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Pharmaceutical preparation for treating diabetic cardiomyopathy and preparation method thereof

A technology for diabetic cardiomyopathy and pharmaceutical preparations, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of not being too many, single treatment, etc., and achieves convenient operation, simple process, and wide source of raw materials. Effect

Inactive Publication Date: 2018-06-08
FOURTH MILITARY MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, neither traditional Chinese medicine nor Western medicine has a very good effect on the treatment of diabetic heart disease. Although there have been traditional Chinese medicines for the treatment of diabetic cardiomyopathy, there are not many such medicines, and the main drugs are phlegm-resolving prescriptions. By lowering serum total cholesterol, promoting low-density lipoprotein and fighting lipid plaque formation, this treatment is relatively simple, and more prescriptions for treating diabetic heart disease still need to be developed from different aspects

Method used

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  • Pharmaceutical preparation for treating diabetic cardiomyopathy and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036]A pharmaceutical preparation for treating diabetic cardiomyopathy, which is made of the following raw materials in parts by weight: 15 parts of medlar, 15 parts of schisandra, 15 parts of jujube seed, 13 parts of Shouwu vine, 15 parts of jujube, 15 parts of aralia taibai 10 parts of mulberry, 4 parts of ginseng, 10 parts of trichosanthes, 10 parts of Ophiopogon japonicus, 7 parts of Chuanxiong and 4 parts of coptis.

[0037] The preparation method of the pharmaceutical preparation for treating diabetic cardiomyopathy comprises the following steps:

[0038] S1. First, weigh the crude drug as required, add 12 times the weight of water to the crude drug, soak for 35 minutes, decoct for 1 hour, filter to obtain the first filtrate and filter residue, and set aside;

[0039] S2. Add 9 times the weight of water to the filter residue obtained in S1, decoct for 1 hour, and filter to obtain the second filtrate for use;

[0040] S3. Combine the first filtrate obtained in S1 and th...

Embodiment 2

[0044] A pharmaceutical preparation for treating diabetic cardiomyopathy, made of the following raw materials in parts by weight: 10 parts of medlar, 10 parts of schisandra, 10 parts of jujube seed, 10 parts of Shouwu vine, 10 parts of jujube, 10 parts of aralia taibai 8 parts, 8 parts of mulberry, 3 parts of ginseng, 8 parts of trichosanthes, 8 parts of Ophiopogon japonicus, 5 parts of Chuanxiong and 3 parts of Coptis chinensis.

[0045] The preparation method of the pharmaceutical preparation for treating diabetic cardiomyopathy comprises the following steps:

[0046] S1. First, weigh the crude drug as required, add 10 times the weight of water to the crude drug, soak for 30 minutes, decoct for 1 hour, filter to obtain the first filtrate and filter residue, and set aside;

[0047] S2. Add 8 times the weight of water to the filter residue obtained in S1, decoct for 1 hour, and filter to obtain the second filtrate for use;

[0048] S3. Combine the first filtrate obtained in S...

Embodiment 3

[0052] A pharmaceutical preparation for treating diabetic cardiomyopathy, which is made of the following raw materials in parts by weight: 20 parts of wolfberry fruit, 20 parts of schisandra chinensis, 20 parts of jujube seed, 15 parts of shouwu vine, 20 parts of jujube, 20 parts of aralia taibai 13 parts of mulberry, 5 parts of ginseng, 13 parts of trichosanthes, 13 parts of Ophiopogon japonicus, 10 parts of Chuanxiong and 5 parts of Coptis chinensis.

[0053] The preparation method of this kind of pharmaceutical preparation for the treatment of diabetic cardiomyopathy comprises the following steps:

[0054] S1. First, weigh the crude drug as required, add 15 times the weight of water to the crude drug, soak for 40 minutes, decoct for 1.5 hours, filter to obtain the first filtrate and filter residue, and set aside;

[0055] S2. Add 10 times the weight of water to the filter residue obtained in S1, decoct for 1.5 hours, and filter to obtain the second filtrate for use;

[005...

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Abstract

The invention discloses a pharmaceutical preparation for treating diabetic cardiomyopathy and a preparation method thereof. The pharmaceutical preparation is prepared from the following raw materialsin parts by weight: 10-20 parts of wolfberry, 10-20 parts of fructus schisandrae chinensis, 10-20 parts of semen ziziphi spinosae, 10-15 parts of caulis polygoni multiflori, 10-20 parts of Chinese dates, 10-20 parts of aralia taibaiensis, 8-13 parts of herba taxilli, 3-5 parts of ginseng, 8-13 parts of radix trichosanthis, 8-13 parts of radix ophiopogonis, 5-10 parts of rhizoma chuanxiong and 3-5parts of rhizoma coptidis. The preparation method of the pharmaceutical preparation comprises the following steps: decoction, mixing, concentration and spray drying. Compared with the prior art, the pharmaceutical preparation has the efficacies of reducing blood pressure and blood sugar, protecting cardiac muscles, easing pain, diminishing inflammation, regenerating body fluid, clearing heat, tonifying vital energy, nourishing yin, tonifying the spleen, the liver and the kidney and nourishing the heart; and the preparation method is simple, wide in raw material source and suitable for industrial large-scale production.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a pharmaceutical preparation for treating diabetic cardiomyopathy and a preparation method thereof. Background technique [0002] Diabetic cardiomyopathy (DCM) refers to myocardial disease that occurs in diabetic patients and cannot be explained by hypertensive heart disease, coronary atherosclerotic heart disease, valvular heart disease and other heart diseases. This is a complication of late diabetes, an independent and specific cardiomyopathy. With the increasing incidence of diabetes and the prolongation of the course of the disease, diabetic cardiomyopathy has become one of the main causes of death in diabetic patients. The initiating factor of DCM is abnormal myocardial energy metabolism, including decreased glucose and lactate metabolism, increased fat metabolism leading to the accumulation of free fatty acids and the resulting imbalance in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P9/00A61P3/10
CPCA61K36/185A61K36/236A61K36/25A61K36/258A61K36/428A61K36/57A61K36/704A61K36/718A61K36/725A61K36/79A61K36/815A61K36/8968A61K2300/00
Inventor 关月
Owner FOURTH MILITARY MEDICAL UNIVERSITY
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