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Traditional Chinese medicine composition for treating and improving lower limb phlebothrombosis ad preparation method thereof

A technology of venous thrombosis and composition, which is applied in the field of traditional Chinese medicine composition for treating and improving lower extremity venous thrombosis and its preparation, can solve problems such as easy sequelae, difficulties for patients, and slow recovery, and achieve no toxic side effects and adverse reactions, Suitable for popularization and application, safe and reliable curative effect

Inactive Publication Date: 2017-02-22
BEIHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The current method of treating lower extremity venous thrombosis mainly adopts surgical treatment, but the recovery is relatively slow, the cost is high, and it is easy to leave sequelae
Although there are many kinds of drugs for treating lower extremity venous thrombosis, the effect is not very obvious, the treatment cycle is long, and the fees are high, which brings many difficulties and pains to patients and families.

Method used

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  • Traditional Chinese medicine composition for treating and improving lower limb phlebothrombosis ad preparation method thereof

Examples

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Effect test

Embodiment 1

[0050] In the embodiment of the present invention, a traditional Chinese medicine composition for treating and improving venous thrombosis of lower extremities is composed of the following components in terms of parts by mass: 1.2 parts of Cypripedium variegata, 45.0 parts of zinnia, 18.0 parts of red and green grass, Tahuang 4.8 parts, sugar mustard 3.0 parts.

[0051] The preparation method of the Chinese medicine composition for treating and improving lower extremity venous thrombosis, the specific steps are:

[0052] (1) After crushing Cypripedium variegata and passing through a 40-mesh sieve, add hot water at a temperature of 68°C that is 4 times the mass of Cypripedium variegata for hot leaching for 1.5 hours to obtain an extract of Cypripedium variegata and dipper Slag 1, high-speed centrifugation of the extract of Cypripedium variegata, the centrifugation speed is 5200r / min, and the centrifugation time is 20min, after centrifugation, the extract of Cypedium varibetum a...

Embodiment 2

[0058] In the embodiment of the present invention, a traditional Chinese medicine composition for treating and improving venous thrombosis of lower extremities is composed of the following components in terms of parts by mass: 1.6 parts of Cypripedium variegata, 38.0 parts of zinnia, 22.0 parts of red and green grass, Tahuang 3.5 parts, sugar mustard 4.2 parts.

[0059] The preparation method of the traditional Chinese medicine composition for treating and improving lower extremity venous thrombosis is the same as that of Example 1.

Embodiment 3

[0061] In the embodiment of the present invention, a traditional Chinese medicine composition for treating and improving venous thrombosis of lower extremities is composed of the following components in terms of parts by mass: 1.3 parts of Cypripedium variegata, 43.0 parts of zinnia, 18.0 parts of red and green grass, Tahuang 4.5 parts, sugar mustard 3.5 parts.

[0062] The preparation method of the traditional Chinese medicine composition for treating and improving lower extremity venous thrombosis is the same as that of Example 1.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating and improving lower limb phlebothrombosis ad a preparation method thereof; the traditional Chinese medicine composition is prepared from, by weight, 1.2-1.6 parts of herb of Cypripedium guttatum, 38.0-45.0 parts of herb of Zinnia elegans, 18.0-22.0 parts of herb of Alternanthera versicolor, 3.5-4.8 parts of rhizome of Rheum nobile, and 3.0-4.2 parts of Semen Erysimi Diffusi; herb of Cypripedium guttatum is thermally extracted and centrifuged to obtain liquid extract, filter residue is extracted via supercritical carbon dioxide to obtain extract, the liquid extract and the extract are combined and concentrated into thick paste; herb of Zinnia elegans and herb of Alternanthera versicolor are subjected to double ethanol heating reflux extraction, and extracts are combined and concentrated and dried into dry paste; rhizome of Rheum nobile is subjected to ethanol high-temperature stirring extraction, and extract is centrifuged to obtain liquid extract; Semen Erysimi Diffusi is subjected to triple ultrasonic extraction to obtain liquid extract; the extracts above are mixed to obtain granules. The traditional Chinese medicine composition is effective in dispersing stasis and dredging channels, and removing dampness and clearing heat, has total effective efficiency in clinical treatment of lower limb phlebothrombosis being 100%, and has cure rate of four treatment courses up to 100%.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating and improving lower extremity venous thrombosis and a preparation method thereof. Background technique [0002] Venous thrombosis refers to a disease in which acute non-suppurative inflammation occurs in veins and secondary thrombosis occurs under the conditions of sluggish venous blood flow, blood hypercoagulability, and vascular intima injury. The vast majority of venous thrombosis occurs in the deep veins of the pelvis and lower extremities. It is more common in postpartum, fracture and trauma, and postoperative patients. If limb pain, swelling, and palpable cords along the veins appear, the possibility of this disease should be considered. Ultrasound Doppler, radionuclide venography can help diagnosis. Thrombosis is easy to fall off in the early stage, which can cause large pulmonary infarction an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/16A61P9/14A61P7/02
CPCA61K36/898A61K9/1605A61K36/185A61K36/28A61K36/31A61K36/708A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 杨云龙王薇程静
Owner BEIHUA UNIV
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