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A sanitary napkin with antibacterial and soft properties

A technology for sanitary napkins and antibacterial peptides, applied in bandages, absorbent pads, medical science, etc., can solve the problems of low activity of antibacterial peptides, difficulty in finding antibacterial peptide models, etc. Effect

Active Publication Date: 2021-08-31
深圳市康乐美科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, it is difficult to find a unified model of antimicrobial peptides for extensive research
In addition, blindly using genetic engineering methods to express antimicrobial peptides without comprehensively discussing the structure, function, and in vivo and in vitro activities of antimicrobial peptides, resulting in most of the expressed antimicrobial peptides having low activity, or having hemolytic activity and cytotoxicity

Method used

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  • A sanitary napkin with antibacterial and soft properties
  • A sanitary napkin with antibacterial and soft properties
  • A sanitary napkin with antibacterial and soft properties

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The preparation of embodiment 1 antimicrobial peptide and antibacterial and hemolytic activity of antimicrobial peptide

[0026] The polypeptides of SEQ ID NO: 1 and 2 were prepared and obtained by artificial synthesis, and the specific preparation method was synthetically prepared by Shanghai Sangong Co., Ltd.

[0027] Determination of hemolytic activity: collect 1 mL of fresh blood from mice, dissolve it in 2 ml of PBS solution after anticoagulation with heparin, centrifuge at 1000 g for 5 min, and collect red blood cells; wash with PBS for 3 times, then resuspend with 10 ml of PBS; take 100 μL of red blood cell suspension and mix with Mix 100 μL of different concentrations of antimicrobial peptide solutions dissolved in PBS evenly, and incubate at a constant temperature in a 37°C incubator for 1h; take it out after 1h, and centrifuge at 4°C and 1000g for 5min; take out the supernatant and measure the light absorption value at 540nm with a microplate reader ; Take the...

Embodiment 2

[0028] The preparation of embodiment 2 antimicrobial polypeptide mycelia

[0029] Preparation of A chitosan solution: at room temperature, the chitosan with a viscosity-average relative molecular weight of 120,000 is dissolved in an acetic acid solution with a volume percent concentration of 90%, and a solution with a mass percent concentration of 7% is prepared, stirred 8 hours, obtain translucent brown chitosan acetic acid solution;

[0030] Preparation of B polyvinyl alcohol solution: 3500 degrees of polymerization and 88% degree of alcoholysis of polyvinyl alcohol are dissolved in deionized water to form a solution with a concentration of 10% by mass;

[0031] C mix above-mentioned chitosan solution and polyvinyl alcohol solution by mass ratio 5 / 1, obtain chitosan / polyvinyl alcohol complex solution;

[0032] Preparation of D chitosan / polyvinyl alcohol / SEQ ID NO: 1 polypeptide blend solution: add respectively to the above-mentioned chitosan / polyvinyl alcohol complex soluti...

Embodiment 3

[0034] The preparation of embodiment 3 antimicrobial polypeptide mycelia

[0035] Preparation of A chitosan solution: at room temperature, the chitosan with a viscosity-average relative molecular weight of 120,000 is dissolved in an acetic acid solution with a volume percent concentration of 90%, and a solution with a mass percent concentration of 7% is prepared, stirred 8 hours, obtain translucent brown chitosan acetic acid solution;

[0036] Preparation of B polyvinyl alcohol solution: 3500 degrees of polymerization and 88% degree of alcoholysis of polyvinyl alcohol are dissolved in deionized water to form a solution with a concentration of 10% by mass;

[0037] C mix above-mentioned chitosan solution and polyvinyl alcohol solution by mass ratio 5 / 1, obtain chitosan / polyvinyl alcohol complex solution;

[0038]Preparation of D chitosan / polyvinyl alcohol / SEQ ID NO: 2 polypeptide blend solution: add respectively to the above-mentioned chitosan / polyvinyl alcohol complex solutio...

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Abstract

The invention provides a relatively broad-spectrum antibacterial peptide for preparing antibacterial sanitary napkins, which not only can kill microorganisms in a broad spectrum, but also has good air permeability, and is suitable for large-scale popularization and application.

Description

technical field [0001] The invention belongs to the field of daily necessities, and in particular relates to a sanitary napkin with antibacterial and soft properties and a preparation method thereof. Background technique [0002] As a daily necessities for women, sanitary napkins are mainly composed of PE film, polymer composite paper, and polymer absorbers. Some sanitary napkins also have some special materials, such as refreshing factors containing menthol, houttuynia cordata and chlorhexidine. Thai and other Chinese and Western medicine ingredients, these ingredients have anti-inflammatory, detoxification, heat-clearing effects, and have a cool and comfortable feeling when used. At the same time, it can inhibit the growth of bacteria to a certain extent. [0003] At present, there are various styles and functions of sanitary napkins on the market. Sanitary napkins with a delicate smell, antibacterial effect and the ability to prevent and treat gynecological diseases have...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/46A61L15/32A61L15/28A61L15/24
Inventor 杨诗院余兵生张勇
Owner 深圳市康乐美科技有限公司
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