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Anti-allergic plant composition and application thereof

A composition and anti-allergic technology, which is applied in the direction of drug combination, plant raw materials, allergic diseases, etc., to achieve high safety, stable quality, and remarkable anti-allergic effect

Active Publication Date: 2017-08-18
NORTHEAST AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there is no report about the research on the anti-allergic skin care products of D.

Method used

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  • Anti-allergic plant composition and application thereof
  • Anti-allergic plant composition and application thereof
  • Anti-allergic plant composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Example 1: Optimization of the Extraction Process for the Active Components of D.

[0060] 1. The effect of solid-liquid ratio on the inhibition rate of hyaluronidase activity

[0061] Take by weighing 5 parts of 20.0g dry hair fern powder, respectively according to the solid-liquid ratio of 1:5g / mL, 1:10g / mL, 1:15g / mL, 1:20g / mL, 1:25g / mL Proportional addition of ethanol solution with a volume fraction of 70% (v / v), ultrasonic extraction at a temperature of 30°C for 30 minutes respectively, and the extraction solution was concentrated into an extract after suction filtration. The extract was dissolved into 1% alcohol solution respectively, and then the hyaluronidase inhibition test was carried out to investigate the effect of the ratio of solid to liquid on the inhibition rate of hyaluronidase activity. The results are shown in figure 1 . Depend on figure 1 It can be seen that with the increase of the ratio of solid to liquid, the inhibition of the activity of Tricho...

Embodiment 2

[0079] Example 2: Research on anti-allergy efficacy of 4 kinds of Chinese herbal medicine extracts

[0080] Take 0.1mL 0.25mmol / L CaCl 2 solution and 0.5mL hyaluronidase solution, kept at 37°C for 20 minutes in a water bath; adding sample solutions (respectively, extracts of Trichomonas edulis, extracts of Scutellaria baicalensis, cactus extracts and licorice extracts, all in alcohol solutions with a concentration of 1.0%, The volume fraction of ethanol is 5%) 0.5mL, 37°C water bath for 20min; add sodium hyaluronate solution 0.5mL, 37°C water bath for 30min, and place at room temperature for 5min; add 0.4mol / L NaOH solution 0.1mL, add acetylacetone solution 0.5mL, heated in boiling water bath for 15min, then immediately cooled with ice water for 5min; add 1.0mL Ehrlich reagent, 3.0mL absolute ethanol, develop color for 20min, use deionized water as a control, measure its absorbance at 539nm value.

[0081] Hyaluronidase inhibition rate (%)=[(A-B)-(C-D)] / (A-B)×100%

[0082] ...

Embodiment 3

[0087] Embodiment 3: the research of 4 kinds of Chinese herbal medicine extracts inhibiting skin bacteria

[0088] 1) Activation of strains: pick the bacteria with an inoculation ring and streak on the plate, put them into an incubator for upside-down culture (culture at 37°C for 24 hours for bacteria; 48 hours for fungi at 28°C). After the colonies grow, pick a single colony Re-activation by streaking on the plate again. In principle, activation by streaking on the plate three times can achieve the activation of the strain. Take the activated strain, and under sterile conditions, pick a colony with an inoculation loop and add it to the liquid medium , placed in a shaker, bacteria were cultured for 12h-14h at a temperature of 37°C, fungi were cultured for 3d-5d at a temperature of 28°C.

[0089] 2) Preparation of bacterial suspension: Dilute the cultivated bacterial liquid with liquid medium by 10-fold dilution method to make a series of bacterial suspensions, use a hemocytome...

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Abstract

The invention discloses an anti-allergic plant composition and application thereof and belongs to the technical field of cosmetics. The composition comprises Dryopteris fragrans extract, radix scutellariae extract, opuntia extract and radix glycyrrhizae extract. The anti-allergic plant composition has the advantages that the raw materials used by the composition are mild natural components and contain rich substances such as amino acid and trace elements capable satisfying human body physiological needs and anti-allergic substances; the anti-allergic plant composition can be prepared into three skincare products which include a facial cleanser, a toner and a moisturizing lotion according to the needs and convenience of users, and the users can select and use the skincare products according to the needs.

Description

technical field [0001] The invention relates to an antiallergic plant composition and its application, belonging to the technical field of cosmetics. Background technique [0002] In recent years, with the aggravation of environmental pollution, the abuse of various industrial additives, and changes in people's eating habits, the number of allergic patients has increased sharply and the symptoms have become more serious. According to incomplete statistics, there are more and more people around the world who feel sensitive skin, of which 61% are women and 38% are men. Skin allergies have become one of the important problems that plague human health. Skin allergic reaction, also known as allergic reaction or hypersensitivity reaction, refers to a special type of immune response produced by the body when it is stimulated by an antigen, which can cause tissue damage and immune function disorder. Appearing on people is also called allergic contact dermatitis, which is characteri...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/9749A61Q19/00A61Q17/00A61Q19/10A61K36/539A61P37/08
CPCA61K8/97A61K36/12A61K36/33A61K36/484A61K36/539A61K2236/333A61K2236/39A61K2236/51A61K2800/5922A61K2800/72A61Q17/005A61Q19/00A61Q19/10A61K2300/00
Inventor 常缨王会兰贾雯靖张冬瑞韩佳良
Owner NORTHEAST AGRICULTURAL UNIVERSITY
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