Dual-optical frequency comb spectrum focusing coherent anti-stokes Raman scattering detection system

Abstract

A dual-optical frequency comb spectrum focusing coherent anti-stokes Raman scattering detection system comprises a dual-optical comb light source module, a stokes light generation module, a microscopyfocusing and sample scanning module, a sampling trigger module and coherent anti-stokes signal detection, acquisition and analysis processing module, wherein the dual-optical comb light source modulecomprises a path of optical frequency comb light source and the other path of optical comb light source, the path of optical frequency comb light source is used for as pumping light and detection light, the other path of optical comb light source is used as stokes light and is generated, tiny repeated frequency difference exists between the two paths of optical frequency comb light sources, the stokes light generation module is used for achieving optical frequency deviation by a fiber non-linear effect and acquiring the stokes light, and the sampling trigger module is used for acquiring a pulse coincidence position of two light combs by a secondary harmonic wave generation technology to achieve pulse positioning trigger spectrum acquisition. By the dual-optical frequency comb spectrum focusing coherent anti-stokes Raman scattering detection system, rapid wideband coherent anti-stokes Raman scattering detection without mechanical scanning is achieved, and the capability of a wideband coherent anti-stokes Raman scattering technology in high-dynamic and multi-constituent detection analysis application is remarkably improved.

Description

technical field [0001] The invention belongs to the technical field of coherent anti-Stokes Raman spectrum detection, in particular to a spectrum-focused coherent anti-Stokes Raman spectrum detection system through dual optical frequency comb optical inter-scanning and pulse chirp control. . Background technique [0002] Coherent Anti-Stokes Raman Spectroscopy (CARS: Coherent Anti-Stokes Raman Scattering) detection technology uses the third-order nonlinear effect, which can achieve higher detection sensitivity than the traditional spontaneous Raman process; at the same time, the CARS technology obtains the measured object The spectral signal corresponding to the intrinsic vibrational energy level of the molecule can achieve high specificity detection without the introduction of label signals. The above characteristics of CARS provide a new means for label-free imaging exploration in the fields of physical chemistry and life sciences. With the development of detection of co...

AI Technical Summary

Problems solved by technology

However, in the existing spectral focusing CARS technology, the relative time-delay scanning between pulses (equivalent to the detection of different Raman peaks) still relies on the scanning of the mechanical displacement platform, and the detection speed is slow, which cannot effectively exploit the potential of spectral focusing detection.

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