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Glycosylated hemoglobin/blood sugar integrated detection bigeminy strip and preparation method thereof

A technology for glycosylated hemoglobin and blood sugar, applied in measuring devices, biological testing, material inspection products, etc., can solve the problems of not reflecting the state of blood sugar control, insufficient, etc., and achieve the effect of rapid report results, reasonable cost and convenient operation

Inactive Publication Date: 2017-01-25
GETEIN BIOTECH
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Problems solved by technology

[0006] 5. At present, we can use the blood glucose meter to achieve the purpose of rapid blood glucose detection. This detection method is basically consistent with the blood glucose value measured by venous blood drawing, but it is far from enough to evaluate whether the blood glucose control is up to standard, because rapid blood glucose detection is only It can reflect the blood sugar content at that time point, but cannot reflect the long-term control status of blood sugar

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  • Glycosylated hemoglobin/blood sugar integrated detection bigeminy strip and preparation method thereof

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Embodiment Construction

[0020] 1. The diffusion membrane 1 is simultaneously covered on the blood filtration membrane 2 of the blood glucose detection reagent strip and the sample pad of the glycation detection reagent strip 8;

[0021] 2. The blood glucose reaction film 4 contains a diluent and a reaction reagent, wherein the diluent includes a buffer, a surfactant, a stabilizer, an adhesive, a coenzyme factor, and a preservative; the reaction reagent includes glucose oxidase, peroxidase , 4-aminoantipyrine and N-ethyl-N(2-hydroxy-3-propanesulfo)-3,5-dimethylaniline. Using the Trinder reaction reagent as an indicator probe, when the analyte generates hydrogen peroxide (H2O2) through enzyme action, peroxidase can catalyze 4-aminoantipyrine (4-AAP) and H2O2 to produce colored quinone chemicals and water;

[0022] 3. The dry immunofluorescent reagent strip 8 for detecting glycosylated hemoglobin is respectively provided with a detection line for albumin and a first quality control line, and the detect...

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Abstract

The invention relates to a glycosylated hemoglobin / blood sugar integrated detection bigeminy strip. The glycosylated hemoglobin / blood sugar integrated detection bigeminy strip comprises a sample area and a reaction area, and is characterized in that two indices share the single sample area; the reaction area comprises two different detection windows; the two indices, namely glycosylated hemoglobin and blood sugar, can be detected simultaneously; the sample area where the blood sugar is detected by a dry chemical method is located in the same position as the reaction area; the reaction area where the glycosylated hemoglobin is detected by a dry immunofluorescence technique is 0.5 cm away from the sample area. The different reaction areas contain different reagent pads to independently react with corresponding ingredients in blood respectively. The synchronous detection can be achieved only by quantitatively dropping a blood sample (whole blood) of a detected person into the sample area, and the strip is very applicable to medical institutions or individuals. The strip can simultaneously detect the two very important blood sugar monitoring indices, help a patient to find a problem at any moment and reflect the blood sugar control level of the patient within a time period, and is very important for preventing, treating and controlling complications of diabetes mellitus.

Description

technical field [0001] The invention relates to an integrated detection double strip of glycosylated hemoglobin / glucose, which is used for clinical in vitro quantitative detection of the content of glycosylated hemoglobin (HbA1c) in human whole blood and the content of glucose (Glu) in whole blood, and belongs to the technical field of clinical in vitro diagnosis . Background technique [0002] 1. Long-term abnormal blood sugar will lead to abnormal function of cardiovascular and cerebrovascular and microvascular, complications and increased mortality. Self-monitoring of blood sugar is an effective way for diabetics to keep abreast of their own conditions and conditions. It is very important for controlling diabetes, preventing complications, and improving the quality of life of diabetics. The latest research shows that the incidence rate of type II diabetes in my country has reached 11.6%, ranking first in the world, that is to say, at least one person in every ten people ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/72G01N33/66G01N33/533
CPCG01N33/723G01N33/533G01N2800/042
Inventor 童鎏黄力刘佳吴礼新苏恩本
Owner GETEIN BIOTECH
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