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Pharmaceutical composition for preventing and treating chicken coccidiosis

A chicken coccidiosis and composition technology, which is applied in the field of pharmaceutical compositions for preventing and treating chicken coccidiosis and its preparation, can solve the problems of drug residues, poor effect of anticoccidial drugs, and extensive drug resistance, and achieve enhanced Effects of resistance, reducing the amount of chicken bloody feces, and reducing damage

Inactive Publication Date: 2018-11-23
NANJING AGRICULTURAL UNIVERSITY +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The purpose of the present invention is to provide a kind of pharmaceutical composition for preventing and treating chicken coccidiosis aiming at the problems such as the poor effect of the current clinical coccidiostats, wide drug resistance and drug residues.

Method used

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  • Pharmaceutical composition for preventing and treating chicken coccidiosis
  • Pharmaceutical composition for preventing and treating chicken coccidiosis
  • Pharmaceutical composition for preventing and treating chicken coccidiosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Example 1: Preparation of a pharmaceutical composition for preventing and treating chicken coccidiosis

[0017] Add 1Kg of attapulgite and 1Kg of small leaf ground into 10L solution containing copper ions (0.1mol / L) and zinc ions (0.1mol / L), soak for 1h, boil for 1h, then filter with gauze, and discard the supernatant. , Dried naturally and then pulverized to obtain the pharmaceutical composition for preventing and treating chicken coccidiosis.

Embodiment 2

[0018] Example 2: Preventive effect on chicken coccidiosis

[0019] In a large-scale chicken farm, when the chickens are 10 days old, 6000 chickens are randomly selected and divided into 4 groups, each with 1500 chickens, and each group is raised separately. The first group: do not add any anti-coccidial drugs in the feed; the second group: add 5 g of the pharmaceutical composition for preventing and treating chicken coccidiosis per kilogram of feed; the third group: add 100 mg of monensin per kilogram of feed. Feeding to the age of 20 days, observe the mental state of the chickens in each group every day, check whether there is blood in the stool and count them, and perform necropsy on the sick and dead chickens to check whether there are coccidian oocysts in the intestinal contents. The results showed that the number of bloody stools in the first group was the largest. After the chicken died, 43 cases were confirmed to be infected by chicken coccidiosis by necropsy and egg obse...

Embodiment 3

[0020] Example 3: Therapeutic effect on chicken coccidiosis

[0021] The chicks are routinely raised until they are 14 days old and weighed one by one. They are divided into 8 groups, each with 15 chickens, and they are fed with corresponding feeds. Group A: Blank group, without any anticoccidial drugs in the feed; Group B: Add 10g of the drug composition for preventing and treating chicken coccidiosis per kilogram of feed; Group C: Add 10g of attapulgite per kilogram of feed; Group D: Add 10g per kilogram of feed; Add 10g of pulverized Diclazolin in one kilogram of feed; group E: add 1mg diclazuril per kilogram of feed; group F: 200mg copper sulfate and 200mg zinc sulfate per kilogram of feed; group G: add copper per kilogram of feed And zinc attapulgite (the preparation method of copper and zinc attapulgite: add 1Kg of attapulgite to 10L solution containing copper ion (0.1mol / L) and zinc ion (0.1mol / L), soak for 1h, and boil for 1h , Then centrifuge, wash the precipitate 3 tim...

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PUM

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Abstract

The invention provides pharmaceutical composition for preventing and treating chicken coccidiosis. The pharmaceutical composition is characterized by being prepared from the following ingredients of attapulgite, copper sulfate, zinc sulfate and stephania succifera root tuber. When the pharmaceutical composition for preventing and treating the chicken coccidiosis is added into a fodder, the chickenbloody excrement quantity is effectively reduced, the discharge quantity of excrement oocyst is reduced, damage caused by chicken coccidia to chicken intestinal tracts is alleviated, and immunity ofintestinal mucosa is enhanced. The pharmaceutical composition has a better effect of preventing and treating the chicken coccidiosis, and the effect can be achieved by independently adding all the components and anti-coccidia chemical diclazuril.

Description

Technical field [0001] The invention relates to a pharmaceutical composition for preventing and treating chicken coccidiosis and a preparation method thereof, in particular to an attapulgite, copper sulfate, zinc sulfate, and a medicinal composition for preventing and treating chicken coccidiosis, and The preparation method. Background technique [0002] Chicken coccidiosis is a global protozoal disease in chickens, and it is one of the most serious diseases in the chicken industry, and it is often epidemic. It has been listed by the United States Department of Agriculture as one of the five most serious diseases to poultry. It mainly harms chicks aged 15-50 days, the morbidity rate is as high as 50-70%, the mortality rate is 20-30%, and the severe cases reach 80%. The growth and development of chicks that have recovered from the disease are hindered and will not recover easily for a long time. Adult chickens are mostly insect carriers, and their weight gain and egg production...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/59A61P33/02A61K33/12A61K33/34A61K33/30
CPCA61K33/12A61K33/30A61K33/34A61K36/59A61K2300/00
Inventor 姚大伟杨德吉许莹
Owner NANJING AGRICULTURAL UNIVERSITY
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