Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Platelet-rich gel and preparation method thereof

A platelet-rich and platelet-rich plasma technology, applied in the field of platelet-rich gel and its preparation, can solve the problems of poor treatment effect and long ulcer healing time, and achieve the effects of shortening time, reducing pain and avoiding irritation.

Inactive Publication Date: 2020-01-10
内江市第一人民医院
View PDF4 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the above-mentioned deficiencies in the prior art, the present invention provides a platelet-rich gel and a preparation method thereof. The platelet-rich gel can effectively solve the poor therapeutic effect of existing drugs in the treatment of diabetic ulcers, and the ulcer healing long time problem

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Platelet-rich gel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A kind of platelet-rich gel, its preparation method comprises the following steps:

[0025] (1) Configuration of EDTA sodium salt solution: get sterilized water for injection, add sodium bicarbonate therein, adjust the pH value of sterilized water for injection to 7.5, then add EDTA sodium salt therein, Mix evenly to obtain an ethylenediaminetetraacetic acid sodium salt solution with a molar concentration of 0.2mol / L;

[0026] (2) Use a container containing EDTA sodium salt solution to collect peripheral venous blood from the patient. When the volume ratio of EDTA sodium salt solution in the container to the collected blood is 1:8, stop the collection, and then Put the container into a centrifuge and centrifuge at a speed of 2500r / min for 3min, then transfer the upper layer of plasma and the liquid 1mm below the plasma to another centrifuge tube, centrifuge the centrifuge tube at a speed of 4000r / min for 5min, discard the upper supernatant to obtain platelet-rich plasm...

Embodiment 2

[0030] A kind of platelet-rich gel, its preparation method comprises the following steps:

[0031] (1) Configuration of EDTA sodium salt solution: get sterilized water for injection, add sodium bicarbonate to it, adjust the pH value of sterilized water for injection to 8.2, then add EDTA sodium salt therein, Mix evenly to obtain an ethylenediaminetetraacetic acid sodium salt solution with a molar concentration of 0.5mol / L;

[0032] (2) Use a container containing EDTA sodium salt solution to collect peripheral venous blood from the patient. When the volume ratio of EDTA sodium salt solution in the container to the collected blood is 1:12, stop the collection, and then Put the container into a centrifuge and centrifuge at a speed of 2500r / min for 4min, then transfer the upper layer of plasma and the liquid 1mm below the plasma to another centrifuge tube, centrifuge the centrifuge tube at a speed of 4000r / min for 7min, discard the upper supernatant to obtain platelet-rich plasma...

Embodiment 3

[0036] A kind of platelet-rich gel, its preparation method comprises the following steps:

[0037] (1) Configuration of EDTA sodium salt solution: get sterilized water for injection, add sodium bicarbonate to it, adjust the pH value of sterilized water for injection to 7.8, then add EDTA sodium salt therein, Mix evenly to obtain an ethylenediaminetetraacetic acid sodium salt solution with a molar concentration of 0.25mol / L;

[0038] (2) Use a container containing EDTA sodium salt solution to collect peripheral venous blood from the patient. When the volume ratio of EDTA sodium salt solution in the container to the collected blood is 1:10, stop the collection. Then put the container into a centrifuge and centrifuge at a speed of 2500r / min for 4min, then transfer the upper plasma and the liquid 1mm below the plasma to another centrifuge tube, centrifuge the centrifuge tube at a speed of 4000r / min for 6min, discard supernatant, to obtain platelet-rich plasma;

[0039] (3) Get t...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a platelet-rich gel and a preparation method thereof. The preparation method comprises the following steps that an ethylenediamine tetracetic acid sodium solution is prepared,specifically, sterile water for injection is taken, sodium bicarbonate is added into the sterile water, the pH value of the sterile water for injection is adjusted to 7.8, then ethylenediamine tetracetic acid sodium is added into the mixture and mixed evenly, and the ethylenediamine tetracetic acid sodium solution with the molarity being 0.25 mol / L is prepared; peripheral venous blood of a patientis collected by a container containing the ethylenediamine tetracetic acid sodium solution, centrifugation is conducted, and platelet-rich plasma is prepared; thrombin lyophilized powder and calciumgluconate with the mass concentration being 10% are taken, and the thrombin lyophilized powder and the calcium gluconate are mixed evenly according to the ratio of 1ml of 10% calcium gluconate for every 1000 U of the thrombin lyophilized powder, and a thrombin solution is prepared. The platelet-rich plasma is prepared by mixing the platelet-rich plasma and the thrombin solution according to the volume ratio of 10:1; and the platelet-rich plasma and the thrombin solution are mixed evenly according to the volume ratio of 10:1, and the platelet-rich gel is prepared. According to the platelet-richgel, the therapeutic effect is good, and wound healing can be effectively promoted, and treatment time is shortened.

Description

technical field [0001] The invention relates to the technical field of platelet-rich gel, in particular to a platelet-rich gel and a preparation method thereof. Background technique [0002] With social progress and changes in people's lifestyles and diets, the incidence of diabetes is increasing year by year. According to a recent epidemiological study in China, the prevalence of diabetes in China has reached 9.7%, which is higher than the world average of 6.4%. Diabetic patients due to peripheral neuropathy and peripheral vascular disease combine excessive mechanical pressure, which can cause damage and deformity of the soft tissue and bone joint system of the foot, and then cause a series of foot problems, from mild neurological symptoms to severe ulcers , infection, vascular disease, Charcot arthropathy, and neuropathic fractures. If aggressive treatment does not adequately address the symptoms and complications that develop in the lower extremities, the consequences c...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/06A61K47/02A61K31/198A61K38/48A61P3/10A61P17/02
CPCA61K9/0014A61K9/06A61K31/198A61K38/4833A61K47/02A61P3/10A61P17/02C12Y304/21005A61K2300/00
Inventor 甘华葵陈军饶莉苏红陈燕刘斌伍璞姚俊玲范芳
Owner 内江市第一人民医院
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com