Method for extracting rutin from ilex latifolia thunb

Abstract

The invention relates to a method for extracting rutin from ilex latifolia thumb. The method comprises technical steps: performing continuous reflux treatment to dried pulverized ilex latifolia thumb with acetone in a water-bath at 50-60 DEG C for 2-4 h, recycling acetone, airing a sample, taking 70-80% of ethanol as an extraction medium with the weight volume ratio of material to liquid being 1:(20-30), performing ultrasonic extraction and filtering, carrying out pressure reduction to recycle ethanol, continuously performing ultrasonic treatment to mother liquor for 1 h, performing cooling and standing for crystallization, performing pumping filtration to obtain a crude rutin product, performing continuous reflux treatment to the crude rutin product with acetone for 0.5-1 h, recycling acetone, drying the sample, adding distilled water at a weight volume ratio of 1:100 for heating and dissolving the sample, performing filtering while the obtained product is hot, and performing cooling and standing for crystallization to obtain a fine rutin product. Through adoption of ultrasonic-assisted extraction technology, the extraction efficiency and yield are improved. The method is simple in operation process, allows ilex latifolia thumb resources which are abundant in the southwest region of China to be fully used, develops a new field of ilex latifolia thumb application, and solves the problem that a rutin raw material is tight.

Description

technical field [0001] The invention belongs to the field of medicine and relates to a method for extracting and refining rutin from Kudingcha. Background technique [0002] Rutin (Rutin), which belongs to flavonoids, is also known as rutin, vitamin P, and purple quercetin; it not only reduces the permeability and fragility of capillaries, but also maintains and restores the normal elasticity of capillaries. It is used to prevent and treat hypertensive cerebral hemorrhage, diabetic retinal hemorrhage and hemorrhagic purpura. [0003] At present, the methods for producing rutin mainly include: 1. hot water extraction method, although this method is simple in process and low in equipment requirements, but the product yield is low and the quality is poor; 2, alkali extraction-acid precipitation method, this method prepares rutin Although the product quality is slightly better, the yield is on the low side; 3, solvent extraction method, although this method yield is guaranteed,...

AI Technical Summary

Problems solved by technology

[0003] At present, the methods for producing rutin mainly include: 1, hot water extraction method, although this method is simple in process and low in equipment requirements, but the product yield is low and the quality is poor; 2, alkali extraction-acid precipitation method, this method prepares Although the quality of the product is slightly better, the yield is low; 3. Solvent extraction method, although the yield of this method is guaranteed, the refining of the product is quite difficult, and the product content is low

It can be seen that the above methods have their own advantages and disadvantages.