitamin D 3 2.5mg, caprylic acid glyceride 30mg, silicon dioxide 12mg, dl-α-tocopherol 10mg and sodium starch octenyl succinate 730.5mg.

[0044]The preparation method of the calcium vitamin D chewable tablet provided in this example comprises the following steps: S1: weighing ingredients; S2: granulating; S3: drying; S4: mixing; S5: tablet pressing; S6: inner packaging; S7 : outer packaging;

[0045] Specifically, in S1, vitamin D was weighed 3 Combination powder, L-calcium lactate, calcium hydrogen phosphate, D-mannitol, citric acid, sweet orange essence, magnesium stearate, sucralose, povidone K30, use containers or material bags for the weighed materials Pack it, seal it, and affix a material label on the o...

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Abstract

The invention provides a calcium and vitamin-D chewable tablet and a preparation method. The calcium and vitamin-D chewable tablet is prepared from, by weight, 211.28 parts + / -1% of calcium hydrophosphate, 207.22 parts + / -1% of L-calcium lactate pentahydrate, 0.63 parts + / -1% of vitamin D3, 730.35 parts + / -1% of D-mannitol, 20.00 parts + / -1% of citric acid, 14.40 parts + / -1% of magnesium stearate,3.32 parts + / -1% of povidone, 0.80 part + / -1% of sucralose, and 12.00 parts + / -1% of sweet orange essence. The chewable tablet has flavor suitable for most of people; sticking in tableting is avoidedduring preparation, so that the tablet prepared is smooth and not easy to crack.

Description

technical field [0001] The invention relates to a medicine or health food for supplementing human nutrients, in particular to a calcium vitamin D chewable tablet and a preparation method thereof. Background technique [0002] L-Calcium Lactate is bio-fermented organic calcium, and its absorption rate is higher than other calcium supplement products. After L-Calcium Lactate enters the intestinal tract, the free lactic acid changes the pH value of the intestinal lumen, inhibiting the growth of E. coli in the colon , the amount is reduced, the blood ammonia is reduced, and it is beneficial to health. Due to the left-handed characteristic of L-calcium lactate, it blends with the left-handed physiological characteristics of the human body, and the neutral pH value stabilizes, maintains, and promotes the formation of a healthy intestinal environment. , Contribute to the normal growth of intestinal dominant bacteria and exert their functions. [0003] L-calcium lactate is soluble ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/06A61K9/20A61K47/26A61K47/32A61K47/12A61P3/02A23L33/16A23L33/155A23L27/00A23L29/30A61K31/19A61K31/593
CPCA61K33/06A61K31/19A61K31/593A61K9/0056A61K9/2018A61K9/2013A61P3/02A23L33/16A23L33/155A23L27/00A23L29/30A23L29/37A23V2002/00A61K2300/00A23V2200/30A23V2200/16A23V2250/1578A23V2250/7106
Inventor 李红艳邓文峰刘海琼李思睿张海玲符晓霞王昱翔
Owner 上海儿童营养中心(海南)有限公司
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