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A traditional Chinese medicine composition used for treating ovarian cancer

A composition and technology for ovarian cancer, applied in the field of traditional Chinese medicine compositions for the treatment of ovarian cancer, can solve complex problems and achieve the effects of safe administration, tumor cell inhibition, and significant curative effect

Inactive Publication Date: 2018-10-16
山东大学深圳研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the mechanism of drug resistance in tumors is quite complex, for example, different tumor cells may have different drug resistance mechanisms to the same drug; and the same tumor may have multiple drug resistance mechanisms to the same drug.

Method used

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  • A traditional Chinese medicine composition used for treating ovarian cancer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] 1. Raw material composition:

[0047] 35 grams of Hedyotis diffusa, 25 grams of frankincense, 18 grams of Alisma, 25 grams of Chuanxiong, 25 grams of Sophora flavescens, 18 grams of white peony root, 18 grams of brown sugar, 35 grams of cinnamon, 35 grams of licorice, 35 grams of motherwort, 18 grams of solitary fern gram.

[0048] 2. Preparation method:

[0049] (1) Mix Hedyotis hundred flowers, frankincense and Alisma, pulverize, pass through an 80-mesh sieve, and pass through supercritical CO 2 Extraction, the extraction pressure is 28MPa, CO 2 The flow rate is 28L / h, the extraction time is 2h, the entrainer is 95% (volume fraction) ethanol, and the entrainer consumption is 8% of the total weight of the raw materials (Hedyotis liflora, Frankincense and Alisma) to obtain the plant extract;

[0050] (2) Grind Chuanxiong, Sophora flavescens, Radix Paeoniae Alba, brown sugar, cinnamon, licorice, motherwort, and Alpinia chinensis into powder and mix them by weight, or ...

Embodiment 2

[0055] Raw material composition:

[0056] 30 grams of Hedyotis diffusa, 30 grams of frankincense, 15 grams of Alisma, 30 grams of Rhizoma Chuanxiong, 20 grams of Sophora flavescens, 20 grams of white peony, 15 grams of brown sugar, 40 grams of cinnamon, 30 grams of licorice, 40 grams of motherwort, 15 grams of solitary fern gram.

[0057] The preparation method of the Chinese medicine composition is the same as in Example 1, and then prepared into granules in a conventional manner.

Embodiment 3

[0059] Raw material composition:

[0060] 40 grams of Hedyotis diffusa, 20 grams of frankincense, 20 grams of Alisma, 20 grams of Chuanxiong, 30 grams of Sophora flavescens, 15 grams of white peony root, 20 grams of brown sugar, 30 grams of cinnamon, 40 grams of licorice, 30 grams of motherwort, 20 grams of solitary fern gram.

[0061] The preparation method of the Chinese medicine composition is the same as Example 1, and then prepared into pills in a conventional manner.

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Abstract

The invention discloses a traditional Chinese medicine composition used for treating ovarian cancer. The composition comprises, by weight: 30-40 parts of hedyotis, 20-30 parts of frankincense, 15-20 parts of oriental waterplantain rhizome, 20-30 parts of Sichuan lovage rhizome, 20-30 parts of lightyellow sophora roots, 15-20 parts of debark peony root, 15-20 parts of brown sugar, 30-40 parts of Cortex Cinnamomi, 30-40 parts of liquorice roots, 30-40 parts of Herba Leonuri, and 15-20 parts of woolly grape fern. The composition is capable of suppressing tumor cells, reinforcing the vital essenceand strengthening the primordial qi, boosting immunity of patients, reducing pain of patients, improving life quality of patients and prolonging survival time of patients, and is low in side effect,simple to prepare and convenient to take. Raw materials are easily available, the price is low, and the traditional Chinese medicine composition is suitable for long-term taking of patients. Patientswith advanced ovarian cancer who have relapsed after postoperation chemotherapy, or who cannot tolerate chemotherapy, or who lose the chance of surgery, or who cannot tolerate surgery due to poor physical condition, can be treated by adopting the traditional Chinese medicine composition.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating ovarian cancer. Background technique [0002] Ovarian cancer is the female reproductive system tumor with the third highest incidence rate but the highest fatality rate. In 2008, there were 225,500 new cases and 140,200 deaths worldwide. Because the onset is insidious and the symptoms are not obvious, most patients have already reached the advanced stage when they are discovered. The 5-year survival rate of advanced ovarian cancer patients is only about 30-45%, and the prognosis is poor. At present, the clinical treatment of ovarian cancer is mainly surgical treatment, supplemented by comprehensive treatment of chemotherapy. However, in clinical treatment, many patients have difficulty in tolerating the toxic and side effects of chemotherapy due to their weak constitution after surgery, and it is diffi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/884A61P35/00A61K31/7016
CPCA61K31/7016A61K36/12A61K36/236A61K36/324A61K36/484A61K36/489A61K36/533A61K36/54A61K36/65A61K36/71A61K36/748A61K36/884A61K2236/331A61K2236/37A61K2236/39A61K2300/00
Inventor 苑存忠
Owner 山东大学深圳研究院
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