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Hippophae rhamnoides composition with effect of anti-coagulation, anti-platelet aggregation and anti-thrombus, and preparation method thereof

An anti-platelet aggregation and anti-thrombotic technology, which is applied in drug combinations, medical preparations containing active ingredients, food science, etc., to achieve the effects of lowering the extraction temperature, anti-coagulation, anti-platelet aggregation, and shortening the extraction time

Inactive Publication Date: 2018-12-18
BEIJING POWDERY FOOD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there is still a blank in the food therapy products, health products and quasi-literal drugs that use seabuckthorn seed proanthocyanidin extracts, scallion extracts, and fried perilla seed extracts for both medicine and food, anticoagulant, antiplatelet aggregation, and antithrombotic

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] (1) Weigh each material in proportion: 420 kg of seabuckthorn seed meal, 500 kg of scallion, and 480 kg of perilla seed.

[0024] (2) Preparation of seabuckthorn seed extract: Soak 420 kg of seabuckthorn seed meal with 8 times 65% ethanol for more than 1 hour; first ultrasonic extraction above 40°C for 30 minutes, second ultrasonic extraction for 20 minutes, 300-mesh filtration, combined Two extractions; low temperature (50°C) negative pressure (-0.098MPa) closed-loop heat pump evaporator unit recovers ethanol and concentrates the extract to a concentrate with a solid content of more than 40%; low temperature (50°C) negative pressure (-0.098MPa) Belt drying unit drying makes 42 kilograms of seabuckthorn seed extract powder for subsequent use;

[0025] (3) Preparation of Scallions extract: crush 500 kg of Scallions into particles larger than 20 mesh; soak in 10 times 80% ethanol for more than 1 hour; ultrasonically extract at 45°C for 30 minutes, filter at 300 mesh to ob...

Embodiment 2

[0031] (1) Weigh each material in proportion: 840 kg of seabuckthorn seed meal, 1000 kg of scallion, and 960 kg of perilla seed.

[0032] (2) Preparation of seabuckthorn seed extract: soak 840 kg of seabuckthorn seed meal with 8 times 65% ethanol for more than 1 hour; first ultrasonic extraction above 40°C for 30 minutes, second ultrasonic extraction for 20 minutes, 300-mesh filtration, combined Two extractions; low temperature (50°C) negative pressure (-0.098MPa) closed-loop heat pump evaporator unit recovers ethanol and concentrates the extract to a concentrate with a solid content of more than 40%; low temperature (50°C) negative pressure (-0.098MPa) 84 kilograms of sea-buckthorn seed extract powders were dried and prepared by belt drying unit for subsequent use;

[0033](3) Preparation of Scallions extract: crush 1,000 kg of Scallions into particles larger than 20 mesh; soak in 10 times 80% ethanol for more than 1 hour; ultrasonically extract at 45°C for 30 minutes, and fi...

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PUM

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Abstract

The invention discloses a Hippophae rhamnoides composition with effect of anti-coagulation, anti-platelet aggregation and anti-thrombus, and a preparation method thereof, and belongs to the field of preparation of dietary therapy products, health care products and drugs with State Drug Administration approval numbers, wherein the composition with medical and edible dual-purpose comprises, by weight, 20-45 parts of a Hippophae rhamnoides seed proanthocyanidin extract, 20-40 parts of an Allium macrostemon Bunge extract, and 20-45 parts of a fried Perilla seed extract. The preparation method comprises: extracting at a temperature (less than 50 DEG C), concentrating at a low temperature (less than 50 DEG C), and drying at a low temperature (less than 50 DEG C) so as to retain the biologicallyactive ingredients at a maximum. According to the present invention, the composition is made from the materials with medical and edible dual-purpose, such that the product is safe and can be taken fora long time; and the product can provide effects of anti-coagulation, anti-platelet aggregation and anti-thrombus, and is the safe and effective product for people with abnormal blood fat, abnormal blood viscosity, hyperlipidemia and hyperviscosity, and middle-aged and elderly people in the prevention of the occurrence of cardiovascular and cerebrovascular diseases and the prevention of the aggravation of cardiovascular and cerebrovascular diseases.

Description

Technical field: [0001] The invention relates to the fields of dietotherapy products, health care products and quasi-medicines, in particular to an anticoagulant, antiplatelet aggregation and antithrombotic seabuckthorn medicinal and edible variety composition and a preparation method. Background technique: [0002] At present, the number of cardiovascular and cerebrovascular diseases in my country has exceeded 300 million, and the number of patients is still on the rise, and the trend is younger! The annual incidence of coronary heart disease has exceeded 64‰. In the past five years, the number of people with cerebral apoplexy has been increasing at a rate of nearly 13% per year. In some areas, 40% of them are middle-aged people. A large number of experimental and clinical data show that the occurrence and development of cardiovascular and cerebrovascular diseases such as coronary heart disease, myocardial infarction, cerebral infarction, and deep venous thrombosis are clos...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P7/02A61P9/10
CPCA23L33/105A23V2002/00A61K36/185A61K36/535A61K36/8962A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00A23V2200/326A23V2250/21A23V2300/48
Inventor 邹玮
Owner BEIJING POWDERY FOOD
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