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Silicone gel capable of removing scar and preparation method of silicone gel

A technology of silicone gel and scar removal, which is applied in the direction of medical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., which can solve problems such as unsatisfactory and difficult absorption, and ensure hydration Tenders, smoothes and softens scars with manageable results

Active Publication Date: 2017-07-28
HENAN HUIBO MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing silicone gel products are relatively greasy and are not easily absorbed after application. They are often unsatisfactory in terms of scar pigmentation, improvement of scar itching, erythema, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A scar-removing silicone gel prepared from the following parts by weight of raw materials: 5 parts of dimethyl silicone oil, 10 parts of hexamethyldisiloxane, and 60 parts of polydimethylsiloxane self-crosslinking polymer Parts, 2 parts of Moutan bark extract, 3 parts of Aloe-Emodin, 2 parts of Matrine, 3 parts of Calamine; Among them, Mouton Bark extract, Aloe-Emodin and Matrine are all oily extracts; Polydimethyl The molecular weight of the siloxane self-crosslinking polymer is 8000; the viscosity of hexamethyldisiloxane is 15 cst.

[0020] The preparation method of the above-mentioned scar-removing silicone gel includes taking dimethicone, hexamethyldisiloxane, and polydimethylsiloxane self-crosslinking polymer in parts by weight, and then adding the Moutan bark extract , Aloe-emodin, matrine and calamine, stir evenly, and fill it in a medical aluminum-plastic packaging tube to complete.

Embodiment 2

[0022] A scar-removing silicone gel prepared from the following parts by weight of raw materials: 1 part of dimethyl silicone oil, 30 parts of hexamethyldisiloxane, and 20 parts of polydimethylsiloxane self-crosslinking polymer Parts, 2 parts of Moutan bark extract, 4 parts of Aloe-Emodin, 3 parts of Matrine, 5 parts of Calamine; Among them, Moutan Bark Extract, Aloe-Emodin and Matrine are all oily extracts; Polydimethyl The molecular weight of the siloxane self-crosslinking polymer is 10,000; the viscosity of hexamethyldisiloxane is 50 cst.

[0023] The preparation method of the above-mentioned scar-removing silicone gel includes taking dimethicone, hexamethyldisiloxane, and polydimethylsiloxane self-crosslinking polymer in parts by weight, and then adding the Moutan bark extract , Aloe-emodin, matrine and calamine, stir evenly, and fill it in a medical aluminum-plastic packaging tube to complete.

Embodiment 3

[0025] A scar-removing silicone gel prepared from the following parts by weight of raw materials: 10 parts of dimethyl silicone oil, 15 parts of hexamethyldisiloxane, and 45 parts of polydimethylsiloxane self-crosslinking polymer Parts, 5 parts of Moutan bark extract, 3 parts of aloe-emodin, 2 parts of matrine, and 2 parts of calamine; among them, Moutan bark extract, aloe-emodin and matrine are all oily extracts; polydimethyl The molecular weight of the siloxane self-crosslinking polymer is 20,000; the viscosity of hexamethyldisiloxane is 10 cst.

[0026] The preparation method of the above scar-removing silicone gel includes taking dimethicone, hexamethyldisiloxane, and polydimethylsiloxane self-crosslinking polymer in parts by weight, and then adding the Moutan cortex extract , Aloe-emodin, matrine and calamine, stir evenly, and fill it in a plastic tube to complete.

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Abstract

The invention relates to the technical field of biological medicines and particularly relates to a silicone gel capable of removing a scar and a preparation method of the silicone gel. The silicone gel is prepared from the following raw materials in parts by weight: 1-10 parts of dimethyl silicone oil, 10-30 parts of hexamethyldisiloxane, 20-60 parts of a polydimethylsiloxane self-crosslinking polymer, 0-10 parts of a natural plant antimicrobial agent and 0-5 parts of an antipruritic agent. The dimethyl silicone oil and the polydimethylsiloxane self-crosslinking polymer can be quickly crosslinked and combined with other components under the action of the hexamethyldisiloxane and the hexamethyldisiloxane has high volatility, is capable of quickly promoting various substances to form a thin film after being crosslinked and combined, and is well tightly laminated with epidermis; hydration of skin is ensured; the silicone gel has the effects of smoothing and softening scars caused by various external causes; and meanwhile, various components work together, so that scar hyperpigmentation is significantly improved and the symptoms such as pruritus and erythema are improved.

Description

Technical field [0001] The invention relates to the technical field of biomedicine, in particular to a scar-removing silicone gel and a preparation method thereof. Background technique [0002] Scar is repaired by connective tissue instead of histological regeneration after injury. It is a kind of compensatory incomplete regeneration, and its essence is an abnormal and unsound tissue without normal skin structure and function. . Burns, scalds, and surgical operations are the main causes of hypertrophic scars in skin tissues. At the same time, factors such as imbalance of collagen metabolism, contraction of myofibroblasts, and changes in dermal extracellular matrix components can also produce hypertrophic scars. [0003] Silicone gel is the first-line product recommended by global medical experts to treat scars and can create an ideal environment for scars. In addition, silicone gel has the characteristics of low permeability to water molecules, which can play the same role as the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K36/65A61K9/06A61P17/02A61K31/122A61K31/4375A61K33/30
CPCA61K9/0014A61K9/06A61K31/122A61K31/4375A61K33/30A61K36/65A61K36/71A61K47/34A61K2300/00
Inventor 张艳琦周新钦刘尧高勇
Owner HENAN HUIBO MEDICAL CO LTD
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