Oral gel containing radix-et-rhizoma-notoginseng rare saponin and preparation method thereof
The technology of rare saponins and Panax notoginseng is applied in the field of oral gel containing rare saponins of Panax notoginseng and the field of preparation thereof, which can solve problems such as product stability to be improved, achieve long-term bacteria blocking, enhance the effect of drugs, and enhance the use effect. Effect
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Embodiment 1
[0034] Embodiment 1, a kind of oral gel containing notoginseng rare saponins
[0035] The oral gel containing the rare saponins of Panax notoginseng consists of the following raw materials and their parts by mass:
[0036] 4 parts of Panax notoginseng rare saponin pre-mixed milk, 0.3 parts of chitosan oligosaccharide with an average molecular weight of 1000, 45 parts of glycerin, 12 parts of carbomer 981NF, 40717 parts of poloxamer, 8 parts of mint essence, 0.7 parts of ethyl paraben , 0.2 parts of disodium edetate, 5 parts of triethanolamine and 880 parts of purified water.
[0037] The preparation method of the Panax notoginseng rare saponin premixed milk is:
[0038](1) Crush Panax notoginseng and pass through a 20-mesh sieve to obtain Panax notoginseng powder, add petroleum ether with 4 times the mass of the above-mentioned Panax notoginseng powder, stir at a speed of 300r / min, stir for 4h, let stand for 1h, remove the upper liquid , add petroleum ether with 3 times the ...
Embodiment 2
[0046] Embodiment 2, a kind of oral gel containing the rare saponins of Panax notoginseng
[0047] The oral gel containing the rare saponins of Panax notoginseng consists of the following raw materials and their mass parts:
[0048] 6 parts of Panax notoginseng rare saponin pre-mixed milk, 0.5 parts of chitosan oligosaccharide with an average molecular weight of 3000, 55 parts of glycerin, 18 parts of carbomer 981NF, 40722 parts of poloxamer, 11 parts of mint essence, 1.2 parts of ethyl paraben , 0.4 parts of disodium edetate, 7 parts of triethanolamine and 900 parts of purified water.
[0049] The preparation method of the Panax notoginseng rare saponin premixed milk is similar to that of Example 1.
[0050] The preparation method of the oral gel containing the rare saponins of Panax notoginseng, the steps are as follows:
[0051] S1 Take carbomer, add purified water, the amount of purified water added is 28 times the mass of the above-mentioned carbomer, stir evenly, let s...
Embodiment 3
[0056] Embodiment 3, a kind of oral gel containing the rare saponins of Panax notoginseng
[0057] The oral gel containing the rare saponins of Panax notoginseng consists of the following raw materials and their mass parts:
[0058] 5 parts of Panax notoginseng rare saponin pre-mixed milk, 0.4 parts of chitosan oligosaccharide with an average molecular weight of 2000, 50 parts of glycerin, 15 parts of carbomer 981NF, 40720 parts of poloxamer, 10 parts of mint essence, 1 part of ethyl paraben , 0.3 parts of disodium edetate, 6 parts of triethanolamine and 892.7 parts of purified water.
[0059] The preparation method of the Panax notoginseng rare saponin premixed milk is similar to that of Example 1.
[0060] The preparation method of the oral gel containing the rare saponins of Panax notoginseng, the steps are as follows:
[0061] S1 Take carbomer, add purified water, the amount of purified water added is 26 times the mass of the above-mentioned carbomer, stir evenly, let st...
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