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Feed formula for improving weaned piglet disease resistance and application

A technology for weaned piglets and disease resistance, which is applied in the fields of application, animal feed, animal feed, etc., can solve the problems of piglets’ innovation that needs to be improved, and achieve the effects of improving disease resistance, reducing content, and increasing the height of fluff

Inactive Publication Date: 2017-05-24
TIANJIN INST OF ANIMAL HUSBANDRY & VETERINARY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A review of recent literature shows that weaned piglet nutrition has always been a research hotspot and difficulty in the field of pig nutrition, and innovation in the field of piglet disease resistance needs to be improved

Method used

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  • Feed formula for improving weaned piglet disease resistance and application
  • Feed formula for improving weaned piglet disease resistance and application
  • Feed formula for improving weaned piglet disease resistance and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0109] Composition of compound feed ingredients for weaned piglets:

[0110] Including corn 61.59, soybean meal 20, whole milk powder 2.5, fish meal 6, wheat bran 2, glucose 3, acidulant 0.4, calcium hydrogen phosphate 0.7, stone powder 0.7, salt 0.3, L-lysine hydrochloride 0.4, DL-methionine 0.2, threonine 0.2, piglet premix 2, Clostridium butyricum 0.01 (the concentration in the diet is 1 × 10 5 CFU / g), Lactobacillus acidophilus 0.001 (the concentration in the diet is 1 × 10 4 CFU / g). The piglet premix mentioned therein means that each kilogram of premix contains: 14,600 mg iron, 630 mg copper, 410 mg manganese, 10,400 mg zinc, 15,000 μg iodine, 17,000 μg selenium, 227,600 IU VA, 22,800 IU VD 3 , 1,100 mg VE, 30 mg VK 3 , 700 mg VB 2 , 200 mg VB 6 , 1,340 mg pantothenic acid, 2,300 mg niacin, 8 mg biotin.

[0111] Preparation method: crush the two raw materials of corn and soybean meal, other raw materials do not need to be crushed, weigh them separately according to...

Embodiment 2

[0113] Composition of disease-resistant compound feed ingredients for weaned piglets:

[0114] Including corn 60, soybean meal 19.49, whole milk powder 4, fish meal 6, wheat bran 3.9, glucose 3, acidulant 0.3, calcium hydrogen phosphate 0.7, stone powder 0.6, salt 0.3, L-lysine hydrochloride 0.3, DL-methionine 0.2, threonine 0.2, piglet premix 1, Clostridium butyricum 0.001 (the concentration in the diet is 1×10 4 CFU / g), Lactobacillus acidophilus 0.01 (the concentration in the diet is 1×10 5 CFU / g).

[0115] The piglet premix mentioned therein means that each kilogram of premix contains: 14,600 mg iron, 630 mg copper, 410 mg manganese, 10,400 mg zinc, 15,000 μg iodine, 17,000 μg selenium, 227,600 IU VA, 22,800 IU VD 3 , 1,100 mgVE, 30 mg VK 3 , 700 mg VB 2 , 200 mg VB 6 , 1,340 mg pantothenic acid, 2,300 mg niacin, 8 mg biotin.

[0116] Preparation method: crush the two raw materials of corn and soybean meal, other raw materials do not need to be crushed, weigh them sep...

Embodiment 3

[0118] A disease-resistant compound feed for weaned piglets consists of the following raw materials in parts by weight:

[0119] Including corn 58, soybean meal 21, whole milk powder 3.08, fish meal 5, wheat bran 4, glucose 3, acidulant 0.4, calcium hydrogen phosphate 0.7, stone powder 0.7, salt 0.4, L-lysine hydrochloride 0.3, DL-methionine 0.2, threonine 0.2, piglet premix 3, Clostridium butyricum 0.01 (the concentration in the diet is 1×10 5 CFU / g), Lactobacillus acidophilus 0.01 (the concentration in the diet is 1×10 5 CFU / g).

[0120] Preparation method: crush the two raw materials of corn and soybean meal, other raw materials do not need to be crushed, weigh them separately according to the weight ratio, and mix them evenly in a small mixer.

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Abstract

The invention discloses a feed formula for improving weaned piglet disease resistance and application. The feed formula comprises the following raw materials: 58 to 63 parts of corn, 16 to 24 parts of bean pulp, 2 to 5 parts of whole milk powder, 4 to 9 parts of fish meal, 1 to 5 parts of wheat bran, 1 to 3 parts of glucose, 0.1 to 0.5 part of acidifying agent, 0.5 to 1.5 parts of calcium hydrophosphate, 0.5 to 1.1 parts of stone powder, 0.1 to 0.5 part of table salt, 0.3 to 0.7 part of L-lysine hydrochloride, 0.2 to 0.7 part of DL-methionine, 0.2 to 0.6 part of threonine, 1 to 4 parts of piglet premix, 0.001 to 0.01 part of clostridium butyricum additive and 0.001 to 0.01 part of lactobacillus acidophilus additive, wherein the weight part ratio of clostridium butyricum to lactobacillus acidophilus is 1 to 1, and the viable content of the two types of freeze-dried powder is 1*10<9>CFU / g (the concentration in a feed is 1*10<4> to 1*10<5> CFU / g). As proved by a result, the mRNA (messenger Ribonucleic Acid) level relative expressions of NLRP3, NLRP6 and NLRP12 in jejunum in an experimental group are improved remarkably; the villus heights of the middle segment of the jejunum and each intestinal segment of an ileum are increased remarkably, and the crypt depths of a duodenum, the middle segment of the jejunum and an ileum are decreased remarkably; the IL-1 beta content of serum is decreased, and the IL-10 content of the serum is increased. In the feed for weaned piglets, the clostridium butyricum additive and the lactobacillus acidophilus additive are added according to a proper proportion, so that the weaned piglet disease resistance can be improved remarkably.

Description

technical field [0001] The invention belongs to the research field of animal nutrition technology in animal husbandry, and relates to a feed formula using Clostridium butyricum and Lactobacillus acidophilus as feed additives, more specifically, a method for improving the expression of intestinal epithelial cytokines of weaned piglets, promoting intestinal Development of the mucosa of the tract and regulation of serum inflammatory factor levels. Background technique [0002] Ensuring the health of piglets and improving their disease resistance have been the hot and difficult points in the field of pig nutrition and feed research in recent years. The research on feed additives is developing in the direction of no residue, no drug resistance and no harm to human health and the environment. . Feed additives Clostridium butyricum and Lactobacillus acidophilus are widely used in animal production because of their unique pluripotency, probiotic effect and resistance to drug resist...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K10/18A23K50/30A23K50/60
CPCA23V2400/113
Inventor 乔家运李海花李玉鹏朱琪王文杰
Owner TIANJIN INST OF ANIMAL HUSBANDRY & VETERINARY
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