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Collagen for skin repairing and preparation method of collagen

A collagen and skin repair technology, applied in the field of peptide or protein preparation, can solve the problems of hidden safety concerns and doubts about the safety of collagen white, and achieve the effect of good solubility, high absorption, and increased content of active ingredients

Active Publication Date: 2018-12-28
艾苛密(上海)健康科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the collagen used in the market comes from the collagen tissue extracts of mammals or poultry animals such as cattle, pigs, and chickens. One after another, the safety of collagen white from livestock and poultry has been questioned, and some consumers have a tendency to be allergic to collagen from livestock
Therefore, the use of collagen extracted from terrestrial animals has potential safety concerns

Method used

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  • Collagen for skin repairing and preparation method of collagen
  • Collagen for skin repairing and preparation method of collagen

Examples

Experimental program
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Effect test

preparation example Construction

[0041] The preparation method of the ginger root extract is as follows: place the ginger root at 50° C. to dry for 6 hours, grind it to 40 meshes and then add it to 50 wt % ethanol aqueous solution, and the mass volume ratio of the ginger root to the 50 wt % ethanol aqueous solution is 1:8 ( g / mL), microwave treatment at 70°C and microwave power of 560W for 5 minutes, filtered through a 100-mesh filter cloth, and the obtained filtrate was placed in a rotary evaporator, concentrated at a temperature of 50°C and an absolute pressure of 0.05MPa Until the water content is 5%, the ginger root extract is obtained.

[0042] The preparation method of perilla leaf extract is as follows: dry perilla leaves at 50°C for 5 hours, crush them to a 40-mesh sieve, add 80wt% ethanol aqueous solution according to a solid-liquid ratio of 1:4, extract at 85°C for 3 hours, After filtering through a 150-mesh filter cloth, the resulting filtrate is concentrated in a rotary evaporator with a temperatu...

Embodiment 1

[0055] A preparation method of collagen for skin repair, comprising the following steps:

[0056] Ⅰ. Soak dried sea cucumbers in deionized water at 50°C, the mass ratio of deionized water to sea cucumbers is 15:1, take out after soaking for 10 hours, let it stand for 15 minutes, drain the water, and cut open the abdomen of sea cucumbers with scissors , remove the spit and wash the sea cucumbers with water at 20°C for 3 times, the mass ratio of water to sea cucumbers used for each washing is 2:1, to obtain pretreated sea cucumbers;

[0057] Ⅱ. Place the above-mentioned pretreated sea cucumbers in the meat grinding equipment at 20°C. The production capacity of the meat grinder is 120kg / h, and the power is 0.55kw. After grinding, the sea cucumbers with a diameter of 6mm are obtained. 1:10 (g / mL) Add deionized water to sea cucumber minced meat, stir at 20°C and 1500r / min for 30min to obtain a homogenate;

[0058] Ⅲ. add 0.5mol / L sodium hydroxide solution to above-mentioned homoge...

Embodiment 2

[0063] It is basically the same as Example 1, except that the deodorizing agent is prepared by mixing ginger root extract and perilla leaf extract in a mass ratio of 1:1.

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Abstract

The invention discloses collagen for skin repairing and a preparation method of the collagen. Sea cucumber is taken as a raw material and processed with an ultrahigh-pressure processing method and a protease enzymolysis method, meanwhile, an enzymatic hydrolysate is subjected to fishy smell removing treatment by a fishy smell removing agent, and therefore, the prepared collagen for skin repairingis high in active ingredient content, good in solubility, high in absorptivity and free of fishy smell, has multiple effects of oxidation resistance, inflammation resistance, DNA protective capability, moisturizing capability, anti-wrinkle property, skin whitening and the like and can be taken as the raw material to be applied to multiple fields of cosmetics, dietary supplements, food, medicine and the like.

Description

technical field [0001] The invention relates to a preparation method of peptide or protein, in particular to collagen for skin repair and a preparation method thereof. Background technique [0002] Collagen is an important functional protein. It has attracted widespread attention because of its strong biological activity and biological function. It has huge market potential and high economic value. It has been widely used in beauty care, medicine, food, and daily use. Chemical industry, biosynthesis, pharmaceutical capsules and other fields. [0003] At present, most collagen treatment methods include acid method, alkali method, enzymatic method, salt method and hot water extraction method, etc. Among them, the enzymatic method has mild conditions and less environmental pollution, which is superior. Most of the collagen used in the market comes from the collagen tissue extracts of mammals or poultry animals such as cattle, pigs, and chickens. One after another, the safety ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07K14/78C12P21/06A61K8/65A61Q19/00A61Q19/02A61Q19/08
CPCA61K8/65A61Q19/00A61Q19/02A61Q19/08C07K14/78C12P21/06
Inventor 张露引
Owner 艾苛密(上海)健康科技股份有限公司
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