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Soluble micro-needle patch drug delivery device

A drug delivery device and soluble technology, applied in the field of microneedles, can solve the problems of difference in thickness of stratum corneum, different user pressing force, poor user experience, etc., and achieve the effect of improving drug delivery efficiency and improving user experience

Pending Publication Date: 2018-11-06
YOUWE ZHUHAI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, when the existing dissolvable microneedle patch is applied, there are two problems as follows: first, the microneedle of the dissolvable microneedle patch dissolves and is absorbed by the skin relatively slowly, and generally takes 1-8 hours. The drug is fully absorbed by the skin, and the problem that the microneedle patch needs to be stuck on the skin surface for a long time has largely led to the poor actual use experience of the product; There are great differences in skin conditions and stratum corneum thickness, and different users have different pressing pressures. It is difficult for users to grasp the pressure suitable for their own skin to effectively penetrate the soluble microneedles into the skin, so that it is impossible to ensure that the drugs carried by the microneedles are truly absorbed by the skin. absorb

Method used

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  • Soluble micro-needle patch drug delivery device
  • Soluble micro-needle patch drug delivery device
  • Soluble micro-needle patch drug delivery device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] refer to figure 1 and figure 2 , this embodiment provides a dissolvable microneedle patch drug delivery device 1, including:

[0060] The main body assembly 11, and the microneedle drug introduction assembly 12 connected to the main body assembly 11; wherein,

[0061] The microneedle drug introduction assembly 12 includes a microneedle administration acceleration dissolving part 121 and a microneedle administration pressure sensing part 122;

[0062] One end of the microneedle administration acceleration dissolving part 121 is connected to the main body assembly 11, and the other end is connected to the microneedle administration pressure sensing part 122;

[0063] The microneedle administration pressure sensing part 122 includes a pressure sensing layer 1221 and a pressure sensor 1222 connected to the pressure sensing layer 1221;

[0064] The microneedle drug delivery pressure sensing part 122 is used to place a microneedle patch on the pressure sensitive layer 122...

Embodiment 2

[0077] refer to image 3 , based on the above-mentioned embodiment 1, this embodiment provides a dissolvable microneedle patch drug delivery device 1, wherein the main body assembly 11 includes a main body housing 111, and a processor 112 and a power supply provided in the main body housing 111 component 113;

[0078] As mentioned above, in order to ensure the service life of the device, the main body shell 111 can be made of a material with certain high temperature resistance or certain strength. Or, the material of high-hardness rubber with certain elasticity and the like.

[0079] The main body shell 111 can be in the shape of a hand grip, specifically, it can include a main body part that is snugly connected with the microneedle drug introduction assembly 12 and a handle part connected with the main body part, and the handle part has a shock-absorbing rubber material. Hand gel, or heat-insulating hand gel, prevents discomfort and burns on the arms caused by prolonged use...

Embodiment 3

[0096] refer to Figure 4 , based on the above-mentioned embodiment 2, this embodiment provides a dissolvable microneedle patch drug delivery device 1, wherein the microneedle drug delivery acceleration dissolving part 121 includes a heating unit 1211, an ultrasonic vibration unit 1212 and a microcurrent control unit 1213 one or more of them.

[0097] Preferably,

[0098] The heating unit 1211 includes a heating plate 12111, a temperature sensor 12112, and a heating control circuit 12113;

[0099] The heating plate 12111 is electrically connected to the heating control circuit 12113;

[0100] The temperature sensor 12112 is electrically connected to the heating control circuit 12113 and the processor 112 .

[0101] As mentioned above, the microneedle administration acceleration dissolving part 121 includes the heating unit 1211 . Wherein the heating unit 1211 includes a heating plate 12111 , a temperature sensor 12112 and a heating control circuit 12113 . The heating cont...

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Abstract

The invention provides a soluble micro-needle patch drug delivery device which comprises a main component and a micro-needle drug leading-in component connected with the main component. The micro-needle drug leading-in component comprises a micro-needle drug delivery accelerated dissolution portion and a micro-needle drug delivery pressure sensing portion, one end of the micro-needle drug deliveryaccelerated dissolution portion is connected with the main component, the other end of the micro-needle drug delivery accelerated dissolution portion is connected with the micro-needle drug deliverypressure sensing portion, the micro-needle drug delivery pressure sensing portion comprises a pressure sensing layer and a pressure sensor connected with the pressure sensing layer, the micro-needle drug delivery pressure sensing portion is used for placing a micro-needle patch on the pressure sensing layer, drugs are delivered to a drug delivery area through the micro-needle patch, and a drug delivery pressure value is acquired by the pressure sensor. According to the device, transdermal drug delivery is achieved by the soluble micro-needle patch through compression strength suitable for skins of a user, the drug delivery efficiency is improved in application process, drug components carried by a micro-needle is really absorbed by the skins, and user experience is improved.

Description

technical field [0001] The invention belongs to the field of microneedle technology, in particular to a dissolvable microneedle patch drug delivery device. Background technique [0002] Soluble microneedle technology is to conduct transdermal delivery of drugs through a soluble microneedle patch, which acts on the skin surface in a way similar to a Band-Aid. The drug delivery part of the soluble microneedle drug patch is composed of hundreds of soluble microneedles containing active drugs. The reason why the microneedles can be absorbed by the skin is that the material used to make the microneedles is very water soluble. When the microneedles pass through the skin The stratum corneum of the skin can naturally dissolve after contacting the moisture deep in the skin, so that the drug can be absorbed by the skin. [0003] At present, the use of dissolvable microneedle patches is all done by the user manually pasting the patch on the skin, and pressing the patch hard, so that t...

Claims

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Application Information

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IPC IPC(8): A61M37/00A61F9/00
CPCA61M37/0015A61M37/0092A61F9/0008A61M2037/0007A61M2037/0023A61M2037/0046A61M2037/0061A61M2205/3331
Inventor 不公告发明人
Owner YOUWE ZHUHAI BIOTECH CO LTD
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