Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of anti-adhesion moist dressing for promoting burn wound healing and preparation method thereof

A wet dressing and wound healing technology, applied in bandages, absorbent pads, medical science, etc., can solve problems such as wound adhesion, achieve the effects of avoiding infection, automatically adjusting swelling balance, and reducing inflammatory reactions

Active Publication Date: 2020-07-14
靖远县瑞淼商贸有限公司
View PDF4 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In view of the above-mentioned deficiencies in the prior art, the purpose of the present invention is to provide an anti-adhesion wet dressing for promoting burn wound healing and a preparation method thereof, so as to solve the problem that the existing dressing is easy to adhere to the wound

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of anti-adhesion moist dressing for promoting burn wound healing and preparation method thereof
  • A kind of anti-adhesion moist dressing for promoting burn wound healing and preparation method thereof
  • A kind of anti-adhesion moist dressing for promoting burn wound healing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] The preparation method of this embodiment comprises the following steps:

[0043] (1) sodium carboxymethyl cellulose is dissolved in propylene glycol deionized aqueous solution by mass volume percentage 2.0% (the quality of sodium carboxymethyl cellulose and the volume percentage of propylene glycol aqueous solution are 2.0%, other embodiments are also the same), Prepare sodium carboxymethyl cellulose / propylene glycol aqueous solution; wherein, in the propylene glycol deionized aqueous solution, the mass percentage concentration of propylene glycol and deionized water is 1.0%, the stirring speed is 500r / min during preparation, and the stirring time is 1.5h. Keep the solution temperature at 30 °C.

[0044] (2) Sodium alginate is dissolved in the sodium carboxymethyl cellulose / propylene glycol aqueous solution prepared in step (1) by mass volume percentage 2.0% (the quality of sodium alginate and the sodium carboxymethyl cellulose and propylene glycol mixed solution prepa...

Embodiment 2

[0048] The preparation method of this embodiment is as follows:

[0049] (1) Sodium carboxymethyl cellulose is dissolved in propylene glycol deionized aqueous solution by mass volume percentage 2.0%, is mixed with sodium carboxymethyl cellulose / propylene glycol aqueous solution; Wherein, in propylene glycol deionized aqueous solution, the quality of propylene glycol is the same as that of deionized water The volume percentage concentration is 1.0%, the stirring speed is 500r / min, the stirring time is 1.5h, and the solution temperature is kept at 30°C

[0050] (2) Sodium alginate is dissolved in the sodium carboxymethyl cellulose / propylene glycol aqueous solution prepared in step (1) according to the mass volume percentage of 3.0%, and is prepared into a sodium carboxymethyl cellulose / sodium alginate / propylene glycol colloidal solution; wherein, when preparing The stirring speed was 500r / min, the stirring time was 1.5h, and the temperature of the solution was kept at 30°C.

[...

Embodiment 3～10

[0054] The difference between Examples 3-10 and Example 1 is that the mass volume percentage of propylene glycol, sodium carboxymethyl cellulose, sodium alginate and chitosan are different by mass volume percentage when preparing the solution, as shown in Table 1. Other operations are the same.

[0055] The mass volume percentage concentration of four kinds of substances in the solution prepared by the embodiment 1~10 of table 1

[0056] Example Propylene Glycol / % Sodium carboxymethyl cellulose / % Sodium alginate / % Chitosan / % 1 1 2 2 1 2 1 2 3 1 3 1 2 3 2 4 1 2 4 3 5 1 3 2 2 6 1 3 3 3 7 1 3 4 1 8 1 4 2 3 9 1 4 3 1 10 1 4 4 2

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
massaaaaaaaaaa
pore sizeaaaaaaaaaa
Login to View More

Abstract

The invention discloses anti-sticking wet dressing for promoting the healing of a burn wound and a preparation method of the anti-sticking wet dressing. The wet dressing is prepared from a polypropylene non-woven fabric and compound hydrogel stuck on the polypropylene non-woven fabric, wherein the compound hydrogel can be used for self-adjusting a wet environment of the burn wound and is prepared from a colloidal solution of sodium carboxymethyl cellulose, sodium alginate, chitosan and propylene glycol. The wet dressing is prepared from four substances including the propylene glycol, the sodium carboxymethyl cellulose, the sodium alginate and the chitosan, wherein the sodium carboxymethyl cellulose and the sodium alginate are water-soluble high polymers and a mixed reaction system of the sodium carboxymethyl cellulose and the sodium alginate is used as a water-soluble matrix; when medicines are replaced, the water-soluble matrix can be dissolved by liquid; the chitosan is used as an anti-sticking component, is dissolved into the water-soluble matrix of the sodium carboxymethyl cellulose and the sodium alginate through high-strength mechanical stirring and plays a role in sticking resistance in a process of sticking the wet dressing on the wound.

Description

technical field [0001] The invention belongs to the field of wound dressing preparations, in particular to an anti-adhesion wet dressing for promoting burn wound healing and a preparation method thereof. Background technique [0002] In China, there are as many as 5 to 10 million burn victims every year, and about 5% of them require hospitalization. Although they benefit from medical support and post-injury care, large sample statistics show that the mortality rate of burn patients in my country is still high. Maintained at 2.25-5.41%. Various damages caused by burns, such as non-healing wounds and pressure ulcers, are all related to the destruction and loss of the skin barrier function, such as: increased metabolism, decreased body temperature, excessive loss of water, massive loss of protein, and impairment of the endocrine and immune systems. Disorder etc. Patients with severe burns will not only cause certain damage to the patient's skin and deep tissues, but also have ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/28A61L15/20
CPCA61L15/20A61L15/28C08L1/286C08L5/04C08L5/08
Inventor 陈忠敏梁敏王富平刘澜童晓波
Owner 靖远县瑞淼商贸有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com