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Traditional Chinese medicine composition gel for relieving gynecologic inflammation and contracting vagina and preparation technology thereof

A technology of gynecological inflammation and production technology, which is applied in the direction of drug combination, drug delivery, active ingredients of hydroxyl compounds, etc., can solve the problems of destroying the vaginal physiological environment, vaginal flora imbalance, and large irritation, so as to achieve convenient use and restore vaginal elasticity , Improve the effect of smell

Inactive Publication Date: 2018-02-06
方晓东
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many disinfectant preparations in China for the solution of such problems, such as chlorhexidine acetate, benzalkonium chloride and other preparations for bacterial infections, and dacryline suppository for fungi, etc., while eliminating various pathogenic bacteria, they are also effective for vaginal infection. The internal environment has a certain impact, resulting in a decline in the vaginal self-cleaning system
It is clinically characterized by drug resistance, high irritation, and allergies; in addition, these drugs are often prone to adverse reactions and complications, causing vaginal flora imbalance, destroying the normal physiological environment of the vagina, and aggravating inflammation.

Method used

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  • Traditional Chinese medicine composition gel for relieving gynecologic inflammation and contracting vagina and preparation technology thereof
  • Traditional Chinese medicine composition gel for relieving gynecologic inflammation and contracting vagina and preparation technology thereof
  • Traditional Chinese medicine composition gel for relieving gynecologic inflammation and contracting vagina and preparation technology thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] All the Chinese medicinal materials used in the present invention are used after cleaning and removing impurities, which is the common knowledge of those skilled in the art, and Fructus Cnidii among the present invention, Dipsacus, Cortex Phellodendri, Aloe, pearl powder, and saffron are all purchased in Guangzhou Dashenlin Pharmaceutical Co., Ltd., no longer discuss in the present embodiment and other embodiments, get Fructus Cnidii 220g, Dipsacus 180g, Cortex Phellodendri 175g, Aloe 90g, pearl powder 85g, Saffron 4.2g are mixed and pulverized, add 5300g of Purified water, decoct for 1.5 hours, and filter to obtain the filtrate and filter residue, add 3700g of purified water to the filter residue and decoct for 1 hour again, after filtering, mix the obtained filtrate with the filtrate in the previous step, at a temperature of 55 ° C Concentrate by evaporation to a measured density of 1.1g / cm 3 , to obtain 380ml of mixed solution, add 1140ml of ethanol, stir and mix wel...

Embodiment 2

[0040] Get 270g of Cnidium Fructus, 220g of Dipsacus, 220g of Cortex Phellodendri, 110g of Aloe, 110g of pearl powder, and 5.6g of saffron, mix and pulverize, add 8000g of purified water, decoct for 1.5 hours, and filter to obtain filtrate and filter residue, add 5600g of purified Decoct the water again for 1 hour, filter and mix the obtained filtrate with the filtrate in the previous step, evaporate and concentrate at a temperature of 65°C to a measured density of 1.16g / cm 3, to obtain 460ml of mixed solution, add 1380ml of ethanol, stir and mix well, and let it stand for 24 hours, take 1680ml of supernatant and transfer it to a container, heat and distill to remove ethanol, until there is no ethanol smell in the volatilized gas, stop to obtain immersion The paste is about 243g, wherein the dry powder quality after the drying of the extract is 85.8% of the mass of the extract, and 65g of the extract is taken for subsequent use.

[0041] Preparation of composition A: Take 3g o...

Embodiment 3

[0048] Take 250g of Fructus Cnidii, 200g of Dipsacus, 200g of Phellodendron cortex, 100g of aloe, 100g of pearl powder, and 5g of saffron, mix and pulverize, add 6800g of purified water, decoct for 1.5 hours, and filter to obtain the filtrate and filter residue, add 4700g of purified water to the filter residue Decoct again for 1 hour, filter and mix the obtained filtrate with the filtrate in the previous step, evaporate and concentrate at a temperature of 60°C until the measured density is 1.20g / cm 3 , to obtain 450ml of mixed solution, add 1350ml of ethanol, stir and mix well, and let it stand for 24 hours, take 1650ml of supernatant and transfer it to a container, heat and distill to remove ethanol, until there is no ethanol smell in the volatilized gas, stop to obtain immersion The paste is about 233g, wherein the dry powder quality after drying of the extract is 89.6% of the extract mass, and 65g of the extract is taken for subsequent use.

[0049] Preparation of composit...

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Abstract

The invention discloses a traditional Chinese medicine composition gel for relieving gynecologic inflammation and contracting vagina and a preparation technology thereof, and belongs to the field of traditional Chinese medicine preparations. The traditional Chinese medicine composition gel is prepared from the following components of fructus cnidii, radix dipsaci, herba selaginellae, aloe, pearl powder, extract and matrine of crocus sativus, borneol, yeast, collagen, glycerin, nanosilver, carbomer, hyaluronic acid, rose essential oil, seabuckthorn seed oil and other auxiliary materials in a matching way; in the preparation process, triethanolamine is dripped; the ratio of the extract in the traditional Chinese medicine composition is about 6.5%. The traditional Chinese medicine compositiongel has the advantages that the effects of relieving gynecologic inflammation and restoring elasticity of vagina are stronger; the gel is prepared by the applicable technology, so that a user can conveniently carry and use; after proofing, the irritation to the vagina is avoided, and the stronger bacteria-inhibiting function is realized.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine composition gel for gynecological inflammation and Yin reduction and its production process. Background technique [0002] Women's gynecological problems are very common: due to women's special physiological structure and physiological characteristics, female gynecological inflammations such as vaginitis, cervicitis, pelvic inflammatory disease, and adnexitis have become one of the important factors affecting women's health. There are many muscles and ligaments around the vagina of normal women to maintain a certain tension. After sexual life, the vaginal opening expands, especially after married women have vaginal delivery. After sexual life, the vaginal opening expands, and the risk of various serious infections increases , Seriously affecting women's health and family harmony. Studies have shown that there is a certain correlation be...

Claims

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Application Information

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IPC IPC(8): A61K38/39A61K9/06A61K47/32A61K47/36A61K47/44A61K47/26A61P15/00A61P15/02A61P29/00A61K31/045A61K31/4375A61K31/785A61K33/38A61K35/618A61K36/896A61K36/886
CPCA61K36/234A61K9/0034A61K9/06A61K31/045A61K31/4375A61K31/785A61K33/38A61K35/618A61K36/185A61K36/756A61K36/88A61K36/886A61K36/896A61K38/39A61K47/26A61K47/32A61K47/36A61K47/44A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 方晓东
Owner 方晓东
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