Slow-release pain-easing antibacterial absorbable dressing and preparation method thereof
A slow-release, antibacterial activity technology, used in absorbent pads, rayon manufacturing, conjugated rayon, etc., can solve the problems of weak strength, poor antibacterial effect, no analgesic effect, etc., to prolong the release time, avoid burst effect
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Embodiment 1
[0031] A preparation method of slow-release analgesic antibacterial absorbable dressing, comprising the following steps:
[0032] (a) the preparation of spinning solution A: take chitosan and polylactic acid, add glacial acetic acid of 90wt% as solvent, be mixed with polymer total amount and be the mixed solution A of 5wt%, then described mixed solution A is in Reflux in a water bath at 90°C for 10 hours to fully dissolve it, then add the analgesic active drug bupivacaine into the mixed solution A, and magnetically stir until it dissolves and disperses evenly to obtain the spinning solution A; the chitosan and The mass ratio of the polylactic acid is 1:9; the mass fraction of the analgesic drug bupivacaine in the spinning solution A is 0.2wt%;
[0033] (b) Preparation of spinning solution B: take chitosan and polylactic acid in addition, add 90wt% glacial acetic acid as solvent, be mixed with the mixed solution B that the polymer total amount is 5wt%, then mix the mixed soluti...
Embodiment 2
[0038] A preparation method of slow-release analgesic antibacterial absorbable dressing, comprising the following steps:
[0039] (a) the preparation of spinning solution A: take chitosan and polylactic acid, add glacial acetic acid of 90wt% as solvent, be mixed with polymer total amount and be the mixed solution A of 5wt%, then described mixed solution A is in Reflux in a water bath at 90° C. for 10 hours to fully dissolve it, then add analgesic active drug lidocaine into the mixed solution A, and magnetically stir until it dissolves and disperses evenly to obtain a spinning solution A; the chitosan and the The mass ratio of the polylactic acid is 1:9; the mass fraction of the analgesic drug lidocaine in the spinning solution A is 0.3wt%;
[0040] (b) Preparation of spinning solution B: take chitosan and polylactic acid in addition, add 90wt% glacial acetic acid as solvent, be mixed with the mixed solution B that the polymer total amount is 5wt%, then mix the mixed solution B...
Embodiment 3
[0045] A preparation method of slow-release analgesic antibacterial absorbable dressing, comprising the following steps:
[0046] (a) the preparation of spinning solution A: take chitosan and polylactic acid, add glacial acetic acid of 90wt% as solvent, be mixed with polymer total amount and be the mixed solution A of 5wt%, then described mixed solution A is in Reflux in a water bath at 90°C for 10 hours to fully dissolve it, then add the analgesic active drug prilocaine into the mixed solution A, and magnetically stir until it dissolves and disperses evenly to obtain the spinning solution A; the chitosan and the The mass ratio of the polylactic acid is 1:9; the mass fraction of the analgesic drug prilocaine in the spinning solution A is 0.4wt%;
[0047] (b) Preparation of spinning solution B: take chitosan and polylactic acid in addition, add 90wt% glacial acetic acid as solvent, be mixed with the mixed solution B that the polymer total amount is 5wt%, then mix the mixed solu...
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