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Preparation method of Jinguanyin tea essence and application thereof in preparation of anti-tumor medicines

An anti-tumor drug, the technology of Golden Guanyin, which is applied in the field of medicine and food, can solve the problems of rare activity evaluation and application, and the anti-tumor mechanism remains to be explored, and achieves industrialization expansion and commercial application, enhanced extraction efficiency, and high economic value. Effect

Pending Publication Date: 2018-04-13
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Through literature search, it is found that commercially available tea-containing foods, health care products or the application of related tea extracts are mainly developed for anti-radiation (CN102552549A), blood lipid lowering (CN106039111A, CN106912789A), blood sugar lowering (CN102960500B, CN101961426B), etc. Nutrients, beverages (CN101848647B, CN102138598B), flavors (CN100553469C), cosmetics, and food and medicine for improving immunity (CN106266253A); Tumor mechanism of action remains to be explored

Method used

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  • Preparation method of Jinguanyin tea essence and application thereof in preparation of anti-tumor medicines
  • Preparation method of Jinguanyin tea essence and application thereof in preparation of anti-tumor medicines
  • Preparation method of Jinguanyin tea essence and application thereof in preparation of anti-tumor medicines

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Experimental program
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Effect test

Embodiment 1

[0051] The extraction of embodiment 1 Jinguanyin tea essence

[0052] Weigh 500 grams of Jinguanyin summer tea and autumn tea leaves in traditional Chinese medicine cans, add 15 times the volume of deionized water for the first time, add 10 times the volume of deionized water for the second time, extract twice at 100 ° C, and extract for the first time The time is 1.5h, the second extraction time is 1h, the filtrate is sieved through 100 mesh, and the two filtrates are combined; then the two extractions are transferred to a double-effect concentration tank, the vacuum concentration temperature of the concentration tank is 75 ° C, and the vacuum degree is -0.04MPa ~-0.07Mpa, concentrate until the sugar content of Jinguanyin tea extract is 25; finally move the concentrated solution into a centrifugal spray dryer, control the inlet air temperature to 170°C, and the outlet air temperature to 90°C, and the dried Jinguanyin tea extract Moisture content ≤ 6% can be. The total extrac...

Embodiment 2

[0053] The extraction of embodiment 2 Jinguanyin tea essence

[0054] Weigh 500 grams of Jinguanyin summer tea and autumn tea leaves in traditional Chinese medicine tanks, add 30 times the volume of deionized water for the first time, add 25 times the volume of deionized water for the second time, extract twice at 100 ° C, and extract for the first time The time is 1.5h, the second extraction time is 1h, the filtrate is sieved through 100 mesh, and the two filtrates are combined; then the two extractions are transferred to a double-effect concentration tank, the vacuum concentration temperature of the concentration tank is 75 ° C, and the vacuum degree is -0.04MPa ~-0.07Mpa, concentrate until the sugar content of Jinguanyin tea extract is 25; finally move the concentrated solution into a centrifugal spray dryer, control the inlet air temperature to 170°C, and the outlet air temperature to 90°C, and the dried Jinguanyin tea extract Moisture content ≤ 6% can be. The total extra...

Embodiment 3

[0055] The extraction of embodiment 3 Jinguanyin tea essence

[0056] Weigh 500 grams of Jinguanyin tea leaves in a traditional Chinese medicine tank, add 25 times the volume of deionized water for the first time, add 15 times the volume of deionized water for the second time, extract twice at 100 °C, the first extraction time is 1.5h, and the second time The first extraction time is 1h, the filtrate is sieved through 100 mesh, and the two filtrates are combined; then the two extractions are transferred to a double-effect concentration tank, the vacuum concentration temperature of the concentration tank is 75 °C, the vacuum degree is -0.04MPa~-0.07Mpa, and the concentration Until the sugar content of Jinguanyin tea extract is 25; finally the concentrated solution is moved into a centrifugal spray dryer, the air inlet temperature is controlled to be 170°C, the outlet temperature is 90°C, and the moisture content of Jinguanyin tea extract after drying is ≤6%. Can. The total ext...

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Abstract

The invention discloses a preparation method of Jinguanyin tea essence and application thereof in preparation of anti-tumor medicines. The preparation method comprises the following steps of (1) extracting the Jinguanyin tea leaves by hot water for two times at the temperature of 80 to 100 DEG C, wherein the adding amount of water for the first time of extracting is 5 to 30 times by volume, and the adding amount of water for the second time of extracting is 5 to 20 times by volume; screening the double extracted solutions, and combining the double filtrates, so as to obtain a Jinguanyin tea extracting solution; (2) concentrating the Jinguanyin tea extracting solution obtained in step (1), and drying, so as to obtain the Jinguanyin tea extract; (3) adding auxiliary materials into the Jinguanyin tea extract obtained in step (2), so as to obtain the Jinguanyin tea essence. The preparation method has the advantages that the green and environment-friendly effects are realized; the propertyis stable, and any obvious toxic or side effect is avoided; the Jinguanyin tea essence can be applied to preparation of foods, beverages, health-care foods, medicines or cosmetics with functions of clearing away ABTS (2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid)diammonium salt) and DPPH (2,2-diphenyl-1-picrylhydrazyl) free radicals, enhancing immunity of a human body, preventing breast cancer and colon cancer and assisting therapy.

Description

technical field [0001] The invention belongs to the technical field of medicine and food, and in particular relates to a preparation method of Jinguanyin tea essence and its application in the preparation of antitumor drugs. Background technique [0002] Jinguanyin tea (C.sinensis cv.Jin Guanyin), also known as Mingke No. 1, is a new fine variety of clones obtained from 1978 to 1999 with Tieguanyin as the female parent and Huang Jingui as the male parent by cross breeding. It belongs to the oolong tea family in Wuyi Mountain, Fujian Province or the oolong tea area with similar natural environment. It has been proved by scientific research that Tieguanyin contains high levels of amino acids, vitamins, minerals, tea polyphenols and alkaloids, and has a variety of nutritional and medicinal ingredients. , eliminate blood fat, lower cholesterol, reduce cardiovascular disease and diabetes and other effects. In addition, Jinguanyin tea is rich in tea polyphenols, and the caffeine...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/82A61P35/00A61K8/9789A61Q19/00A23F3/18A23F3/22A23F3/28A23F3/30A23L33/105
CPCA23F3/18A23F3/22A23F3/28A23F3/30A23L33/105A23V2002/00A61K8/97A61K36/82A61K2236/331A61K2236/39A61K2236/51A61K2800/10A61Q19/00A23V2200/308A23V2200/324A23V2200/30A23V2250/214A23V2250/6418A23V2250/642A23V2300/10A23V2300/14A23V2300/50
Inventor 陈填烽张晓斌代成俐尤媛媛
Owner JINAN UNIVERSITY
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