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Traditional Chinese medicine composition for treating chronic eczema and preparation method thereof

A technology of composition and traditional Chinese medicine, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve problems such as adverse reactions, pigmentation, and ineffective effects, and achieve satisfactory curative effect

Inactive Publication Date: 2019-02-12
马淑然
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Western medicine such as antihistamine cetirizine and hormone drugs only work on certain pathological links of chronic eczema, and there are many adverse reactions
In addition, long-term use of corticosteroids in the treatment of eczema can cause local telangiectasia, skin atrophy and pigmentation, and the effect tends to be less obvious with time

Method used

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  • Traditional Chinese medicine composition for treating chronic eczema and preparation method thereof
  • Traditional Chinese medicine composition for treating chronic eczema and preparation method thereof
  • Traditional Chinese medicine composition for treating chronic eczema and preparation method thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0067] (3) Preparation of particles

[0068] 1) Extract the volatile oil from nepeta, atractylodes atractylodes, tangerine peel, moutan bark, angelica, and uncaria medicinal materials in the prescription by steam distillation, and collect the distilled aqueous solution in another device, and use the dregs for later use.

[0069] 2) Add water to decoct the remaining medicinal materials such as medicinal residues and forsythia distilled in 1), soak for 20 to 60 minutes in water that is 2 to 8 times the total weight of medicinal materials for the first time, and then decoct for 1 to 2 hours. Two or three times, add 6 times the amount of water to decoct, each time for 1.5 hours, combine the decoction, and mix with the distilled aqueous solution in 1), concentrate until the ratio of the total amount of medicinal materials is 1:1.2 to 1.5, add an equal amount of 75% ethanol, settling for 24 hours, filtering the supernatant, recovering the ethanol, and concentrating to a thick paste ...

preparation Embodiment 1

[0085] Preparation Example 1, Chinese medicine granules

[0086] Raw material ratio:

[0087] Kochia chinensis 30g, white fresh skin 30g, Uncaria 30g, Morus alba 20g, Forsythia 20g, Sophora flavescens 20g, Smilax cocos 20g, Nepeta 10g, licorice 10g, dogwood 10g, atractylodes 10g, tangerine peel 10g, Moutan bark 10g , earthworm 10g, safflower 10g, cicada slough 10g, aconite 5g, appropriate amount of sucrose, appropriate amount of dextrin.

[0088] The nepeta, atractylodes, tangerine peel, moutan bark, angelica, and uncaria medicinal materials in the prescription are extracted by steam distillation, and the distilled aqueous solution is collected in another device, and the medicinal residue is used for later use.

[0089] Add water to decoct the distilled medicinal residues and forsythia and other remaining medicinal materials. For the first time, boil the boiling water with 8 times the total weight of the medicinal materials and decoct for 2 hours. Add 6 times the amount of wa...

preparation Embodiment 2

[0091] Preparation Example 2, Chinese medicine powder

[0092] Raw material ratio:

[0093] Kochia chinensis 30g, white fresh skin 30g, Uncaria 30g, Morus alba 20g, Forsythia 20g, Sophora flavescens 20g, Smilax cocos 20g, Nepeta 10g, licorice 10g, dogwood 10g, atractylodes 10g, tangerine peel 10g, Moutan bark 10g , earthworm 10g, safflower 10g, cicada slough 10g, aconite 5g.

[0094] Grind the above medicinal materials except aconite into fine powder and pass through a 60-mesh sieve; the aconite is separately crushed and passed through a 60-mesh sieve, and the powders obtained from the two are mixed uniformly by the method of increasing in equal amounts, and then packaged to prepare a powder.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating chronic eczema and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following bulk drugs in parts by mass: 3-10 parts of herba schizonepetae, 5-60 parts of fructus forsythia, 3-30 parts of radix aconiti lateralis praeparata, 3-30 parts of radix et rhizoma glycyrrhizae, 5-60 parts of cortex mori, 3-30 parts of fructus corni, 5-60 parts of radix sophorae flavescentis, 5-60 parts of rhizoma smilacis glabrae, 5-30 parts of rhizoma atractylodis, 3-30 parts of pericarpium citri reticulatae, 5-60 parts of cortex moutan, 3-30 parts of flos carthami, 5-60 parts of radix angelicae sinensis, 5-60 parts of fructus kochiae, 5-60 parts of cortex dictamni, 5-60 parts of pheretima, 5-60 parts of ramulus uncariae cum uncis and 3-30 parts of periostracum cicadae. The traditional Chinese medicine composition can be used for treating chronic eczema, phase I clinical trial shows that the traditional Chinese medicine composition has a good curative effect on treating chronic eczema, the total effective rate reaches 85.71%, and no obvious adverse reaction is observed.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating chronic eczema and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Eczema is a common allergic inflammatory skin disease, mainly caused by immune damage mediated by T cells. Clinically, it is characterized by the diversity of skin lesions, localized infiltration and hypertrophy of skin lesions in the chronic phase, severe pruritus, and easy recurrence. It often turns into chronic eczema due to repeated attacks of acute and subacute eczema, and chronic inflammation may also appear from the beginning. According to statistics, the prevalence rate of eczema among children in developed countries is as high as 30%, and the prevalence rate among adults is about 10%. Studies have shown that due to the rapid changes in the environment of rapid economic growth, the prevalence rate of eczema in developing countries...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K36/90A61K9/06A61K9/14A61K9/16A61K9/20A61P17/00A61P37/08A61K35/62A61K35/64
CPCA61K9/06A61K9/14A61K9/1652A61K9/2068A61K35/62A61K35/63A61K35/64A61K36/185A61K36/232A61K36/284A61K36/286A61K36/40A61K36/484A61K36/489A61K36/538A61K36/605A61K36/634A61K36/65A61K36/71A61K36/714A61K36/74A61K36/75A61K36/752A61K36/896A61K36/90A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61P17/00A61P37/08A61K2300/00
Inventor 马淑然陆锦锐肖延龄龙晓华成西刘雷蕾肖遥
Owner 马淑然
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