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Temperature control micro-valve based on liquid crystal and single-stage and multi-stage control systems thereof

A single-stage control and control system technology, applied in the direction of fluid controllers, laboratory containers, laboratory appliances, etc., can solve the problems of difficult processing and integration, difficult precise control, harsh use conditions, etc., to achieve Good dynamic response performance, low processing difficulty and low cost

Active Publication Date: 2019-12-24
CHONGQING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of this, the object of the present invention is to provide a temperature-controlled microvalve based on liquid crystal and its single and multi-level control system, aiming at the complex structure, difficult processing and integration, high cost, and use conditions existing in the prior art. Harshness, unresponsiveness, and difficulty in precise control, etc., the present invention realizes the runoff adjustment of samples through the asymmetric flow characteristics of liquid crystals in a non-uniform temperature field, thereby controlling the injection volume of different reactors or detectors, and significantly enhancing the chemical The comparative effect of the reaction or biological detection, but also greatly reduces the workload and related costs of experiments and detection

Method used

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  • Temperature control micro-valve based on liquid crystal and single-stage and multi-stage control systems thereof
  • Temperature control micro-valve based on liquid crystal and single-stage and multi-stage control systems thereof
  • Temperature control micro-valve based on liquid crystal and single-stage and multi-stage control systems thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0033] Such as figure 1 , A temperature-controlled microvalve based on liquid crystal, comprising a microchannel 1, a substrate 2, a liquid crystal and an electric heating wire 3; the microchannel 1 is arranged above the substrate 2; the liquid crystal is arranged in the microchannel 1 and can be along the channel direction Flow; The heating wire 3 is arranged outside the microchannel wall 4 on either side of the vertical liquid crystal flow.

[0034] The liquid crystal flows in from the inlet 7 of the microchannel 1 and flows out from the outlet 8, and the liquid crystal flows in different directions after flowing out from the outlet 8.

[0035] The heating wire can be arranged outside the microchannel wall 4 by bonding or other fixing methods.

[0036] When in use, by turning on the heating wire 3 to heat one side of the microchannel wall 4, the temperature of the liquid crystal in the microchannel 1 on this side rises, and there is a temperature difference between it and the other...

Embodiment 2

[0045] Such as image 3 The heating wire 3 and the cooling fins 5 are both block-type and independently controlled structures, which can control heating and cooling in blocks / sections, so as to control the temperature difference adjustment process more accurately and easily.

Embodiment 3

[0047] Such as Figure 4 The microchannel 1 may contain multiple subchannels superimposed up and down or left and right. The liquid crystal flows into the microchannel 1 from the inlet 7 and then flows into each subchannel respectively. The temperature control elements are simultaneously arranged in each subchannel of the microchannel 1. On the outside, in order to realize the multi-channel separate regulation of the flow in the microchannel.

[0048] On the basis of embodiment one, two or three, such as Figure 5 , A single-stage control system based on liquid crystal temperature-controlled microvalves. The control loop of the single-stage control system includes a temperature-controlled microvalve 9, temperature sensors and control elements. The liquid crystal flows out from the outlet of the temperature-controlled microvalve 9. The back flow is in different directions, namely a-direction channel and b-direction channel. The single-stage control system based on the liquid cryst...

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Abstract

The invention discloses a temperature control micro valve based on liquid crystal and single-stage and multi-stage control systems thereof, which are applied to the technical field of micro-fluidic chip micro valves; the temperature control micro valve comprises a micro-channel, a substrate, the liquid crystal and a temperature control element; wherein the micro-channel is arranged above the substrate; the liquid crystal is arranged in the micro-channel and can flow along the direction of the channel; the temperature control element is arranged on the micro-channel wall on any side vertical tothe liquid crystal flow direction; according to the invention, the runoff regulation of the sample is realized through the asymmetric flow characteristic of the liquid crystal under the non-uniform temperature field, so that the sample injection amount of different reactors or detectors is controlled, the comparison effect of chemical reaction or biological detection is remarkably enhanced, and the workload and related cost of experiments and detection are greatly reduced at the same time.

Description

Technical field [0001] The invention belongs to the technical field of microfluidic chip microvalves, and specifically relates to a liquid crystal-based temperature control microvalve and its single and multi-level control system. Background technique [0002] Microfluidic chip is also called Lab-on-a-Chip, which mainly realizes sampling, dilution, mixing, reaction, separation, analysis and detection in the chip by manipulating the fluid in the tiny channel And other laboratory functions. Microfluidic chips have the advantages of miniaturization, integration and portability. They can integrate the various functions of the analysis laboratory to the largest extent on a small chip. Therefore, it is used in many fields such as biology, medicine, materials, chemistry and chemical engineering. It has strong applicability and broad application prospects. [0003] The function of the microfluidic chip is to reliably control the fluid in the tiny channel to complete various operations re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
CPCB01L3/5027B01L3/502738B01L2200/0636B01L2300/1805B01L2300/1888B01L2300/1894B01L2400/0633
Inventor 于佳佳李谷元李友荣朱承志欧珂洁
Owner CHONGQING UNIV
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