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Postoperative wound anti-infection drug and preparation method thereof

An anti-infection and drug technology, applied in the field of medicine, can solve the problems of inconvenient use, poor bacteriostatic and bactericidal effect, and difficult to store, and achieve the effects of reducing infection rate, good detoxification and bacteriostasis, and easy to store and carry.

Inactive Publication Date: 2018-11-02
NANYANG CITY CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this invention only has a certain effect on the healing of the wound, and the antibacterial and bactericidal effect is poor, and it needs to be boiled to clean the wound surface, which is not easy to store, carry, and inconvenient to use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] A medicine for postoperative wound anti-infection is a liquid spray, which is prepared from the components in parts by weight shown in Table 1, and the dosage of each component in the extraction process of the bamboo leaf extract is shown in Table 2.

[0041] The extracting method of described bamboo leaf orchid extract, comprises the following steps:

[0042] S1: after drying and pulverizing Bambooleaf orchids, add ethanol solution with a volume fraction of 70% to soak for 1.5 hours, then heat and reflux for extraction at 65°C for 5 hours, and filter to obtain filter residue and filtrate 1;

[0043] S2: Dissolving α-cyclodextrin in water to form a cyclodextrin aqueous solution, placing the filter residue obtained in step S1 in the cyclodextrin aqueous solution, extracting at a constant temperature of 40°C for 3 hours, filtering, and collecting filtrate 2;

[0044] S3: Mix the filtrate 1 obtained in step S1 with the filtrate 2 obtained in step S2, stir at a speed of 200r / ...

Embodiment 2

[0052] A medicine for postoperative wound anti-infection is a liquid spray, which is prepared from the components in parts by weight shown in Table 1, and the dosage of each component in the extraction process of the bamboo leaf extract is shown in Table 2.

[0053] The extraction method of the Bamboo Phalaenopsis extract is the same as in Example 1, and the preparation method of the anti-infection medicine for postoperative wounds is the same as in Example 1.

Embodiment 3

[0055] A medicine for postoperative wound anti-infection is a liquid spray, which is prepared from the components in parts by weight shown in Table 1, and the dosage of each component in the extraction process of the bamboo leaf extract is shown in Table 2.

[0056] The extracting method of described bamboo leaf orchid extract, comprises the following steps:

[0057] S1: After drying and crushing Bamboo Phalaenopsis, add ethanol solution with a volume fraction of 72% to soak for 1.5 hours, then heat and reflux at 68°C for 4.5 hours, and filter to obtain filter residue and filtrate 1;

[0058] S2: Dissolving β-cyclodextrin in water to form a cyclodextrin aqueous solution, placing the filter residue obtained in step S1 in the cyclodextrin aqueous solution, extracting at a constant temperature of 45°C for 2.5 hours, filtering, and collecting filtrate 2;

[0059] S3: Mix the filtrate 1 obtained in step S1 with the filtrate 2 obtained in step S2, stir at a speed of 250r / min for 20m...

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Abstract

Belonging to the field of medical technology, the invention discloses a postoperative wound anti-infection drug and a preparation method thereof. The postoperative wound anti-infection drug is prepared from the following components by weight: 15-20 parts of an arundina graminifolia extract, 10-15 parts of mangnolia officinalis, 8-12 parts of phellodendron, 5-10 parts of peppermint oil, 2-5 parts of methyl violet, 5-8 parts of indigo naturalis, 16-19 parts of flaxseed oil, 8-11 parts of citric acid, and 35-42 parts of anhydrous ethanol. The anti-infection drug prepared according to the invention can effectively inhibit the production of bacterial toxin, reduce the postoperative wound infection rate, at the same time alleviate the wound pain, make the wound heal quickly, and reduce the generation of scars, and after being made into a spray, is convenient to preserve and carry, and is convenient to take.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a medicine for postoperative wound anti-infection and a preparation method thereof. Background technique [0002] Nosocomial infections include those that occur during hospitalization and those that occur after discharge from the hospital. Nosocomial infection brings serious harm to society and individuals. Surgery is a field with a high incidence of nosocomial infection, and wound infection in general surgery is one of the most common infections after surgery, and it accounts for a large proportion of nosocomial infections. Surgical incision infection is likely to cause poor wound healing, prolong the hospital stay, increase the pain and economic burden of patients, and even cause life-threatening in severe cases. Clinically, the infection rate of surgical incisions is often reduced from three aspects: preoperative preparation, aseptic operation during surgery, an...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K36/88A61K9/12A61P17/02A61P31/02A61K31/125A61K31/14
CPCA61K9/0014A61K9/12A61K31/125A61K31/14A61K36/195A61K36/315A61K36/534A61K36/55A61K36/575A61K36/704A61K36/756A61K36/88A61K36/898A61K47/12A61K2236/331A61K2236/333A61P17/02A61P31/02A61K2300/00
Inventor 朱金玉冀叶
Owner NANYANG CITY CENT HOSPITAL
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