Ginseng stem and leaf total saponin vaginal expansion suppository and preparation method and application thereof

Abstract

The present invention provides a ginseng stem and leaf total saponin vaginal expansion suppository and a preparation method and an application thereof. The ginseng stem and leaf total saponin vaginalexpansion suppository has an inner and outer two-layer structure, the outer layer comprises pharmaceutically active ingredients and a matrix, and the pharmaceutically active ingredients are antibiotics, safflowers and raspberries; and the inner layer comprises an expanded inner core and ginseng stem and leaf total saponins covered on the expanded inner core. After the ginseng stem and leaf total saponin vaginal expansion suppository reaches lesion sites, the pharmaceutically active ingredients in the outer layer are released first, have broad-spectrum microorganism-preventing and microorganism-killing ability, and have calming and anti-inflammatory functions of the lesion sites; the inner-layer ginseng stem and leaf total saponins are subsequently released and promote colonization and growth of beneficial micro-organisms in the vagina to rebuild vaginal microecological balance; and four drug components are sequentially released in a specific release order and cooperate with each other,so that the ginseng stem and leaf total saponin vaginal expansion suppository kills pathogenic micro-organisms, reconstructs a healthy vaginal microecological environment from the root, has high therapeutic efficiency and low recurrence rate for treatment of fungal vaginitis and bacterial vaginitis, and achieves radical cure of the vaginitis.

Description

technical field [0001] The invention belongs to the field of vaginal suppositories, and relates to a ginseng stem and leaf total saponin vaginal expansive suppository, a preparation method and application thereof. Background technique [0002] In recent years, the incidence of gynecological diseases has been very high. Most women have vaginal diseases to varying degrees. Candida vaginitis in women of childbearing age is a common gynecological disease, mainly manifested as vulvar itching and white vaginal discharge. The incidence rate Second only to trichomonal vaginitis, and the disease will recur. The improvement of the vaginal environment of women of childbearing age is of great significance to the health of women themselves and the birth of healthy offspring. [0003] Clotrimazole, metronidazole and other antibiotic spectrum antibacterial drugs are used to treat vaginitis caused by Candida, and have good antibacterial effects on various fungi. [0004] CN103830198A disc...

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Problems solved by technology

[0006] However, in the prior art, although vaginal medication containing antibiotics such as clotrimazole and metronidazole can have a good antibacterial effect on various fungi, and has curative effect on the treatment of vaginitis, it will affect the vaginal The environment causes harm, it has a killing effect on harmful bacteria, and it also has a killing effect on beneficial bacteria, which is not conducive to maintaining the normal flora environment in the vagina

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