Microneedle patch used for resisting senility and removing wrinkles and preparation method of microneedle patch

A micro-needle sticker and needle technology, applied in the field of skin care products, can solve the problems of many adverse reactions, little anti-aging and wrinkle-removing effect, and large trauma, and achieve the effect of removing fine wrinkles, regulating cell metabolism, and small toxic and side effects.

Inactive Publication Date: 2018-11-30
XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although professional medical cosmetology has remarkable effects, it has the disadvantages of large trauma and many adverse reactions; self-use skin care products are usually mild in natur...

Method used

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  • Microneedle patch used for resisting senility and removing wrinkles and preparation method of microneedle patch
  • Microneedle patch used for resisting senility and removing wrinkles and preparation method of microneedle patch
  • Microneedle patch used for resisting senility and removing wrinkles and preparation method of microneedle patch

Examples

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Embodiment 1

[0033] An embodiment of the present disclosure provides a microneedle patch for anti-aging and anti-wrinkle, which includes a main body supporting component and a functional component. The main body supporting component constitutes a base and needles, and the functional components are dispersed in the base and the needles. The main support component is a hyaluronic acid solution made of biocompatible hyaluronic acid, and the functional components are composed of the following components by weight percentage: 10% ginseng extract, 15% centella asiatica extract , 5% seaweed extract, 10% licorice extract, 5% Tribulus terrestris extract, 10% green tea extract, 10% collagen, 10% donkey-hide gelatin, 8% glycerin, 5% vitamin E, 2% ascorbic acid, 5% allantoin and 5% Tween 60. The needles of the microneedle patch are pyramidal, conical or quasi-conical, the height of the needles is 50 μm, the base diameter is 50 μm, and the distance between the tips of two adjacent needles is 100 μm.

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Embodiment 2

[0041] An embodiment of the present disclosure provides a microneedle patch for anti-aging and anti-wrinkle, which includes a main body supporting component and a functional component. The main body supporting component constitutes a base and needles, and the functional components are dispersed in the base and the needles. The main support component is a pullulan solution made of biocompatible pullulan, and the functional components are composed of the following components by weight percentage: 30% ginseng extract, 25% centella asiatica extract , 3% seaweed extract, 5% licorice extract, 2% Tribulus terrestris extract, 5% green tea extract, 15% collagen, 5% donkey-hide gelatin, 5% glycerin, 2% ascorbic acid , 2% Tween 40 and 1% Tween 80. The needles of the microneedle patch are pyramidal, conical or quasi-conical, the height of the needles is 500 μm, the base diameter is 500 μm, and the distance between the tips of two adjacent needles is 1000 μm.

[0042] The preparation meth...

Embodiment 3

[0049] An embodiment of the present disclosure provides a microneedle patch for anti-aging and anti-wrinkle, which includes a main body supporting component and a functional component. The main body supporting component constitutes a base and needles, and the functional components are dispersed in the base and the needles. The main support component is a maltose solution made of biocompatible maltose, and the functional components are composed of the following components by weight: 20% ginseng extract, 20% centella asiatica extract, 5% Seaweed extract, 5% licorice extract, 5% Tribulus terrestris extract, 5% green tea extract, 15% collagen, 5% donkey-hide gelatin, 10% glycerin, 5% ascorbic acid, 2% Tween 20 and 3% squalene. The needle of the microneedle patch is pyramid-shaped, the height of the needle is 1000 μm, the base diameter is 1000 μm, and the distance between the tips of two adjacent quadrangular pyramid needles is 2000 μm, see figure 1 shown.

[0050] The preparatio...

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Abstract

The embodiment of the invention discloses a microneedle patch used for resisting senility and removing wrinkles and a preparation method of the microneedle patch, and relates to the field of skin careproducts. The microneedle patch comprises a main body support ingredient and a functional ingredient, wherein the main body support ingredient is manufactured by a degradable material with biocompatibility; and the functional ingredient is prepared from the following raw materials in percentage by weight: 10%-30% of ginseng extract, 15%-25% of centella extract, 3%-5% of seaweed extract, 5%-10% oflicorice extract, 2%-5% of tribulus terrestris extract, 5%-10% of green tea extract, 10%-15% of collagen, 5%-10% of colla corii asini, and 10%-25% of an auxiliary additive. The microneedle patch disclosed by the invention can effectively penetrate through the stratum corneum barrier of the skin, so that the functional ingredient directly reaches the dermis, then the metabolism of cells is rapidlyadjusted, the needed nutrient substances and collagen are supplemented, the texture state of the skin is improved, the efficacies of resisting senility and removing wrinkles are achieved, and in addition, the raw materials are natural and are small in toxic and side effects.

Description

technical field [0001] The present disclosure relates to the field of skin care products, in particular to a microneedle patch for anti-aging and anti-wrinkle and a preparation method thereof. Background technique [0002] The skin is composed of the epidermis, dermis and subcutaneous tissue. The dermis is very important in the aging process. It contains collagen and elastic fibers to form a complete three-dimensional fiber network. The former maintains the toughness of the skin, and the latter ensures the elasticity of the skin. the softness. These two important components, which are constantly produced by fibroblasts in the dermis, work together to make youthful skin elastic and wrinkle-free. But as we grow older, there will be problems with the metabolism of collagen and elastic fibers in the dermis. Their production will continue to decrease, and their decomposition will gradually accelerate. At the same time, the fat in the subcutaneous tissue will also gradually decre...

Claims

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Application Information

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IPC IPC(8): A61K8/98A61K8/9789A61K8/9706A61K8/65A61K8/02A61M37/00A61Q19/08
CPCA61K8/0204A61K8/0208A61K8/65A61K8/9706A61K8/9789A61K8/985A61M37/0015A61M2037/0046A61Q19/08
Inventor 陶娟杜虹瑶朱锦涛李钰策张连斌柳佩董励耘李军谢盈
Owner XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV
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