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Sodium aescinate compound lozenge for treating oral ulcer and preparation method thereof

A technology for sodium aescinate and oral ulcers, which is applied in the field of sodium aescinate compound lozenges for the treatment of oral ulcers and its preparation, and can solve the problems of easy recurrence and large side effects

Inactive Publication Date: 2019-10-22
武汉长联来福制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, although the existing drug therapy has a certain effect, there are problems such as large side effects and easy recurrence.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Example 1: A sodium aescinate compound buccal tablet for the treatment of oral ulcers and a preparation method thereof, consisting of the following raw materials in parts by weight: 10 parts of sodium aescinate, vitamin B 2 10 parts, 15 parts of sweetener, 5 parts of essence, 20 parts of food binder, 2 parts of borneol, 4 parts of mannitol. The preparation method of the sodium aescin compound buccal tablet comprises the following steps: (1) taking each raw and auxiliary material and grinding it into fine powder, passing through a 100-mesh sieve for later use; (2) weighing each raw and auxiliary material fine powder and mixing (3) Weigh about 120 mg of the fine powder after mixing and press into tablets to make sodium aescinate compound buccal tablets. Clinical trials have proved that this product has the effects of anti-inflammation, detumescence, anti-exudation, promoting the dissolution and absorption of hematoma, and promoting the regeneration of oral cells, and can ...

Embodiment 2

[0018] Example 2: A sodium aescinate compound buccal tablet for the treatment of oral ulcers and a preparation method thereof, consisting of the following raw materials in parts by weight: 20 parts of sodium aescinate, vitamin B 2 40 parts, 2 parts of sweetener, 2 parts of essence, 10 parts of food binder, 4 parts of borneol, 6 parts of mannitol. The preparation method of the sodium aescin compound buccal tablet comprises the following steps: (1) taking each raw and auxiliary material and grinding it into fine powder, passing through a 100-mesh sieve for later use; (2) weighing each raw and auxiliary material fine powder and mixing (3) Weigh about 100 mg of the fine powder after mixing and press into tablets to make sodium aescinate compound buccal tablets. Clinical trials have proved that this product has the effects of anti-inflammation, detumescence, anti-exudation, promoting the dissolution and absorption of hematoma, and promoting the regeneration of oral cells, and can q...

Embodiment 3

[0019] Example 3: A sodium aescinate compound lozenge for the treatment of oral ulcers and a preparation method thereof, consisting of the following raw materials in parts by weight: 5 parts of sodium aescinate, vitamin B 2 30 parts, 10 parts of sweetener, 10 parts of essence, 5 parts of food adhesive, 2 parts of borneol, 4 parts of mannitol. The preparation method of the sodium aescin compound buccal tablet comprises the following steps: (1) taking each raw and auxiliary material and grinding it into fine powder, passing through a 100-mesh sieve for later use; (2) weighing each raw and auxiliary material fine powder and mixing (3) Weigh about 80 mg of the mixed fine powder and press it into tablets to make sodium aescinate compound buccal tablets. Clinical trials have proved that this product has the effects of anti-inflammation, detumescence, anti-exudation, promoting the dissolution and absorption of hematoma, and promoting the regeneration of oral cells, and can quickly an...

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PUM

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Abstract

The invention belongs to the technical field of medicine, and particularly relates to a sodium aescinate compound lozenge for treating oral ulcer and a preparation method thereof. The compound lozengeis composed of the following raw materials in parts by weight: 5-20 parts of sodium aescinate, 210-40 parts of vitamin B, 2-15 parts of a sweetener, 2-15 parts of flavor, 5-20 parts of a food binder,1 to 6 parts of borneol, and 1 to 6 parts of mannitol. The preparation method comprises the following steps: grinding the raw materials into fine powder and directly pressing the tablets by a powdertableting method. The compound lozenge has anti-inflammatory, detumescence, and anti-exudation functions, promotes the dissolution and absorption of the hematoma, and promotes the effect of oral cellregeneration. Compared with the prior art, the oral ulcer can be treated quickly and effectively, and the active ingredient is derived from the natural extract, and the side effects are small.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a sodium aescinate compound buccal tablet for treating oral ulcers and a preparation method thereof. The compound buccal tablet is composed of the following raw materials in parts by weight: 5-20 parts of sodium aescinate, vitamin B 2 10~40 parts, 2~15 parts of sweetener, 2~15 parts of essence, 5~20 parts of food adhesive, 1~6 parts of borneol, 1~6 parts of mannitol. The preparation method is as follows: the raw and auxiliary materials are ground into fine powder, and then directly compressed into tablets by a powder compression method. The present invention has the functions of anti-inflammation, detumescence, anti-exudation, promoting the dissolution and absorption of hematoma, and promoting the regeneration of oral cavity cells. Compared with the prior art, it can quickly and effectively treat oral ulcers. Small side effects. Background technique [0002] Sodiu...

Claims

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Application Information

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IPC IPC(8): A61K31/704A61K31/525A61K9/20A61P1/02
CPCA61K9/006A61K9/2054A61K31/525A61K31/704A61P1/02A61K2300/00
Inventor 徐刚刘大鹏刘早霞
Owner 武汉长联来福制药股份有限公司
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