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Intravesical instillation liquid for treating struvite urinary stone of pet dogs

A technology of bladder perfusion and canine ammonium phosphate, which is applied in the field of bladder perfusion solution, can solve the problems that the effect has not been paid attention to, and achieve the effects of avoiding large damage to animals, protecting the bladder mucosa, and avoiding easy recurrence

Active Publication Date: 2018-05-29
永春县产品质量检验所福建省香产品质量检验中心国家燃香类产品质量监督检验中心福建
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the role of chemical stone dissolution in preventing stone recurrence and dissolving small stones has not been paid attention to

Method used

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  • Intravesical instillation liquid for treating struvite urinary stone of pet dogs
  • Intravesical instillation liquid for treating struvite urinary stone of pet dogs
  • Intravesical instillation liquid for treating struvite urinary stone of pet dogs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The bladder perfusion solution for treating pet dog magnesium ammonium phosphate urolithiasis is composed of the following components by mass: 20 tea polyphenols, 6 g of sodium hyaluronate, 10 g of Imperata imperata root extract, 10 g of Murata extract, and 1000 ml of buffer medium . The buffer medium is composed of the following components in parts by mass: 10 g of citric acid monohydrate, 14 g of sodium citrate dihydrate, and 1000 ml of water for injection; the pH value of the buffer medium is 4.5-5.5.

[0028] The preparation method of the bladder perfusion solution for treating pet dog magnesium ammonium phosphate urolithiasis, the specific steps are as follows:

[0029] (1) Weigh tea polyphenols, sodium hyaluronate, extract of Imperata imperinae, and Gourilla japonica extract respectively according to the requirements; after fully pulverizing each component, filter with a 60-mesh sieve, fully mix, sterilize and seal for future use;

[0030] (2) Preparation of buff...

Embodiment 2

[0033] The bladder perfusion solution for treating pet dog magnesium ammonium phosphate urolithiasis consists of the following components in parts by mass: 30 parts by mass of tea polyphenols, 10 g of sodium hyaluronate, 15 g of Imperata imperata root extract, 15 g of Murasmus extract, and 1000 ml of buffer medium . The buffer medium is composed of the following components in parts by mass: 12 g of citric acid monohydrate, 16 g of sodium citrate dihydrate, and 1000 ml of water for injection; the pH value of the buffer medium is 4.5-5.5.

[0034] All the other are with embodiment 1.

Embodiment 3

[0036] The bladder perfusion solution for treating pet dog magnesium ammonium phosphate urolithiasis consists of the following components in parts by mass: 30 parts by mass of tea polyphenols, 8 g of sodium hyaluronate, 15 g of Imperata Rhizoma Imperatae extract, 15 g of Murasmus extract, and 1000 ml of buffer medium . The buffer medium is composed of the following components in parts by mass: 11 g of citric acid monohydrate, 14 g of sodium citrate dihydrate, and 1000 ml of water for injection; the pH value of the buffer medium is 4.5-5.5.

[0037] All the other are with embodiment 1.

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Abstract

The invention discloses an intravesical instillation liquid for treating struvite urinary stone of pet dogs and belongs to the medical field of pets. The intravesical instillation liquid is prepared from components by mass as follows: 20-30 g of tea polyphenol, 6-10 g of sodium hyaluronate, 10-15 g of a rhizoma imperatae extract, 10-15 parts of a common jasminorange leaf and twig extract and 1,000ml of a buffer medium. The buffer medium comprises components by mass as follows: 10-12 g of citric acid monohydrate, 14-16 g of trisodium citrate dihydrate and 1,000 ml of water for injection; the pH value of the buffer medium ranges from 4.5 to 5.5. The intravesical instillation liquid can improve the pH value of urine, promote litholysis and discharge, control urinary tract bacterial infection, protect bladder mucosa, stop bleeding and relieve pain caused by stone under the synergistic effect of all components. The intravesical instillation liquid is economical and convenient to operate and is a new generation of ideal chemical litholysis product for treating struvite stone.

Description

technical field [0001] The invention belongs to the pet medical field, and in particular relates to a bladder perfusion solution for treating pet dog magnesium ammonium phosphate urolithiasis. Background technique [0002] Dogs are the most intimate companion animals of humans, but due to reasons such as unscientific feeding and management, unbalanced diet and nutrition, canine magnesium ammonium phosphate urinary stones occur. The survey found that about 77.3% of the dogs had the same diet as the owner, and about 50.5% of the dogs were mainly offal (chicken liver, sheep liver), meat (chicken, pork) and rice. The ratio of phosphorus to calcium in these feeds is significantly higher than the feeding standard, and long-term feeding will cause an increase in the phosphorus excreted by dogs through the urinary tract; Too much dietary magnesium to maintain the dynamic balance of magnesium in the body; and because the protein in these feeds is particularly rich, the amount of amm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P13/04A61P13/10A61K31/728A61K31/353A61K31/194
CPCA61K9/0034A61K31/194A61K31/353A61K31/728A61K36/75A61K36/899A61K2300/00
Inventor 陆江朱道仙卢劲晔卢炜刘静陆峰贺林娜陈彦慧
Owner 永春县产品质量检验所福建省香产品质量检验中心国家燃香类产品质量监督检验中心福建
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