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Chinese herbal medicine oral liquid for treating pediatric cold-evil stomachache, and preparation method thereof

A technology of Chinese herbal medicine and oral liquid, which is applied to pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc., can solve the problems of poor taste, large dose, inconvenience, etc., and achieve high compliance. , The effect of high product purity and convenient operation

Inactive Publication Date: 2018-03-06
福州博中技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, although the existing ginger and fennel compound product has the effect of relieving and treating abdominal pain due to cold pathogens, it fails to regulate the spleen and stomach at the same time due to the child's immature yang is not filled, the qi and blood are not filled, and the spleen and stomach are weak. the goal of
[0005] Most of the existing Chinese herbal medicine products for the treatment of cold-evil abdominal pain in children have a strong flavor of Chinese medicine, or their dosage forms are inconvenient for children to take, or the taste is poor, and children refuse to take them, or they need to be decocted by themselves. Effect
Such as Huoxiangzhengqi water (pill), Baohe Pill and patent CN104258337A disclose a kind of traditional Chinese medicine formula for deficiency cold abdominal pain, patent CN106309674A discloses a kind of pill for treating abdominal distention and abdominal pain, patent CN1147390A discloses Pediatric Belly Tongling, CN1915412A Disclosed is a decoction drug for treating abdominal pain-type diarrhea in children and its preparation method. These therapeutic drugs mostly use traditional Chinese medicines with the effect of warming the middle and dispelling cold. It is inconvenient to cook, the dosage is large and the taste is poor, which is not conducive to children's taking, and the pills are not conducive to children's swallowing, and children's taking compliance is poor
There are also some external patches in addition, such as patent CN 105169329 A disclosed infantile abdominal pain umbilical patch and preparation method thereof, patent CN105944071 A disclosed a kind of abdominal distension, abdominal pain navel patch, although these patches are easy to use, they can only be used in It works locally and cannot achieve the effect of treating both symptoms and root causes

Method used

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  • Chinese herbal medicine oral liquid for treating pediatric cold-evil stomachache, and preparation method thereof

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preparation example Construction

[0031] The present invention also provides a preparation method of the above-mentioned Chinese herbal medicine oral liquid for treating cold-evil abdominal pain in children, comprising the following steps:

[0032] Step 1. Grinding ginger and cumin respectively, and performing supercritical carbon dioxide extraction respectively to obtain ginger extract and cumin extract. The process conditions of the supercritical carbon dioxide extraction are: extraction pressure 25-30 MPa, extraction temperature 40 ~60℃, extraction time 150~200min and carbon dioxide flow rate 380~390kg / h;

[0033] Step 2. Soak the licorice in water for 30-60 minutes, decoct 3 times, combine the decoction liquid, filter, and concentrate to obtain licorice juice; soak the jujube in water for 30-60 min, decoct 3 times, combine the decoction liquid, and filter , concentrated to make jujube juice;

[0034] Step 3. Mix the ginger extract and fennel extract obtained in step 1, the licorice juice and jujube juice ...

Embodiment 1

[0042] A Chinese herbal medicine oral liquid for treating cold-evil abdominal pain in children, comprising the following raw materials: 6g of ginger extract, 6g of cumin extract, 5g of licorice juice, 8g of jujube juice, and 5g of honey.

[0043] The present invention also provides a preparation method of the above-mentioned Chinese herbal medicine oral liquid for treating cold-evil abdominal pain in children, comprising the following steps:

[0044] Step 1, (1) Weigh 1kg of ginger and 1kg of fennel, wash them, remove the moldy parts, slice the ginger, put the ginger and cumin in a far-infrared drying oven at 50°C for 72 hours, and stir them in the middle to make dry evenly;

[0045] (2) The pulverizer pulverizes the dried ginger and fennel, passes through a 60-mesh sieve to obtain ginger powder and cumin powder, and conducts supercritical carbon dioxide extraction respectively, and sets the extraction conditions: extraction pressure 25MPa, extraction temperature 40°C, extract...

Embodiment 2

[0055] A Chinese herbal medicine oral liquid for treating cold-evil abdominal pain in children, comprising the following raw materials: 8 g of ginger extract, 8 g of cumin extract, 7 g of licorice juice, 10 g of jujube juice, and 10 g of honey.

[0056] The present invention also provides a preparation method of the above-mentioned Chinese herbal medicine oral liquid for treating cold-evil abdominal pain in children, comprising the following steps:

[0057] Step 1, (1) Wash 1.2kg of ginger and 1.2kg of cumin, remove the rotten parts, slice the ginger, dry the ginger and cumin in a far-infrared drying oven at 50°C for 72 hours, and stir in the middle. make it dry evenly;

[0058] (2) The pulverizer pulverized the dried ginger and cumin, passed through a 60-mesh sieve to obtain ginger powder and cumin powder, and carried out supercritical carbon dioxide extraction respectively, and set the extraction conditions: extraction pressure 28MPa, extraction temperature 55°C, extraction ...

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Abstract

The invention relates to the field of traditional Chinese medicines, particularly relates to a Chinese herbal medicine oral liquid for treating pediatric cold-evil stomachache, and a preparation method thereof. The Chinese herbal medicine oral liquid comprises the following raw materials in parts by weight: 6-15 parts of ginger extract, 6-15 parts of sweet fennel extract, 5-15 parts of liquorice juice, 8-20 parts of Chinese date juice and 5-20 parts of honey. The ginger extract and sweet fennel extract are prepared by adopting a supercritical carbon dioxide extraction method, and the liquoricejuice and Chinese date juice are prepared by adopting a decocting method. The Chinese herbal medicine oral liquid is prepared by combining the supercritical carbon dioxide extraction method with thetraditional Chinese medicine technology, can effectively regulate the spleen and the stomach while relieving or eliminating the pediatric cold-evil stomachache, and can achieve the purposes of treating both symptoms and root causes, and facilitating administration.

Description

technical field [0001] The invention relates to a medicine for treating cold-evil abdominal pain in children, in particular to a Chinese herbal medicine oral liquid for treating cold-evil abdominal pain in children and a preparation method thereof. Background technique [0002] Pain below the epigastric cavity, around the navel, and above the pubic bone is collectively referred to as abdominal pain. The onset of abdominal pain in internal medicine is slow and persistent. Children often show unexplained paroxysmal or persistent crying, bending of lower limbs to the abdomen, protecting the abdomen with hands, clenching fists, restless, pale complexion, sweating and refusal to eat And listlessness, etc.; after abdominal pain occurs in children, it is often accompanied by systemic reactions such as nausea, vomiting, constipation, diarrhea, abdominal distension, high fever, and loss of appetite. [0003] Traditional Chinese medicine believes that abdominal pain in children is of...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/08A61P1/00A61P29/00A61K35/644
CPCA61K9/0095A61K35/644A61K36/235A61K36/484A61K36/725A61K36/9068A61K47/12A61K47/36A61K2236/331A61K2236/37A61K2236/39A61K2300/00
Inventor 林健勇张会会叶燕军张娜蔡燕峰
Owner 福州博中技术开发有限公司
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