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Geo-authentic crude drug quality identification method based on multiple-spectral fusion

A quality identification and authentic technology, applied in the field of authentic medicinal material quality identification based on multi-spectral fusion, can solve problems such as time-consuming and laborious, and achieve the effects of less sample consumption, rapid spectral signal acquisition, and easy portability.

Inactive Publication Date: 2017-04-19
王海燕 +4
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AI Technical Summary

Problems solved by technology

In recent years, the rapid development of instrumental analysis methods such as chromatographic fingerprinting has made some progress in authentic Chinese medicinal materials, but chromatography, such as high performance liquid chromatography, generally requires a relatively complicated sample pretreatment process. More time-consuming and laborious

Method used

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  • Geo-authentic crude drug quality identification method based on multiple-spectral fusion
  • Geo-authentic crude drug quality identification method based on multiple-spectral fusion
  • Geo-authentic crude drug quality identification method based on multiple-spectral fusion

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Experimental program
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Embodiment Construction

[0049] The technical solutions of the present invention will be described in detail below in conjunction with the accompanying drawings.

[0050] In this example, Astragalus membranaceus, a representative medicinal material, is used as an authentic medicinal material for illustration.

[0051] Such as figure 1 As shown, a quality identification method of authentic medicinal materials based on multispectral fusion, the steps are as follows:

[0052]Step 1: Select astragalus produced in Gansu, Inner Mongolia, Shanxi, and Sichuan as samples, and pre-treat the samples:

[0053] Use a pulverizer to process (25000r / min, 3-10min) astragalus samples to obtain powder samples Take 3g of powder samples, place them in 30mL ethanol solution, mix well, stir at 100°C, and then react for 1h under reflux of condensed water, when The reaction system was naturally cooled to room temperature, and the filtrate was collected by filtration as the solution to be tested.

[0054] Step 2: Collect th...

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Abstract

The invention discloses a geo-authentic crude drug quality identification method based on multiple-spectral fusion. According to the geo-authentic crude drug quality identification method based on multiple-spectral fusion, ionic migration spectrum, Raman spectrum, and ultraviolet spectrum of traditional Chinese medicinal materials from different producing areas are collected; pattern recognition algorithm, including wavelet denoising, spectrogram normalization, kernel principal component analysis, and sparse classification algorithm, is adopted for fusion discrimination analysis of obtained multiple-spectral information. The geo-authentic crude drug quality identification method is capable of realizing rapid, accurate, and intelligent identification of traditional Chinese medicinal materials from different producing areas, increasing utilization rate of spectral information effectively, and increasing identification rate of geo-authentic crude drugs.

Description

technical field [0001] The invention belongs to the technical field of medicinal material identification, and in particular relates to an authentic medicinal material quality identification method based on multispectral fusion. Background technique [0002] Chinese medicinal materials are an important basis for the clinical efficacy of traditional Chinese medicine compounds, and Chinese medicinal materials from different origins are affected by various factors such as geographical location, climatic conditions, soil quality, temperature, humidity, etc., and then show different pharmacological effects and clinical efficacy. Taking Astragalus as an example, Astragalus is the dried root of the leguminous plant Astragalus mongolica or Astragalus membranaceus. It is a traditional Chinese medicinal material in my country. , mainly produced in Gansu, Inner Mongolia, Shanxi and many other provinces in China. However, in terms of clinical practice, the difference in the growth envir...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/65G01N21/33
CPCG01N21/33G01N21/65
Inventor 王海燕张正勇王祥胜刘军宋超
Owner 王海燕
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