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Perfusion agent for preventing and treating postpartum hypocalcemia and ketosis of dairy cows

A technology for hypocalcemia and ketosis, applied in the direction of metabolic diseases, active ingredients of aluminum/calcium/magnesium, drug combination, etc., can solve problems such as large losses, achieve the effects of preventing ketosis, improving blood levels, and reducing the elimination rate

Inactive Publication Date: 2018-01-09
上海健荷牧业科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] In fact, the incidence of subclinical hypocalcemia in production is much higher than that of clinical hypocalcemia (USDA National Animal Health Monitoring Survey, 1996, 2007, Reinhardt et al. 2011), so the losses caused by it may be much greater

Method used

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  • Perfusion agent for preventing and treating postpartum hypocalcemia and ketosis of dairy cows
  • Perfusion agent for preventing and treating postpartum hypocalcemia and ketosis of dairy cows
  • Perfusion agent for preventing and treating postpartum hypocalcemia and ketosis of dairy cows

Examples

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Embodiment 1

[0032] This embodiment provides a kind of gavage preparation for preventing and treating postpartum hypocalcemia and ketosis in dairy cows, which includes the following components in parts by mass: 85 parts of calcium chloride, 106 parts of coated slow-release calcium chloride, 250 parts of calcium chloride, 100 parts of rumen-passed choline chloride, 50 parts of magnesium sulfate, and 409 parts of maltodextrin.

[0033] How to use: Dissolve 1000g of gavage agent in 30kg of warm water at 38°C and feed cows immediately after giving birth.

[0034] The formula of the control group: 175 parts of calcium chloride, 250 parts of calcium propionate, 50 parts of magnesium sulfate, and 525 parts of maltodextrin.

[0035] In the experiment, 20 dairy cows with 2 parities 21 days before delivery were randomly divided into 2 groups according to the milk production. They were raised in a loose manner and had free access to drinking water. This test was used to evaluate the effect of the gav...

Embodiment 2

[0039] This embodiment provides a kind of gavage preparation for preventing and treating postpartum hypocalcemia and ketosis in dairy cows, which includes the following components in parts by mass: 85 parts of calcium chloride, 106 parts of coated slow-release calcium chloride, 250 parts of calcium chloride, 100 parts of rumen-passed choline chloride, 50 parts of magnesium sulfate, and 409 parts of maltodextrin.

[0040] The formula of the control group: 175 parts of calcium chloride, 250 parts of calcium propionate, 50 parts of magnesium sulfate, and 525 parts of maltodextrin.

[0041] In the experiment, 60 dairy cows with more than 2 litters 21 days before delivery were randomly divided into 2 groups according to the milk output of the last parity. The influence of clinical hypocalcemia, postpartum disease, elimination rate and production performance (Table 2, Table 3, Table 4). Results showed reduced incidence of ketosis and hypocalcemia, improved production performance, a...

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Abstract

The invention relates to a perfusion agent for preventing and treating postpartum hypocalcemia and ketosis of dairy cows. The perfusion agent is prepared from the following components in parts by mass: 400-500 parts of a calcium supplement from different sources, 100-200 parts of an energy metabolism regulator, 50-100 parts of a magnesium supplement and the balance of a carrier. The perfusion agent can effectively raise the blood level of the dairy cows and prevent or treat the hypocalcemia through postpartum perfusion; lipid mobilization of the dairy cows is relieved, blood beta-hydroxybutyric acid and free fatty acid are reduced, and the ketosis is prevented; abomasum displacement is prevented; the milk yield of the dairy cows is increased, the early lactation elimination rate is reduced, and good application prospect is achieved.

Description

technical field [0001] The invention belongs to the field of dairy cow premix, in particular to a gavage agent for preventing and treating postpartum hypocalcemia and ketosis in dairy cows. Background technique [0002] The transition period of dairy cows is defined as 3 weeks before calving to 3 weeks after calving (Grummer, 1995; Drackley, 1999), during which drastic changes occur in dairy cow endocrine, such as insulin, growth hormone, thyroxine, estrogen, etc. (Kunz et al., 1985, Chew et al. 1975, 1979). This drastic change in hormone secretion leads to a sharp drop in feed intake of dairy cows before / after delivery, and the recovery of feed intake is slow, while milk production rises rapidly, and the energy excreted by dairy cows through milk is much lower than the energy consumed, making Dairy cows are in a state of negative energy balance. In this case, dairy cows mobilize the fat stored in the body to meet the needs of lactation. The mobilization of fat will greatly...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/06A61P3/14A61P3/00
Inventor 边四辈肖玲
Owner 上海健荷牧业科技有限公司
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