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Golden camellia oral liquid inhibiting alpha-glucosidase and preparation method thereof

A technology of glucosidase and camellia chrysalis, which is applied in the direction of medical formula, dispersion liquid delivery, medical preparations containing active ingredients, etc., can solve the problems of incurability, high morbidity, and small side effects, etc., and is easy to carry and easy to use , Improving the effect of immune function

Inactive Publication Date: 2018-10-12
DALIAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its clinical manifestations are polydipsia, polyphagia, polyuria, and emaciation as the main features, and it has the characteristics of high morbidity, many complications, and can not be cured
[0003] At present, there are few traditional Chinese medicines that can inhibit α-glucosidase, and compared with western medicines, traditional Chinese medicines have less side effects, so a Chinese medicine preparation that can inhibit α-glucosidase is needed to achieve its medicinal value

Method used

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  • Golden camellia oral liquid inhibiting alpha-glucosidase and preparation method thereof

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Effect test

Embodiment 1

[0026] A golden camellia oral liquid for inhibiting α-glucosidase, which is composed of the following raw materials: 20 parts of golden camellia, 15 parts of ghost arrow feather, 10 parts of native ginseng, 5 parts of Polygonatum odoratum, and 15 parts of licorice.

[0027] The preparation method of above-mentioned oral liquid comprises the following steps:

[0028] (1) Wash Camellia Camellia, Ghost Arrow Feather, Ginseng, Polygonatum Polygonatum, and Licorice according to their proportions, and dry them to obtain a mixture;

[0029] (2) Add the above mixture into water and carry out ultrasonic extraction for 3 times. The amount of water added for the first extraction is 12 times of the total volume of the medicine, the second time is 7 times of the total volume of the medicine, and the third time is 5 times of the total volume of the medicine. times; the combined extracts were concentrated under reduced pressure at 60-70°C until the relative density was 1.10 (measured at 60°C...

Embodiment 2

[0037] A golden camellia oral liquid for inhibiting α-glucosidase, which is composed of the following raw materials: 25 parts of golden camellia, 20 parts of ghost arrow feather, 12 parts of native ginseng, 8 parts of Polygonatum odoratum, and 17 parts of licorice.

[0038] The preparation method of above-mentioned oral liquid comprises the following steps:

[0039] (1) Wash Camellia Camellia, Ghost Arrow Feather, Ginseng, Polygonatum Polygonatum, and Licorice according to their proportions, and dry them to obtain a mixture;

[0040] (2) Add the above mixture into water and carry out ultrasonic extraction for 3 times. The amount of water added for the first extraction is 12 times of the total volume of the medicine, the second time is 7 times of the total volume of the medicine, and the third time is 5 times of the total volume of the medicine. times; the combined extracts were concentrated under reduced pressure at 60-70°C until the relative density was 1.10 (measured at 60°C...

Embodiment 3

[0048] A golden camellia oral liquid for inhibiting α-glucosidase, which is composed of the following raw materials: 35 parts of golden camellia, 26 parts of ghost arrow feather, 14 parts of native ginseng, 9 parts of Polygonatum odoratum, and 19 parts of licorice.

[0049] The preparation method of above-mentioned oral liquid comprises the following steps:

[0050] (1) Wash Camellia Camellia, Ghost Arrow Feather, Ginseng, Polygonatum Polygonatum, and Licorice according to their proportions, and dry them to obtain a mixture;

[0051] (2) Add the above mixture into water and carry out ultrasonic extraction for 3 times. The amount of water added for the first extraction is 12 times of the total volume of the medicine, the second time is 7 times of the total volume of the medicine, and the third time is 5 times of the total volume of the medicine. times; the combined extracts were concentrated under reduced pressure at 60-70°C until the relative density was 1.10 (measured at 60°C...

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Abstract

The invention relates to a traditional Chinese medicine composition, in particular to golden camellia oral liquid inhibiting alpha-glucosidase and a preparation method thereof. The oral liquid is prepared from, by weight, 20-45 parts of golden camellia, 15-30 parts of twigs of winged euonymus, 10-15 parts of panicled fameflower roots, 5-10 parts of radix polygonati officinalis and 15-20 parts of licorice roots. Accordingly, by means of reasonable compatibility of all traditional Chinese medicines, the oral liquid is obtained, carrying is facilitated, convenience is brought to use, the obviousinhibiting effect on alpha-glucosidase is achieved, and the oral liquid is suitable for large scale production and use.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a golden camellia oral liquid for inhibiting α-glucosidase and a preparation method thereof. technical background [0002] In recent years, the incidence of diabetes has been increasing year by year. According to statistics, one person dies of diabetes-related diseases every 10 minutes in the world. Diabetes has become the third major disease after cardiovascular and cerebrovascular diseases and cancer. In recent years, the research on diabetes has aroused the general attention of scholars at home and abroad. At present, the inhibition of postprandial blood glucose rise has been used as the main point of treatment for diabetes mellitus and impaired glucose tolerance. α-glucosidase inhibitors can inhibit the activity of α-glucosidase in the small intestine, delay or inhibit the absorption of glucose in the intestine, thereby effectively reducing postprandial hypergly...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61K9/08A61P3/10
CPCA61K9/0095A61K36/185A61K36/37A61K36/484A61K36/82A61K36/8969A61K2236/331A61K2236/39A61K2236/51A61K2236/55A61P3/10A61K2300/00
Inventor 于大永宋昱郭秀磊史丽颖
Owner DALIAN UNIV
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