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Traditional Chinese medicine decoction for treating narcolepsy

A technology of narcolepsy and traditional Chinese medicine decoction, applied in the field of traditional Chinese medicine decoction, can solve problems such as unreasonable prescription compatibility, enhanced drug toxicity, and weakened therapeutic effect, so as to improve human immune function, reduce lethargy, and prevent disease recurrence Effect

Inactive Publication Date: 2018-03-09
秦月霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Common Chinese medicine prescriptions are difficult to take care of comprehensively with only a few herbs, and a variety of drugs must be properly combined to improve efficacy or reduce adverse reactions, so as to adapt to the treatment of complex diseases
In view of the complex interaction of various active ingredients of various Chinese medicinal materials in the body, changes in the pharmacokinetics and pharmacodynamics of various drugs in the body will have various effects on the interaction between drugs. When used in combination, it may not only produce synergistic drug effects, but also may produce antagonistic effects, which will lead to weakening of drug therapeutic effect or treatment failure. Some drugs in combination will also increase drug toxicity and cause adverse reactions; Enhanced, but when the therapeutic effect is excessively enhanced, it will exceed the body's ability to tolerate it, and it can also cause adverse reactions and even endanger patients.
Part of the research is to formulate traditional Chinese medicine prescriptions in order to treat narcolepsy. The most common problem is that the compatibility of the prescriptions is unreasonable, and it is often only based on the individual functions and indications of some single or compound medicines and certain pharmacodynamic indicators. According to the theory of traditional Chinese medicine, the taste of prescriptions can be added or subtracted at will, resulting in unreasonable prescriptions, which contradicts the theory of traditional Chinese medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Weighing: 9 grams of peony seed oil, 5 grams of iron knife wood leaves, 6 grams of lampstand leaves, 7 grams of different leaves Patoniae, 8 grams of wild persimmons, 14 grams of acacia skin, 13 grams of green fruits, 12 grams of turmeric, Shichangpu 10 grams, 11 grams of tangerine peel, 7 grams of Ma Lianan, 6 grams of Licorice moss, 5 grams of sugar palm, 4 grams of turmeric, 5 grams of mint, 6 grams of Atractylodes macrocephala, 8 grams of Dendrobium, pistachio 7 grams, 4 grams of chrysanthemum, 5 grams of Cimicifuga, 6 grams of Bupleurum, and 7 grams of wild cumin.

[0033] The preparation method is as follows: crush the above-mentioned medicinal materials except peony seed oil into coarse powder; decoct twice, add 8 times the amount of water for the first decoction, soak for 2 hours, decoct for 3 hours, filter; add water for the second decoction 6 times the amount, decoct for 2 hours, filter; combine the two decoctions and mix with peony seed oil evenly before pack...

Embodiment 2

[0051] Weighing: 6 grams of Dengtai leaves, 6 grams of different leaves Patoniae, 5 grams of wild persimmon, 10 grams of Ma Lianan, 6 grams of tooth leaf hanging stone lettuce, 8 grams of sugar palm, 4 grams of turmeric, 4 grams of mint, Atractylodes macrocephala 6 grams, 8 grams of Dendrobium, 6 grams of pistachio, 4 grams of chrysanthemum, 4 grams of Cimicifuga, 5 grams of Bupleurum, and 10 grams of wild cumin. The preparation method is the same as in Example 1.

[0052] Among the 10 narcolepsy patients selected from the Chinese medicine decoction made in Example 2 of the present invention, 8 cases were cured and 2 cases were markedly effective. The cure rate is 80%, and the total effective rate is 100%. The cured patients were followed up for 24 months, and no case of recurrence was found.

Embodiment 3

[0054] Weighing: 6 grams of Dengtai leaves, 6 grams of different leaves Patoniae, 5 grams of wild persimmon, 10 grams of Ma Lianan, 6 grams of tooth leaf hanging stone lettuce, 8 grams of sugar palm, 4 grams of turmeric, 4 grams of mint, Atractylodes macrocephala 6 grams, 8 grams of Dendrobium, 6 grams of pistachio, 4 grams of chrysanthemum, 4 grams of Cimicifuga, 5 grams of Bupleurum, and 10 grams of wild cumin. The preparation method is the same as in Example 1.

[0055] Among the 12 narcolepsy patients who selected the traditional Chinese medicine decoction made in Example 3 of the present invention, 11 cases were cured and 1 case was markedly effective. The cure rate is 91.6%, and the total effective rate is 100%. The improved and basically cured patients were followed up for 24 months, and no case of recurrence was found.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine decoction for treating narcolepsy, which is prepared from the following Chinese medicinal materials in the following weight proportions: 9 parts of peony seed oil, 5 parts of iron sword tree leaves, 6 parts of Dengtai leaves, different leaves 7 parts of papaya, 8 parts of wild persimmon, 14 parts of acacia skin, 13 parts of green fruit, 12 parts of turmeric, 10 parts of calamus, 11 parts of tangerine peel, 7 parts of horse stalk, 6 parts of dentate leaf hanging stone lettuce, sugar 5 parts brown, 4 parts turmeric, 5 parts mint, 6 parts Atractylodes macrocephala, 8 parts Dendrobium, 7 parts pistachio, 4 parts chrysanthemum, 5 parts cohosh, 6 parts Bupleurum, 7 parts wild cumin. Clinical experiments prove that the present invention helps to treat narcolepsy through the reasonable compatibility of Chinese medicinal materials, effectively reduces complications and prevents recurrence, and achieves good effects of overall regulation and long-term effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine decoction, in particular to a traditional Chinese medicine decoction for treating narcolepsy. Background technique [0002] Narcolepsy is a syndrome of unclear etiology characterized by abnormal sleep tendencies, including excessive daytime sleepiness, nocturnal restless sleep, and pathological REM sleep. This unexplained sleep disorder is characterized by prolonged periods of decreased vigilance and episodic episodes of irresistible sleep. Common Chinese medicine prescriptions are difficult to take care of comprehensively with only a few medicines, and a variety of medicines must be properly combined to improve the efficacy or reduce adverse reactions, so as to adapt to the treatment of complex diseases. In view of the complex interaction of various active ingredients of various Chinese medicinal materials in the body, changes in the pharmacokinetics and pharmacodynamics of various drugs in the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P25/20
CPCA61K36/71A61K9/0095A61K36/185A61K36/22A61K36/23A61K36/233A61K36/24A61K36/27A61K36/284A61K36/287A61K36/44A61K36/48A61K36/482A61K36/534A61K36/65A61K36/752A61K36/84A61K36/888A61K36/889A61K36/8984A61K36/9066A61K2236/331A61K2236/39A61K2300/00
Inventor 秦月霞其他发明人请求不公开姓名
Owner 秦月霞
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