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Bioactive glass (ceramic) material and casein phosphopeptide composition and application thereof in oral care products

A technology of casein phosphopeptide and bioactive glass, which is applied in the direction of drug combination, oral care, and cosmetic preparations, etc. It can solve problems such as inability to realize ready-to-use, influence of use effect, and reduced activity, and achieves deposition and regeneration. Improve mineralization efficiency, promote remineralization, and improve the effect of anti-dentin sensitivity

Inactive Publication Date: 2019-05-21
CHONGQING DENCARE CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Casein phosphopeptide belongs to a protein polypeptide segment, which is easily affected by pH and electrolyte ions generated by hydrolysis, resulting in reduced or inactivated activity
[0005] Most of the existing oral care products are water-containing systems, which is a test for the persistence of material activity, and the actual use effect of the products is affected
Moreover, existing oral care products cannot be ready-to-use

Method used

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  • Bioactive glass (ceramic) material and casein phosphopeptide composition and application thereof in oral care products
  • Bioactive glass (ceramic) material and casein phosphopeptide composition and application thereof in oral care products
  • Bioactive glass (ceramic) material and casein phosphopeptide composition and application thereof in oral care products

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Weigh the moisturizing agent, grinding agent, thickener and surfactant of the toothpaste respectively according to the following weight percentage (wt%).

[0051]

[0052]

[0053] The grinding agent of toothpaste can choose SiO2 colloid, calcium carbonate or calcium hydrogen phosphate. According to the process formula, first dissolve K12, PEG, and saccharin with glycerin in a pre-dissolving pot or a pre-mixing pot until uniform, add the powder into the paste pot, and then add the spices and stir with a scraper after the powder is added. , homogeneous stirring, grinding, and vacuuming at the same time. After passing the test, it is put into the paste storage pot for aging, and the filling is completed on the automatic filling line.

Embodiment 2

[0055] Weigh the moisturizing agent, grinding agent, thickener and surfactant of the toothpaste respectively according to the following weight percentage (wt%).

[0056]

[0057] The grinding agent of toothpaste can choose SiO2 colloid, calcium carbonate or calcium hydrogen phosphate. According to the process formula, first dissolve K12, PEG, and saccharin with glycerin in a pre-dissolving pot or a pre-mixing pot until uniform, add the powder into the paste pot, and then add the spices and stir with a scraper after the powder is added. , homogeneous stirring, grinding, and vacuuming at the same time. After passing the test, it is put into the paste storage pot for aging, and the filling is completed on the automatic filling line.

Embodiment 3

[0059] Weigh the moisturizing agent, grinding agent, thickener and surfactant of the toothpaste respectively according to the following weight percentage (wt%).

[0060]

[0061]

[0062] The grinding agent of toothpaste can choose SiO2 colloid, calcium carbonate or calcium hydrogen phosphate. According to the process formula, first dissolve K12, PEG, and saccharin with glycerin in a pre-dissolving pot or a pre-mixing pot until uniform, add the powder into the paste pot, and then add the spices and stir with a scraper after the powder is added. , homogeneous stirring, grinding, and vacuuming at the same time. After passing the test, it is put into the paste storage pot for aging, and the filling is completed on the automatic filling line.

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Abstract

The present invention provides a composition comprising a casein phosphopeptide and a bioactive material, and the bioactive material is a glass ceramic and / or a bioactive glass. The material can be made into oral care products of anhydrous system, such as an anhydrous toothpaste, mouthwash, tooth powder, a tooth gel, chewing gum, and the like. During use, the composition can effectively remineralize enamel and / or dentin damage, and block the ability to mask exposed dentin and / or cementum tubules; worn and / or etched enamel surfaces can be repaired; and the resistance of exposed and adjacent tooth structures to acid corrosion resistance to dentin sensitivity and caries prevention can be improved.

Description

technical field [0001] The invention belongs to the field of oral care products, and its application carrier can be toothpaste, tooth powder, tooth gel, chewing gum and the like. Background technique [0002] In recent years, with the improvement of living standards, people are more exposed to acidic substances and acidic beverages, which increases the risk of tooth erosion to varying degrees. In mild acid etching, the glaze surface softens, in severe cases, minerals fall off, and in severe cases, dentin is exposed, leading to caries, dentin sensitivity and other problems. [0003] Regarding the method of remineralization of enamel after acid etching, fluoride was mainly used in the early days. Studies have shown that silicon fluoride and silver fluoride have strong anti-caries ability, but acidic fluorophosphate and sodium fluoride cannot effectively prevent the dissolution of minerals in tooth enamel under acidic conditions, and the presence of too much fluoride ions will...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/25A61K8/81A61K8/34A61K8/86A61K8/19A61K8/26A61K8/24A61K8/46A61Q11/00A61P1/02A61P37/08
Inventor 董海德刘莉唐伟月张环邓全富邓嵘
Owner CHONGQING DENCARE CORP
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