Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of birch mushroom extract in preparing preparation for treating and/ or preventing intestinal flora disorder and related diseases

An intestinal flora imbalance and extract technology, which is applied in metabolic diseases, allergic diseases, nervous system diseases, etc., can solve problems such as confusion in the scope of functions and market promotion, unclear quality control indicators of functional factors, and insufficient functions. , to achieve the effect of improving various physiological and pathological indicators related to immunity, contributing to the diversification of flora, and obvious therapeutic and/or preventive effects

Inactive Publication Date: 2019-05-21
GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY +1
View PDF5 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the improvement of the health quality of consumers, there is an even greater demand for refined health products. However, most of the existing edible and medicinal fungus health products have a confusing range of functions and market promotion. Functional factors and quality control indicators are not clear, and the functions are not significant enough. Medicinalization, therefore, there is an urgent need for more definite functional factors (active sites), a quality control system with medicinal effects and precision

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of birch mushroom extract in preparing preparation for treating and/ or preventing intestinal flora disorder and related diseases
  • Application of birch mushroom extract in preparing preparation for treating and/ or preventing intestinal flora disorder and related diseases
  • Application of birch mushroom extract in preparing preparation for treating and/ or preventing intestinal flora disorder and related diseases

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0050] In the fifth aspect of the present invention, there is provided a preparation method of Chaga antler extract, comprising: after crushing Chaga antler fruit bodies, sequentially extracting with alcohol, water, and NaOH alkaline water to obtain extraction solutions respectively, and then After concentration and freeze-drying respectively, chaga alcohol extract, chaga water extract and chaga alkali extract are obtained.

[0051] Preferably, a preparation method of Chaga antler extract comprises: after crushing Chaga antler fruit bodies, sequentially extracting with 95% ethanol, water, and 1%-2% NaOH alkaline water to obtain extraction solutions respectively, Then respectively concentrate and freeze-dry to obtain chaga alcohol extract, chaga water extract and chaga alkali extract.

[0052] Preferably, a preparation method of Chaga antler extract comprises: after chaga fruit bodies are pulverized, extraction is carried out by ethanol reflux to obtain a first filter residue a...

Embodiment 1

[0066] Embodiment 1: the preparation of chaga extract, the steps are as follows:

[0067] (1) Take chaga fruiting body raw material, use ethanol with a solid-liquid ratio of 1:8-1:15, reflux extraction for 2-4 hours, filter with suction, obtain filtrate, concentrate under reduced pressure to obtain a thick paste of appropriate concentration, thick The paste was frozen overnight at -80°C, and then dried in a freeze dryer to obtain the alcoholic extract of chaga.

[0068] (2) Take the filter residue after alcohol extraction of the above (1), use water with a solid-liquid ratio of 1:8-1:15, reflux extraction for 1-3 hours, and suction filter to obtain the filtrate, and concentrate under reduced pressure to obtain the appropriate concentration Thick paste, the thick paste is frozen overnight at -80°C, and dried in a freeze dryer to obtain the water extract of chaga.

[0069] (3) Take the filter residue extracted from the above (2) by alcohol and water, use water with a material-t...

Embodiment 2

[0073] Example 2: The improvement effect of chaga extract on the indicators related to intestinal flora imbalance in mice induced by high-fat diet

[0074] 1. Reagents:

[0075] Total cholesterol (T-CHO) test kit: Nanjing Jiancheng Institute of Bioengineering.

[0076] Triglyceride (TG) test kit: Nanjing Jiancheng Institute of Bioengineering.

[0077] Low-density lipoprotein cholesterol (LDL-C) test kit: Nanjing Jiancheng Bioengineering Institute.

[0078] High-density lipoprotein cholesterol (HDL-C) test kit: Nanjing Jiancheng Bioengineering Institute.

[0079] Thirty female C57 mice, SPF grade, weighing 12-14 g, and 28-30 days old, were purchased from Guangdong Medical Experimental Animal Center with license number SCXK (Guangdong) 2013-0002.

[0080] Rats and mice maintained feed: Guangdong Medical Experimental Animal Center, license number SCXK (Guangdong) 2013-0002.

[0081] The high-fat and high-cholesterol feed formula is shown in Table 2.

[0082]Table 2 Main comp...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to an application of an edible fungus extract in preparing a preparation for treating and / or preventing intestinal flora disorder and related diseases, in particular to an application of a birch mushroom extract in preparing a preparation for treating and / or preventing intestinal flora disorder and related diseases. The preparation method is simple and easy to implement, and low in operation cost; and an extraction solvent in the preparation method can be recycled, so that the residual risk of an organic reagent is avoided, the natural quality of the birch mushroom extract is ensured, and the method is environment-friendly, and belongs to a green manufacturing technology. According to the invention, the raw materials are completely extracted, the raw materials are fully utilized, and the utilization rate of the raw materials is high. The birch mushroom extract not only can obviously contribute to the recovery of the dominant flora structure in an intestinal tract and the diversity of a flora, but also has obvious treatment and / or prevention effects on diseases related to the flora structure of the intestinal tract, can be used in various fields such as medicines, health care products and the like, and has great economic and social values.

Description

technical field [0001] The present invention relates to the use of an edible fungus extract in the preparation of preparations for treating and / or preventing intestinal flora disorders and related diseases, in particular to the use of chaga extracts in the preparation of treating and / or preventing intestinal flora disorders The use in the preparation of disease and related diseases. Background technique [0002] In recent years, studies on gut microbiota have been emerging, and the role of gut microbiota in human health has attracted more and more attention. Gut flora is the sum of all microorganisms in the human intestinal tract. There are many types (including bacteria, fungi and viruses), and the number is even more amazing. It is estimated that in a normal adult, the total weight of intestinal bacteria can reach 1-1.5kg. They can affect body weight, digestion and absorption capacity, and resist the risk of infection and autoimmune diseases; in addition, they are also a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/07A61P1/00A61P37/04A61P3/06A61P3/04A61P31/04A61P29/00A61P37/08A61P25/00A61P35/00
Inventor 陈地灵唐晓萃郭殷锐吴清平谢意珍帅欧杨柏华
Owner GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com