Lycium ruthenicum pure powder tablets and preparation method thereof
The technology of black wolfberry and black wolfberry powder is applied in the field of health care products, which can solve the problems of poor fluidity and high hygroscopicity, and achieve the effects of unique production method, changing fluidity and improving high hygroscopicity.
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Embodiment 1
[0033] The black wolfberry pure powder tablet of the present invention comprises 80g of black wolfberry powder, 19g of dextrin filler, 0.5g of lubricant talc, and 0.5g of silicon dioxide.
[0034] The preparation method of the present invention is as follows:
[0035] (1) The dried black wolfberry is crushed at a temperature not exceeding 40° C.; sieved with a 300-mesh sieve, and the particle size of the sieved black wolfberry is less than 50 μm to obtain black wolfberry powder, which is set aside;
[0036] (2) Granulation: add black wolfberry powder and filler according to the proportion, pass through a 20-mesh sieve, spray an appropriate amount of 5% pvp solution (prepared with 50% ethanol solution) or do not add it for wet granulation to obtain mixed granules;
[0037] (3) Drying Select the drying temperature of 40°C wet granules, and operate in an inert gas (nitrogen) environment; the ambient humidity is controlled at 40% RH, spread the wet granules on a baking tray, and p...
Embodiment 2
[0041] The black wolfberry pure powder tablet of the present invention is made of 85g of black wolfberry powder, 19.5g of mannitol filler, and 0.5g of talcum powder.
[0042] The preparation method of the present invention is as follows:
[0043] (1) The dried black wolfberry is crushed at a temperature not exceeding 40°C; sieved with a 300-mesh sieve, the particle size of the black wolfberry after sieving is less than 50 μm, and the black wolfberry powder is obtained for later use;
[0044] (2) Granulation: add black wolfberry powder and filler according to the proportion, pass through a 30-mesh sieve, spray into an appropriate amount of 5% pvp solution (prepared with 50% ethanol solution) or do not add wet granulation to obtain mixed granules;
[0045] (3) For drying, select the drying temperature of 30°C wet granules, and operate in an inert gas (carbon dioxide) environment; the ambient humidity is controlled at 40% RH, spread the wet granules on a baking tray, and put them...
Embodiment 3
[0049] The black wolfberry pure powder tablet of the present invention is made of 92g of black wolfberry powder, 7.5g of dextrin and hydroxymethyl cellulose, and 0.5g of silicon dioxide as a lubricant.
[0050] The preparation method of the present invention is as follows:
[0051] (1) The dried black wolfberry is crushed at a temperature not exceeding 40°C; sieved with a 400-mesh sieve, the particle size of the black wolfberry after sieving is less than 50 μm, and the black wolfberry powder is obtained for future use;
[0052] (2) Granulation: Add black wolfberry powder and filler according to the proportion, pass through a 25-mesh sieve, spray into an appropriate amount of 5% pvp solution (prepared with 50% ethanol solution) or do not add wet granulation to obtain mixed granules;
[0053] (3) Drying Select the drying temperature of 50°C wet granules, and operate in an inert gas (argon) environment; the ambient humidity is controlled at 40% RH, spread the wet granules on a ba...
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