Perilla leaf extract and application of perilla leaf extract composition to preparation of drugs or foods used for reducing blood uric acid

Abstract

The invention relates to a traditional herbal medicine-perilla leaf and a novel application of a traditional Chinese medicine composition of the perilla leaf. Through a mechanism of inhibiting xanthine oxidase activity and a mechanism of promoting uric acid to be discharged from urine, the concentration of uric acid in the blood of a body is reduced and the purposes of reducing uric acid and treating gout are achieved, so that perilla leaf extract and a traditional Chinese medicine composition of the perilla leaf extract can be applied to the preparation of drugs or foods used for preventing and treating the disease such as hyperuricemia, gout or the like. The perilla leaf extract and other traditional herbal medicines in the composition can be subjected to heating extraction by using water or hydrous ethanol as a solvent, the extraction is performed for 1-3 times, medicine residues are removed, the solvent is removed by reduced pressure concentration, powder is obtained through spray drying or freeze drying, and auxiliary materials are added to prepare a traditional Chinese medicine preparation or a food, particularly, a dosage form such as capsules, tablets, oral solutions, solid beverages or the like.

Description

technical field [0001] This patent relates to a perilla leaf extract and its composition for reducing uric acid in the blood, especially for the prevention or treatment of clinical hyperuricemia or hyperuricemia population. Background technique [0002] Perilla (scientific name: Perilla frutescens), ancient name Eren, also known as Su, Baisu, Guiren ("Er Ya"), Erzi, Chisu, Red Su, Fragrant Su, Black Su, White Perilla, Green Su , wild sage, suma, sage, Tang basil, wrinkled leaf sage, chicken sage, stinky stinky stalk, big basil, false basil, water cohosh, wild huoma, deaf ear hemp, zizhu, Xing Pasha karma ( Tibetan), etc., is the only species under the genus Perilla in Lamiaceae, an annual herb. Perilla leaf is also called Su Ye. It has the functions of relieving exterior cold, promoting qi and harmonizing stomach. It is mainly used for cold, cough, fullness of chest and abdomen, nausea and vomiting. Therapeutic effect, has expelling cold and relieving exterior syndrome, cl...

AI Technical Summary

Problems solved by technology

[0010] Although a variety of drugs for the treatment of hyperuricemia have been developed clinically, these drugs have relatively large side effects, and their clinical application is limited; new therapeutic drugs found from natural plants or Chinese medicinal materials have good development prospects. Invented in China Patent CN104162063 reports a traditional Chinese medicine compound preparation for the treatment of hyperuricemia and its preparation method, using natural Chinese medicine Gentiana as the main raw material; Chinese patent CN103372159A reports a coix seed extract with uric acid-lowering effect and its preparation method, etc.

At present, there is no report in the literature at home and abroad that perilla extract has the activity of lowering blood uric acid and its traditional Chinese medicine preparation containing perilla, coix seed, kudzu root, pagoda seed and corn silk has the use of reducing blood uric acid and treating gout

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