A traditional Chinese medicine composition for preventing or treating military stress disorder and its preparation method

A technology for stress disorder and composition, applied in the field of traditional Chinese medicine, can solve the problems of inability to be widely used in a large range, cure the symptoms but not the root cause, and have large toxic and side effects, and achieve the effects of adjusting the immune function of the body, enhancing the ability to resist diseases, and invigorating the spirit.

Active Publication Date: 2020-04-07
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This kind of psychiatric medicine treats the symptoms but not the root cause, and has large toxic and side effects. Therefore, it cannot be widely used as a good prescription for group prevention and treatment.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Embodiment 1, the preparation method of Chinese medicine composition of the present invention

[0045] Take Ganoderma lucidum 4kg, Ganoderma lucidum spores (broken wall) 3kg, Dendrobium 3kg, Ginseng 3kg, Astragalus 3kg, Ligustrum lucidum 2kg, Schisandra chinensis 2kg, light tempeh 2kg, tangerine peel 2kg, (total amount 24kg); Separately slice or crush into coarse powder, operate according to the following process:

[0046] 1) The supercritical fluid extraction process of Ganoderma lucidum spore essential oil: Get 3kg of Ganoderma lucidum spore powder (broken wall), and use supercritical CO 2 Extraction, the extraction process conditions are: extraction pressure 25Mpa, extraction temperature 60°C, extraction time 3h, collect the obtained Ganoderma lucidum spore essential oil extract for future use (essential oil A) to obtain 0.53kg of yellow-brown Ganoderma lucidum spore essential oil, calculate and record the oil yield of 17.75%, Ganoderma lucidum spore dregs are to be...

Embodiment 2

[0052] Embodiment 2, the preparation method two of Chinese medicine composition of the present invention comprise the following steps:

[0053] Take Ganoderma lucidum 2kg, Ganoderma lucidum spores (broken wall) 4kg, Dendrobium 4kg, Ginseng 2kg, Astragalus 4kg, Ligustrum lucidum 2kg, Schisandra 1.5kg, light tempeh 2.5kg, tangerine peel 2.5kg, (total 24.5kg); except Ganoderma lucidum spores , all kinds of medicinal materials are sliced ​​or broken into coarse powder respectively, and the operation is carried out according to the following process:

[0054] 1) The supercritical fluid extraction process of Ganoderma lucidum spore essential oil: Get 4kg of Ganoderma lucidum spore powder (broken wall), and use supercritical CO 2 Extraction, the extraction process conditions are: extraction pressure 35Mpa, extraction temperature 50°C, extraction time 2h, collect the obtained Ganoderma lucidum spore essential oil extract for future use (essential oil A), obtain light yellow brown Gano...

Embodiment 3

[0060] Embodiment 3. Preparation of soft capsules of traditional Chinese medicine composition for preventing and treating stress disorder.

[0061] Put 0.2kg each of the essential oil parts A and B of the Chinese medicine composition in a suitable container and keep warm at 50°C;

[0062] Mix 0.1kg of fine powders C and D, E0.2kg and F0.1kg of the effective part of the traditional Chinese medicine composition into the heat-retained essential oil part, add 0.1-0.3kg of tea oil with medicinal specifications, adjust the volume and viscosity of the contents, Grind with a colloid mill for many times, mix well, pass through a 120-mesh sieve, repeat the operation twice if necessary, homogenize the contents into a suspension, and prepare 1,000 soft capsules, each containing 1.0g-1.2g of contents , placed, granulated, washed, dried, packaged, inspected, and qualified finished products are obtained.

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PUM

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicinal composition for preventing or treating military stress disorders and a preparation method of the traditional Chinese medicinal composition. The traditional Chinese medicinal composition is prepared from lucid ganoderma, lucid ganoderma spore, herba dendrobii, radix ginseng, radix astragali, glossy privet fruits, fructus schisandrae, fermented soybean and dried tangerine or orange peel at a certain ratio. The traditional Chinese medicinal composition has the efficacies of benefiting qi for promoting production of fluid, tonifying the kidney and the spleen, tranquilizing the mind by nourishing the heart, relieving the exterior syndromes and restlessness, dispersing stagnated liver qi to relieve depression, nourishing Yin and suppressing Yang, and improving the body immunity. The pharmacological test proves that the traditional Chinese medicinal composition can obviously improve the behavior abnormality and immunologic function biochemical index change of stress disorder model rats, and has the efficacy of treating both manifestation and root cause of diseases. The clinical verification result shows that the traditional Chinese medicinal composition has the effective prevention and treatment effects for the stress disorders caused by various stimulating factors, and can obviously improve the symptoms including dysphoria and aypnia, willies, melancholy, moodiness, headache and heavy feeling in the brain, loss of appetite, fatigue and indolence, immunity decline, and the like.

Description

Technical field: [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a formula of a traditional Chinese medicine composition that can be used to prevent and treat stress disorder caused by various stimuli, and an extraction, separation, enrichment and preparation method of effective components. Background technique: [0002] Stress disorder refers to a group of mental disorders mainly caused by abnormal psychological reactions caused by psychological and social (environmental) factors. Common stressors include the following: A. Serious life events, such as serious traffic accidents; sudden death of relatives; being attacked by gangsters; being raped or major property losses. B. Major natural disasters, such as floods, earthquakes and fires, threaten life safety. C. War scenes, such as hand-to-hand combat between opposing sides. Stress disorder refers to various psychophysiological reactions caused by people's inability to e...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61P39/00A61P37/04A61P25/20A61P1/14A61P25/22A61P25/24A23L33/105A23L31/00
CPCA23V2002/00A61K36/074A61K36/258A61K36/48A61K36/481A61K36/57A61K36/638A61K36/752A61K36/79A61K36/8984A61K2236/333A61K2236/37A61K2236/39A61K2300/00A23V2200/30A23V2200/31A23V2200/324A23V2250/21A23V2250/208
Inventor 陆峰亓云鹏宓鹤鸣
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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