Chinese herbal medicine compound preparation for treating child vital myocarditis and preparation technology thereof

Abstract

The invention relates a Chinese herbal medicine compound preparation for treating child vital myocarditis and a preparation technology thereof, and belongs to the technical field of medicine application of effective Chinese herbal medicine parts. According to the technical scheme, the technology comprises the steps that American ginseng is smashed into coarse particles, ethyl alcohol is added forheating and reflux extraction three times, an extracted filtrate is concentrated through a rotary evaporator, the concentrated filtrate is extracted three time through equal volumes of petroleum etherand water-saturated n-butyl alcohol, a supernate is sampled, n-butyl alcohol inside the supernate is recycled through the rotary evaporator, remaining liquid medicine is subjected to water bath evaporation, after concentration, the product is placed into a drying box to be dried to obtain American ginseng total saponins; preparation methods of total saponins of Astragalus, total saponins of Moutan bark and total saponins of cowherb seeds are ditto; the mass ratio of total saponins of American ginseng to the total saponins of Astragalus to total saponins of Moutan bark to total saponins of cowherb seeds is 6:6:4:1. The bulk pharmaceutical chemicals are wide in source and low in cost; the preparation is remarkable in medicine effect, safe, free of toxin, small in medicine consumption and convenient for children to take, and the preparation is an oral medicine and is convenient to store.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating viral myocarditis in children and a preparation process thereof, especially for myocardial tissue damage and myocardial cell apoptosis caused by Coxsackie virus B (CVB) in enteroviruses. The application of the invention belongs to the technical field of medical application of effective parts of traditional Chinese medicines. Background technique [0002] Viral myocarditis (VMC) refers to localized or diffuse acute or chronic inflammatory lesions of the myocardium caused by viral infection, and belongs to infectious myocardial diseases. VMC has a wide range of people, and it is more common in preschool and school-age children. Most of them are caused by enteroviruses and respiratory viruses. Coxsackievirus A, Coxsackievirus B (CVB), Eikevirus, and poliovirus are common myocarditis-causing viruses, among which CVB is the most important pathogen, accounting for abou...

AI Technical Summary

Problems solved by technology

Western medicine treatment is mainly aimed at the symptomatic treatment of viral infection and myocardial inflammation. There are limited types of clinically available symptomatic therapeutic drugs for pediatric patients. Currently, free radical scavengers are mostly used in clinical practice, such as intravenous or oral vitamin C, coenzyme Q10, vitamin Bco , ATP, inosine, cyclic adenosine, cytochrome C, glucocorticoids, etc., but the treatment effect is not ideal, often have different degrees of adverse reactions, and the price is expensive

Although Chinese medicine literature has recorded many compound prescriptions to treat this disease, the curative effect is not good, and the clinical application dose is relatively large, especially there are shortcomings of large doses of traditional Chinese medicine taken by children and difficulty in application, and its mechanism of protecting the myocardium needs further research and confirmation, so It is particularly urgent to study the effective components of traditional Chinese medicine for the treatment of refractory diseases

Images