A monoclonal antibody for recognizing monohydric phenolic compounds and its preparation method and application

A technology of monoclonal antibodies and monohydric phenols, applied in biochemical equipment and methods, chemical equipment and methods, microorganisms, etc.

Active Publication Date: 2021-06-11
JINAN TAIHE PHARM TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Currently commonly used tumor inducing factors include smoking, drinking, etc., but these risk factors cannot provide any scientific interpretation for the biological characterization of early tumor progression

Method used

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  • A monoclonal antibody for recognizing monohydric phenolic compounds and its preparation method and application
  • A monoclonal antibody for recognizing monohydric phenolic compounds and its preparation method and application
  • A monoclonal antibody for recognizing monohydric phenolic compounds and its preparation method and application

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Embodiment Construction

[0094] The present invention will be described in further detail below in conjunction with the accompanying drawings: the present embodiment is implemented on the premise of the technical solution of the present invention, and detailed implementation is provided, but the protection scope of the present invention is not limited to the following embodiments.

[0095] A monoclonal antibody that recognizes monohydric phenolic compounds, the nucleic acid sequence information of the heavy chain coding region of the monoclonal antibody is encoded by the DNA sequence shown in SEQ 1; the amino acid of the heavy chain coding region of the monoclonal antibody The sequence information is encoded by the amino acid sequence shown in SEQ 2;

[0096] The nucleic acid sequence information of the light chain coding region of the monoclonal antibody is encoded by the DNA sequence shown in SEQ 9; the amino acid sequence information of the light chain coding region of the monoclonal antibody is enc...

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Abstract

The present invention relates to a monoclonal antibody that recognizes monohydric phenol compounds. The nucleic acid sequence information of the heavy chain coding region is encoded by the DNA sequence shown in SEQ 1; the amino acid sequence information of the heavy chain coding region is the amino acid shown in SEQ 2 Sequence coding; the nucleic acid sequence information of the light chain coding region is coded by the DNA sequence shown in SEQ 9; the amino acid sequence information of the light chain coding region is coded by the amino acid sequence shown in SEQ 10. The monoclonal antibody for recognizing monohydric phenolic compounds described in the present invention can detect monohydric phenolic compounds in human body fluids, and the content of monohydric phenolic compounds can reflect the degree of cell activity in the body of the subject and the immunity of the body state, thus contributing to the early diagnosis of tumors. The monoclonal antibody for recognizing monohydric phenolic compounds of the present invention can effectively detect gastric cancer, colon cancer, rectal cancer, esophageal cancer, pancreatic cancer and other digestive tract tumors.

Description

technical field [0001] The invention relates to the field of monoclonal antibodies, in particular to a monoclonal antibody that recognizes monohydric phenolic compounds and its preparation method and application. Background technique [0002] Cancer has become the main cause of human death in the world. Most cancer patients are at an advanced stage when the cancer is diagnosed, and with the improvement of tumor progression, patients are always accompanied by a serious imbalance in nutritional status, which may seriously affect cancer. High morbidity and mortality among patients. Currently commonly used tumor inducing factors include smoking, drinking, etc., but these risk factors cannot provide any scientific interpretation for the biological characterization of early tumor progression. Tumor epidemiological survey data show that 45% of cancer patients lose more than 10% of their body weight, and 25% of cancer patients lose more than 20% of their body weight. In patients w...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07K16/44G01N33/574C12N5/20
CPCC07K16/44C07K2317/565G01N33/574
Inventor 李漪娜
Owner JINAN TAIHE PHARM TECH CO LTD
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