A traditional Chinese medicine preparation for treating rheumatoid arthritis and rheumatic pain, its preparation method and application

A technology for rheumatoid arthritis and traditional Chinese medicine preparations, applied in the field of traditional Chinese medicine preparations, can solve problems such as poor clinical compliance and inability to change the course of disease, and achieve the effects of low production cost, significant curative effect, and high safety margin

Active Publication Date: 2021-01-01
CHENGDU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Commonly used drugs include glucosamine hydrochloride granules, ibuprofen, penicillamine, diclofenac, aspirin, indomethacin, etc., which produce anti-inflammatory and analgesic effects by inhibiting the synthesis of prostaglandins and relieve pain, but cannot change the course of the disease. The course of the disease, and the side effects (gastrointestinal bleeding, myocardial infarction, thrombus, etc.) are very obvious, and the clinical compliance is poor

Method used

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  • A traditional Chinese medicine preparation for treating rheumatoid arthritis and rheumatic pain, its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] Embodiment 1: Granules

[0081] Raw material formula: Yanhusuo 300g, Qingfengteng 450g, Pittosporum bark 450g, sliced ​​turmeric 300g

[0082] Preparation method: take Yanhusuo, Qingfengteng, Pittogonia bark, and turmeric slices, put them into 60% ethanol whose weight is 8 times the total weight of Corydalis chrysanthemum, Qingfengteng, Pittogonia bark, and sliced ​​turmeric, and reflux extraction for 3 times, Each time for 2 hours, after each reflux extraction, filter, combine the filtrate and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.20-1.30, then add dextrin, dry, grind, add starch slurry, and granulate.

[0083] Functions and indications: heat-clearing and toxic substances removing, anti-inflammatory and analgesic. It is used for the treatment of fever, redness, swelling, inflammation and pain caused by rheumatoid arthritis and rheumatism.

[0084] Usage and dosage: take orally, 2-3 times a day, 10-20g each time.

Embodiment 2

[0085] Embodiment 2: capsules

[0086] Raw material formula: Corydalis Corydalis 450g, Qingfengteng 300g, Pittodia bark 300g, sliced ​​turmeric 450g

[0087] Preparation method: take Yanhusuo, Qingfengteng, Pittogonia bark, and turmeric slices, put them into 90% ethanol whose weight is 6 times the total weight of Corydalis chrysanthemum, Qingfengteng, Pittogonia peel, and turmeric slices, and reflux for extraction twice, 2 hours each time, after each reflux, filter, combine the filtrate and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.15-1.20, then add starch or dextrin, dry, crush, sieve and pack into capsules.

[0088] Functions and indications: heat-clearing and toxic substances removing, anti-inflammatory and analgesic. It is used to treat inflammation and pain caused by rheumatoid arthritis and rheumatic pain.

[0089] Dosage: Take orally, 2 to 3 times a day, 2 to 4 capsules each time.

Embodiment 3

[0090] Embodiment 3: tablet

[0091] Raw material formula: Yanhusuo 600g, Qingfengteng 600g, Pittosporum bark 400g, sliced ​​turmeric 400g

[0092] Preparation method: take Yanhusuo, Qingfengteng, Pittogonia bark, and turmeric slices, put them into 40% ethanol whose weight is 15 times the total weight of Corydalis chrysanthemum, Qingfengteng, Pittogonia bark, and sliced ​​turmeric, and reflux for extraction for 3 times. 3 hours each time, filter after each reflux, combine the filtrate and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.20 to 1.30, then add maltose, mix, dry, and pulverize, add carboxymethylcellulose sodium granules, and finally Magnesium stearate is added, granulated, blended, and tableted.

[0093] Functions and indications: heat-clearing and toxic substances removing, anti-inflammatory and analgesic. It is used to treat inflammation and pain caused by rheumatoid arthritis and rheumatic pain.

[0094] Dosage: Take...

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating rheumatoid arthritis and rheumatalgia and a preparation method and application of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation adopts bulk drugs, according to a ratio, 1-3 parts of rhizoma corydalis, 1-3 parts of caulis sinomenii, 1-3 parts of erythrina barks and 1-3 parts of wenyujin rhizoma concisum. The adopted preparation method is an alcohol extraction and percoaltion method. The traditional Chinese medicine preparation is used for clearing heat, resisting inflammation and easing pain, and has the efficacy of clearing heat and detoxifying the body, resisting inflammation and easing pain.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for treating rheumatic arthritis and rheumatic pain, a preparation method and application thereof. Background technique [0002] Rheumatoid arthritis is a common acute or chronic hoof tissue inflammation. The clinical manifestation is pain in the large joints of the whole body, with migratory characteristics. Patients are often accompanied by mild to moderate irregular fever. Invasion of knee joints, shoulder joints, elbow joints, ankle joints, wrist joints, etc., local red, swollen, hot, painful inflammation. In the acute stage, there are clinical manifestations of joint pain, and some patients have multiple joints involved at the same time, accompanied by nodules and erythema, and fever. The clinical manifestation of rheumatic pain is conscious joint pain, which is mostly migratory and intermittent, and is mostly induced b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P29/00A61P19/02
CPCA61K36/48A61K36/59A61K36/66A61K36/9066A61K2236/333A61K2236/39A61K2300/00
Inventor 刘涛朱红梅徐玉玲周蔚昕邓燕君陈桂华何秋蓉刘艺桦
Owner CHENGDU UNIV
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